Nateglinide

Description

Nateglinide is a medicine used to control high blood sugar levels in adults with Type II Diabetes. In type 2 diabetes, the body either does not produce enough insulin or resists insulin. This medicine works by increasing the production of insulin in your body. Nateglinide has some side effects like headache, runny nose, dizziness, thirst, increased urination, constipation, diarrhoea, joint pain, and back pain. These symptoms may subside by themselves. Consult your doctor if they bother you. This medicine may cause hypoglycemia (low blood sugar levels), therefore always carry a sugar candy to balance the sugar levels while on treatment with this medicine. Avoid driving vehicles and operating machines after taking this medicine as it may affect your concentration. Nateglinide should be taken 30 minutes before a meal or as prescribed by your doctor. The dose and duration of the treatment depend on the severity of your condition. Take this medicine every day at the same time for the ease of remembering and for better results. Do not take more than the prescribed dose. Nateglinide is not recommended for use in children below 18 years of age. Inform your doctor if you have Type 1 diabetes (a condition in which your immune system destroys insulin-making cells in your pancreas), liver, and kidney problems before starting the treatment with this medicine. Consult your doctor if you are pregnant or breastfeeding before taking this medicine.

Side effects

Major & minor side effects for Nateglinide

  • Convulsions (seizures)
  • Unconsciousness
  • Confusion
  • Blurred vision
  • Excessive hunger
  • Difficulty in thinking
  • Nausea
  • Nervousness
  • Slurred speech
  • Headache
  • Runny nose
  • Joint pain
  • Back pain
  • Diarrhoea
  • Constipation

Uses of Nateglinide

What is it prescribed for?

  • Type II Diabetes Mellitus
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Concerns

Commonly asked questions

  • Onset of action
    Nateglinide starts showing its effect within 20 minutes after intake.
  • Duration of effect
    The effect of Nateglinide lasts for an average duration of 4 hours.
  • Safe with alcohol?
    Avoid consumption of alcohol during the treatment with Nateglinide as it can cause very low blood sugar levels and increase the risk of severe side effects.
  • Is it habit forming?
    No habit-forming tendencies were reported for Nateglinide.
  • Usage in pregnancy?
    Nateglinide is not recommended for use in pregnancy. If you are pregnant, consult your doctor before using this medicine.
  • Usage while breast-feeding?
    Nateglinide is not recommended for use during breastfeeding. If you are breastfeeding, consult your doctor before using this medicine.

Allergy

Avoid taking Nateglinide if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Diabetic ketoacidosis

Diabetic ketoacidosis is a serious complication of diabetes that occurs when your body produces high levels of blood acids called ketones. Nateglinide is not recommended for use if you have this condition as it may cause serious side effects.

Type I Diabetes mellitus

Type 1 diabetes is a condition in which your immune system destroys insulin-making cells in your pancreas. Nateglinide is not effective to treat this condition and it may worsen your condition.
Warnings for special population

Pregnancy

Nateglinide is not recommended for use in pregnancy. If you are pregnant, consult your doctor before using this medicine.

Breast-feeding

Nateglinide is not recommended for use during breastfeeding. If you are breastfeeding, consult your doctor before using this medicine.
General warnings

Use in children

Nateglinide is not recommended for use in your children under 18 years of age as the safety and efficacy data are not available.

Hypoglycemia

Hypoglycemia is low blood sugar levels. Use Nateglinide with extreme caution due to the increased risk of sudden hypoglycemia. Report any symptoms such as drowsiness, weakness, dizziness, lightheadedness, etc., to your doctor immediately. Always carry a sugar candy to overcome these symptoms while you are on treatment with this medicine.

Driving or operating machines

Avoid performing activities such as driving vehicles or operating machines after taking Nateglinide as it may affect your concentration and make you feel drowsy.

Missed Dose

Take the missed dose of Nateglinide as soon as you remember. However, if you have finished your meal, skip the missed dose and continue with the next scheduled dose. Do not take two doses at a time to make up for the missed dose.

Overdose

Never take more than the prescribed dose. Seek emergency medical treatment in case of an overdose with Nateglinide.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consumption of alcohol during the treatment with Nateglinide as it can cause very low blood sugar levels and increase the risk of severe side effects.
Interaction with Medicine

Aspirin

Gemfibrozil

Diclofenac

Furosemide

Gatifloxacin

Benazepril

Bisoprolol

Disease interactions

Heart diseases

Nateglinide is not recommended for use if you have heart problems as it may cause serious side effects and worsen your condition.

Liver disease

Use Nateglinide with extreme caution if you have liver problems due to the increased risk of worsening your health condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Nateglinide 30 minutes before meals or as prescribed by your doctor. Do not take more or fewer doses than prescribed. Consult your doctor if you experience any undesirable effects. Do not stop the use of this medicine without consulting your doctor. It may cause hypoglycemia (lower blood sugar levels). Hence, carry sugar candy to overcome the symptoms of hypoglycemia like weakness and thirst. Keep the medicine away from the reach of children and pets. Ensure that the unused medicine is disposed of properly.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

Causes sleepiness

How it works
Nateglinide works by acting on the pancreas to release insulin in your body, which prevents the rise in blood sugar levels after a meal.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Meglitinides, Antidiabetic agents

Schedule

Schedule H

Medicines.org.uk. 2021. Starlix 60mg film coated tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 14 September 2021].

https://www.medicines.org.uk/emc/product/1320/smpc#CLINICAL_PRECAUTIONS>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 14 September 2021].

https://www.medicines.org.uk/emc/files/pil.1320.pdf>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 14 September 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021204s011lbl.pdf>

Dailymed.nlm.nih.gov. 2021. DailyMed - NATEGLINIDE tablet, coated. [online] Available at: < [Accessed 14 September 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c678b772-acba-4b59-a0b2-d70d84283425>

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Information on this page was last updated on 10 Nov 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.