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Myotop Dsr (100/450 mg) Tablet
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Myotop Dsr (100/450 mg) Tablet

Manufactured byZuventus Healthcare Ltd.
ContainsDiclofenac (100 mg) + Tolperisone (450 mg)
Description
Myotop Dsr (100/450 mg) Tablet is a combination medicine used for the treatment of acute muscle or musculoskeletal spasms in adults. It relieves symptoms such as muscle stiffness, joint pain, etc. associated with muscular contractions.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Myotop Dsr (100/450 mg) Tablet

  • Abdominal pain
  • Diarrhea
  • Nausea and Vomiting
  • Skin Rash
  • Dry mouth
  • Muscle weakness
  • Breathlessness
  • Low blood pressure
  • Swelling of eyes and lips
  • Abdominal discomfort
  • Dizziness
  • Fatigue
  • Redness of skin
  • Indigestion
  • Increased heartrate

Uses of Myotop Dsr (100/450 mg) Tablet

What is it prescribed for?

  • Muscle spasticity
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 10 minutes of administration of the dose.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to diclofenac, other NSAIDs, tolperisone, or any other inactive ingredient present along with them.

Myasthenia gravis

This medicine is not recommended for use in patients with a known history of myasthenia gravis due to the increased risk of worsening of the patient's condition.

Peptic Ulcer

This medicine is not recommended for use in patients with peptic ulcer disease due to the increased risk of worsening of the patient's condition.

Severe renal impairment

This medicine is not recommended for use in patients with severe renal impairment due to the increased risk of serious adverse effects.

Severe heart failure

This medicine is not recommended for use in patients with severe heart failure due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Heart disease

This medicine should be used with caution in patients with heart diseases due to the increased risk of adverse effects on the heart, especially after a prolonged use. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Coronary Artery Bypass Surgery

This medicine should not be taken to relieve muscle spasms before, during, or after a coronary artery bypass graft surgery due to the increased risk of severe adverse reactions.

Gastro-intestinal bleeding

This medicine may cause severe gastrointestinal bleeding and perforation after prolonged usage. These adverse events may occur with or without warning symptoms. This risk is especially higher in the elderly population and in patients with a history of gastrointestinal diseases. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Dizziness

This medicine may make you feel sleepy or dizzy. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating heavy machinery if you experience these symptoms during treatment with this medicine.

Liver impairment

This medicine should be used with caution in patients with liver impairment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Missed Dose

If a dose of this medicine is missed, take the dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc.
Interaction with Medicine

Allopurinol

Methotrexate

Ramipril

Aspirin

Adefovir

Apixaban

Ketorolac

Probenecid

Methocarbamol

Tetracyclines

Disease interactions

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Fluid Retention and edema

This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases.

Gastro-Intestinal toxicity

This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Skin Rash

This medicine may cause fatal skin allergies without any warnings in some patients. Signs and symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Heart attack and stroke

This medicine may cause a heart attack, stroke, or other associated symptoms after a prolonged use. This risk is especially higher in patients with a history of heart diseases. Close monitoring of heart function is recommended for such patients. Report any symptoms such as a chest pain, shallow breathing, speech slurring, weakness, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. This medicine should be taken with food. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Diclofenac works by reducing the formation of certain substances in the body that cause pain and swelling. Tolperisone relaxes the muscles and reduces the pain. The combination is thus effective in treating muscle contractions and rigidity.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Analgesics, Muscle relaxants

Schedule

Schedule H

[Internet]. Inceptapharma.com. 2017 [cited 14 September 2017]. Available from:

http://www.inceptapharma.com/view-product.php?pid=82
SI J. Design and Development of Tolperisone Hcl and Diclofenac Sodium Sustained Release Tablet. Journal of Drug Research and Development. 2016;1(2).

Diclofenac: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 14 September 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a689002.html

[Internet]. 2017 [cited 14 September 2017]. Available from:

http://www.stridesarco.com/pdf/Branded/india/orthopedic/myo_mr.pdf

Beximco [Internet]. 2017 [cited 14 September 2017]. Available from:

http://www.beximcopharma.com/images/stories/product-pdf/Tolmus.pdf

[Internet]. 2017 [cited 21 September 2017]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019201s039s040lbl.pdf
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Information on this page was last updated on 24 Sep 2017

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