Nabumetone
Description
Nabumetone is used to relieve pain and inflammation in conditions such as Osteoarthritis and Rheumatoid Arthritis.
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Side effects
Major & minor side effects for Nabumetone
- Hypersensitivity
- Headache
- Allergic skin reaction
- Swelling or inflammation of mouth
- Vomiting
- Bleeding gums
- Blood in urine and stools
- Blurred vision
- Sleepiness
- Yellowing of skin and eyes
- Swelling
- Tinnitus
Uses of Nabumetone
What is it prescribed for?
- Osteoarthritis
- Rheumatoid Arthritis
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Concerns
Commonly asked questions
- Onset of actionThe amount of time required for this medicine to show its action is not clinically established.
- Duration of effectThe amount of time for which this medicine remains active in the body is not clinically established.
- Safe with alcohol?Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc.
- Is it habit forming?No habit-forming tendencies were reported.
- Usage in pregnancy?This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
- Usage while breast-feeding?This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
Allergy
This medicine is not recommended for use in patients with a known allergy to nabumetone or any other components present along with it.
Coronary Artery Bypass Surgery (CABG)
Nabumetone is not recommended for use in the setting of Coronary artery bypass graft surgery (CABG) due to the increased risk of severe adverse effects.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings
Use in last trimester of pregnancy
This medicine is not recommended for use in women in the last trimester of pregnancy.
Hypertension
Nabumetone may cause new-onset hypertension or may worsen the pre-existing hypertensive condition. Close monitoring of blood pressure is recommended throughout the course of therapy. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Effect on female fertility
Nabumetone may cause an impairment of female fertility in some cases. Hence, it is not recommended for use in women of childbearing potential who want to conceive.
Geriatric use
Caution is advised while using this medicine in the elderly patients due to an increased risk of excessive bleeding. Appropriate dose adjustments may be required based on the clinical condition. Report any symptoms such as unusual bleeding or bruising, blood in vomit or stool, etc. to the doctor immediately.
Masking of infections
Nabumetone may mask the signs or symptoms of infections such as fever, pain, and swelling.
Missed Dose
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.
Overdose
Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
N/A
Instructions
Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc.
Interaction with Medicine
Prasugrel
Adefovir
Deferasirox
Sirolimus
Dalteparin
Disease interactions
Asthma
This medicine is not recommended for use in patients with a known history of NSAID-sensitive or aspirin-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.
Fluid retention and edema
This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases.
Skin rash
This medicine may cause fatal skin allergies without any warnings in some patients. Signs and symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
Renal Dysfunction
This medicine should be used with caution in patients with a history of kidney diseases or active kidney diseases due to the increased risk of severe adverse effects. Close monitoring of the renal function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Thrombosis
Nabumetone may worsen the risk of heart attack and stroke when used for a prolonged period of time. Hence, the lowest effective dose of this medicine should be used for the shortest possible duration in patients at a risk of thrombotic events. Addition of antiplatelet medicines may be required to reduce the risk of thrombotic events. Patients are advised to seek emergency medical attention in case of any unusual weakness, shortness of breath, or chest pain. Replacement with a suitable alternative may be necessary based on the clinical condition.
Anemia
Nabumetone should be used with caution in patients with a history of anemia or patients predisposed to anemia since it may cause a decrease in the hemoglobin and hematocrit levels. Close monitoring of hemoglobin and hematocrit levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Hyperkalemia
This medicine should be used with caution due to an increase in the risk of hyperkalemia (increased potassium levels). This risk is especially higher in patients with a history of kidney diseases. Close monitoring of potassium levels, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.
Gastro-Intestinal toxicity
This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Nabumetone exactly as instructed by the doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous
How it works
Nabumetone works by blocking the formation of chemical substances which cause pain and swelling.
Legal Status
Classification
Category
Antirheumatics, Nonsteroidal anti-inflammatory agents
Schedule
N/A
DailyMed - Nabumetone tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 11 September 2017]. Available from:
[Internet]. 2017 [cited 11 September 2017]. Available from:
Toxnet [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 11 September 2017]. Available from:
Nabumetone: DrugBank [Internet]. Drugbank.ca. 2017 [cited 11 September 2017]. Available from:
Nabumetone: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 11 September 2017]. Available from:
[Internet]. 2017 [cited 11 September 2017]. Available from:
Information on this page was last updated on 3 Oct 2017
Disclaimer
We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.