Narcotan 400 mcg Injection

Manufactured byTroikaa Pharmaceuticals Ltd.
ContainsNaloxone
Description

Narcotan 400 mcg Injection is an antidote used in the treatment of narcotic overdose during critical and emergency situations. This medicine should only be taken under the supervision of a trained healthcare professional.

Substitutes

List of substitutes for Narcotan 400 mcg Injection

Side effects

Major & minor side effects for Narcotan 400 mcg Injection

  • Abdominal and stomach cramps
  • Sweating
  • Loss of consciousness
  • Seizures
  • Increased blood pressure
  • Increased heartbeat
  • Nausea and Vomiting

Uses of Narcotan 400 mcg Injection

What is it prescribed for?

  • Opioid overdose
  • Postoperative Opioid Depression
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its effect is approximately 2 minutes for an intravenous dose and 2-5 minutes for an intramuscular and a subcutaneous dose.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is about 1-2 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless potential benefits outweigh the potential risks.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless potential benefits outweigh the potential risks.

Allergy

This medicine is not recommended for use in patients with a known allergy to naloxone.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless potential benefits outweigh the potential risks.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless potential benefits outweigh the potential risks.
General warnings

Liver Disease

This medicine should be used with caution in patients with a history of liver disease or active liver disease. Close monitoring of liver functions is advised during treatment with this medicine.

Septic Shock

Narcotan 400 mcg Injection should be used with caution during conditions like septic shock due to the increased risk of side effects such as nausea and vomiting, pulmonary edema, hypotension, cardiac arrhythmias, and seizures. Appropriate dose adjustments or replacement with a suitable alternative should be done based on the clinical condition of the patient.

Missed Dose

Since this medicine is given by a qualified healthcare professional either in emergency situations or postoperatively, the likelihood of missing a dose is very less.

Overdose

Since this medicine is administered either in emergency situations or postoperatively by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Droperidol

Naloxegol

Disease interactions

Cardiovascular disorders

This medicine is not recommended for use in patients with a known history of cardiovascular diseases. Close monitoring of heart and lung function is recommended during treatment with this medicine.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine should be administered by a qualified healthcare professional. All the vital functions of the patient should be monitored closely during treatment with this medicine. The patient should be monitored closely for any undesired side effects.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
Narcotan 400 mcg Injection works by blocking or reversing the effects of opioids including respiratory depression, sedation, and hypotension.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Antidotes

Schedule

Schedule X

[Internet]. 2017 [cited 27 July 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/23885

DailyMed - NALOXONE HYDROCHLORIDE- naloxone hydrochloride injection [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 27 July 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=236349ef-2cb5-47ca-a3a5-99534c3a4996

Naloxone - DrugBank [Internet]. Drugbank.ca. 2017 [cited 27 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB01183

Naloxone Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 27 July 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a612022.html

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 27 July 2017]. Available from:

http://www.tga.gov.au/prescribing-medicines-pregnancy-database
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