Mozep 2 mg Tablet

Manufactured byIntas Pharmaceuticals Ltd.
ContainsPimozide
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Description

Mozep 2 mg Tablet is used to treat an uncontrollable need to repeat certain movements or sounds associated with Tourette's syndrome. It is only used when other medicines are not effective for treating this condition.

Substitutes

List of substitutes for Mozep 2 mg Tablet

Side effects

Major & minor side effects for Mozep 2 mg Tablet

  • Dizziness
  • Sedation
  • Visual disturbances
  • Dry mouth
  • Impotence
  • Convulsions
  • Irregular heartbeat
  • Increased thirst
  • Change in taste
  • Difficulty in swallowing
  • Swelling of face
  • Menstrual changes
  • Rash
  • Constipation
  • Sensitivity to light

Uses of Mozep 2 mg Tablet

What is it prescribed for?

  • Tourette's Syndrome
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to pimozide.

Congenital long QT syndrome

This medicine is not recommended for use in patients with a known history of congenital long QT syndrome due to the increased risk of worsening of the patient's condition.

Neutropenia

This medicine is not recommended for use in patients with severe neutropenia due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

CYP 2D6 inhibitors

This medicine is not recommended for use with other strong CYP 2D6 inhibitors due to the increased risk of severe side effects.

Acute alcohol intoxication

This medicine is not recommended for use in patients with acute alcohol intoxication due to the increased risk of respiratory depression or coma.

Tardive Dyskinesia

Prolonged use of this medicine may cause symptoms of tardive dyskinesia, a condition characterized by involuntary movements of tongue, lips, face, jaw, trunk, and/or the extremities. Therapy may need to be discontinued based on the clinical condition of the patient.

Tics

This medicine is not recommended for use in patients with simple tics or tics other than those associated with Tourette's syndrome.

Hyperprolactinemia

This medicine should be used with caution in patients with a history of hyperprolactinemia since this medicine may further elevate serum prolactin levels. Close monitoring of prolactin levels is recommended for such patients. The therapy may be discontinued based on the clinical condition of the patient.

Parkinsonism

This medicine should be used with extreme caution in patients with a history of parkinsonism due to the increased risk of worsening of the patient's condition.

Renal diseases

This medicine should be used with caution in patients with severe renal diseases due to the increased risk of serious side effects.

Liver diseases

This medicine should be used with caution in patients with severe liver diseases due to the increased risk of serious side effects.

Missed Dose

If a dose of Mozep 2 mg Tablet is missed, take the dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Nefazodone

Protease inhibiors

CYP450 2D6 inhibitors

Zileuton

Disease interactions

Dementia

This medicine is not recommended for use in elderly patients with dementia due to the increased risk of death. An alternative treatment option should be considered based on the clinical condition.

Central Nervous System Depression

This medicine is not recommended for use in patients with central nervous system depression or comatose state due to the increased risk of worsening of the patient's condition. An alternative treatment option should be considered based on the clinical condition.

Neuroleptic Malignant Syndrome (NMS)

This medicine should be used with extreme caution in patients with a history of Neuroleptic Malignant Syndrome (NMS) due to the increased risk of recurrence of NMS. An alternative treatment option should be considered based on the clinical condition.

Seizure disorders

This medicine should be used with extreme caution in patients with seizure disorders due to the increased risk of worsening of the patient's condition. An alternative treatment option should be considered based on the clinical condition.

Pituitary tumors

This medicine should be used with caution in patients with a history of pituitary tumors due to the increased risk of worsening of the patient's condition. An alternative treatment option should be considered based on the clinical condition.
Food interactions
Consumption of caffeine is not recommended during treatment with this medicine. Combined use may increase the levels of Mozep 2 mg Tablet in blood and may affect the heart rhythm. Seek immediate medical attention in case of any symptoms such as an irregular heartbeat, chest tightness, blurred vision, or nausea.
Consumption of grapefruit or grapefruit juice is not recommended during treatment with this medicine. Combined use may increase the levels of Mozep 2 mg Tablet in blood and may affect the heart rhythm. Seek immediate medical attention in case of any symptoms such as an irregular heartbeat, chest tightness, fainting, shortness of breath, blurred vision, or nausea.
Lab interactions
Information not available.
Take Mozep 2 mg Tablet exactly as instructed by the doctor. Do not take larger amounts than prescribed. Seek emergency medical treatment in case of any severe side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Mozep 2 mg Tablet works by blocking the action of certain specific chemicals in the brain. This helps in preventing abnormal excitement in the brain and relieving the symptoms of Tourette's syndrome.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Miscellaneous antipsychotic agents

Schedule

Schedule H

[Internet]. 2017 [cited 21 August 2017]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/017473s041lbl.pdf

DailyMed - PIMOZIDE - pimozide tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 21 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=70b079e2-a1f7-4a93-8685-d60a4d7c1280

Pimozide - DrugBank [Internet]. Drugbank.ca. 2017 [cited 21 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB01100

Pimozide: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 21 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a686018.html

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 21 August 2017]. Available from:

http://www.tga.gov.au/prescribing-medicines-pregnancy-database

TOXNET [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 21 August 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~MTvRnb:1
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