Myticef 250 mg Injection

Manufactured byPanacea Biotec Ltd.
ContainsCefoperazone
Description

Myticef 250 mg Injection is a third-generation cephalosporin antibiotic used in the treatment of infections of skin and skin structures, respiratory tract, urinary tract, gynecological infections including gonorrhea, intraabdominal infections, and septicemia caused by susceptible microorganisms. It is not recommended for use in patients who are allergic to cephalosporins or penicillins.

Substitutes

List of substitutes for Myticef 250 mg Injection

Magnamycin 250 mg Injection
Pfizer Ltd.

Side effects

Major & minor side effects for Myticef 250 mg Injection

  • Hypersensitivity
  • Seizures
  • Pseudomembranous colitis
  • Diarrhea
  • Nausea and vomiting
  • Itching or rash
  • Unusual bleeding
  • Neutropenia
  • Pain at the injection site
  • Injection site Thrombophlebitis
  • Superinfection

Uses of Myticef 250 mg Injection

What is it prescribed for?

  • Respiratory Tract Infection
  • Urinary Tract Infection
  • Bacterial Septicemia
  • Skin and Skin Structure Infection
  • Gynecological infections
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed rapidly after administration of the dose through the intramuscular (IM) or the intravenous (IV) route.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 12 hours after IM or IV administration.
  • Safe with alcohol?
    Use of Myticef 250 mg Injection within 48-72 hours of alcohol ingestion may cause a disulfiram like-reaction. This reaction is characterized by severe vomiting, abdominal pain, headache, palpitations, difficulty in breathing, sweating, and an increased heart rate. Consumption of alcohol is not recommended during treatment with this medicine and for several days after the therapy has been stopped. Any unusual symptoms should be reported to the doctor on priority.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    Use of this medicine in pregnant women is not recommended unless absolutely necessary. Discuss with the doctor all the potential benefits and risks before receiving this medicine.
  • Usage while breast-feeding?
    This medicine may be used in breastfeeding women if necessary. Discuss all the risks and benefits with your doctor before receiving this medicine. If the medicine is used, the breastfed infant should be monitored closely for any adverse effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to cefoperazone or any other medicines of the cephalosporin or beta-lactam class of antibiotics.
Warnings for special population

Pregnancy

Use of this medicine in pregnant women is not recommended unless absolutely necessary. Discuss with the doctor all the potential benefits and risks before receiving this medicine.

Breast-feeding

This medicine may be used in breastfeeding women if necessary. Discuss all the risks and benefits with your doctor before receiving this medicine. If the medicine is used, the breastfed infant should be monitored closely for any adverse effects.
General warnings

Allergy

This medicine is not recommended for use in patients with a known allergy to cefoperazone or any other medicines of the cephalosporin and beta-lactam class of antibiotics. Seek immediate medical attention if you experience any allergic symptoms such as a rash; itching; nausea or vomiting; or swelling of the lips, hands, and feet.

Drug resistance

Usage of Myticef 250 mg Injection without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and may even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Clostridium difficile-associated Diarrhea

Do not use if you experience severe diarrhea after receiving Myticef 250 mg Injection. Antibiotic therapy will cause an imbalance in the normal microbial flora in the large intestine. This may decrease the gut friendly bacteria and may promote the growth of a bacteria called Clostridium difficile, resulting in diarrhea.

Impaired kidney function

This medicine should be used with caution in patients suffering from any kidney disease. Appropriate dose adjustments are to be made based on CrCl.

Hepatic/biliary obstruction

This medicine should be used with extreme caution in patients with a known history of liver diseases or active liver diseases. Since this medicine is excreted mainly through bile, a hepatic or biliary obstruction may increase the levels of Myticef 250 mg Injection by 2-4 folds. The daily dose should not exceed 4 g for such patients. If a dose of more than 4 g is required, close monitoring of serum concentrations of the medicine and liver function is advised.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already the time for your next scheduled dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact a doctor immediately in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Use of Myticef 250 mg Injection within 48-72 hours of alcohol ingestion may cause a disulfiram like-reaction. This reaction is characterized by severe vomiting, abdominal pain, headache, palpitations, difficulty in breathing, sweating, and an increased heart rate. Consumption of alcohol is not recommended during treatment with this medicine and for several days after the therapy has been stopped. Any unusual symptoms should be reported to the doctor on priority.
Interaction with Medicine

Aminoglycoside antibiotics

Loop diuretics

Anticoagulants

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions

Benedict's or Fehling's Test

Myticef 250 mg Injection may give a false positive result for glucose in the urine with Benedict's or Fehling's reagent. It is advised that you inform the doctor about all the medicines you are using before undergoing lab tests to avoid such results. Do not stop the use of any medicine without consulting with your doctor.

Coomb's test

Use of Myticef 250 mg Injection may give a false positive result for Coomb's test. This test is used to detect anemia caused by the excessive destruction of red blood cells. It is advised that you inform the doctor about all the medicines you are using before undergoing lab tests to avoid such results. Do not stop the use of any medicine without consulting with your doctor.
This medicine should be taken under the supervision of a qualified healthcare professional. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Consult the doctor if you experience any undesirable effects. Do not stop taking this medicine before the completion of the entire course.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Myticef 250 mg Injection works by interfering with the bacterial cell wall formation and thus stops the growth of bacteria.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Third generation cephalosporins

Schedule

Schedule H1

Cefoperazone - DrugBank [Internet]. Drugbank.ca. 2017 [cited 1 July 2017]. Available from:

https://www.drugbank.ca/drugs/DB01329

TOXNET [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 31 July 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~e2NoXe:4

[Internet]. 2017 [cited 31 July 2017]. Available from:

https://davisplus.fadavis.com/3976/meddeck/pdf/cefoperazone.pdf

[Internet]. 2017 [cited 31 July 2017]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/050551s043lbl.pdf

Cefoperazone (substance) [Internet]. Snomedbrowser.com. 2017 [cited 31 July 2017]. Available from:

http://www.snomedbrowser.com/Codes/Details/372743004
Loading related questions...

How will this medicine affect me?

Chat with verified doctors starting @ ₹99
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Something doesn’t feel right?
Report an error