Moxonidine

Description

Moxonidine is used alone or in a combination with other medicines for the treatment of high blood pressure. It is not recommended for use in patients less than 18 years of age.

Side effects

Major & minor side effects for Moxonidine

  • Sleep disturbances
  • Diarrhea
  • Nausea or Vomiting
  • Rash
  • Back pain
  • Slow heart rate
  • Anxiety
  • Dizziness
  • Headache
  • Dry mouth

Uses of Moxonidine

What is it prescribed for?

  • Hypertension
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed within 30 minutes to 3 hours of administration of the dose.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to moxonidine or any other inactive ingredients present along with it.

Sick sinus syndrome

This medicine is not recommended for use in patients suffering from sick sinus syndrome due to the increased risk of worsening of the patient's condition.

Atrioventricular Block

This medicine is not recommended for use in patients suffering from a second- or third-degree atrioventricular block due to the increased risk of worsening of the patient's condition.

Bradycardia

This medicine is not recommended for use in patients with bradycardia (heart rate < 50 beats/minute) due to the increased risk of worsening of the patient's condition.

Malignant arrhythmias

This medicine is not recommended for use in patients suffering from malignant arrhythmias due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.
General warnings

Atrioventricular Block

This medicine should be used with caution in patients with a first-degree atrioventricular block due to the increased risk of worsening of the patient's condition. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Renal impairment

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Regular monitoring of kidney function tests is necessary while using this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Driving or Operating machinery

Use of this medicine may cause symptoms such as dizziness, drowsiness, fainting, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Use in Pediatrics

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Cardiac insufficiency

This medicine should be used with extreme caution in patients suffering from a cardiac insufficiency due to the increased risk of worsening of the patient's condition. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Drug Withdrawal

Abrupt discontinuation of this medicine may cause rebound hypertension and side effects such as nervousness, agitation, headache, etc. in some patients. A gradual dose reduction over a period of days to up to 2 weeks may be necessary to avoid these reactions.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Tricyclic Antidepressants

Tolazoline

Benzodiazepines

Other antihypertensive agents

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food, as advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor; an abrupt withdrawal may result in rebound high blood pressure as well as other side effects.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine lowers the blood pressure by reducing the heart rate and relaxing the blood vessels.
Legal Status

Approved

Unknown

Unknown

Approved

Classification

Category

Antiadrenergic agents, centrally acting

Schedule

Schedule H

[Internet]. Db.cbg-meb.nl. 2018 [cited 27 July 2018]. Available from:

https://db.cbg-meb.nl/mri/pil/nlh-0402-001-002-003.pdf

Moxonidine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 27 July 2018]. Available from:

https://www.drugbank.ca/drugs/DB09242

Moxonidine 0.2 mg Film-coated Tablets - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 27 July 2018]. Available from:

https://www.medicines.org.uk/emc/product/8728/smpc#

TGA Business Services [Internet]. Ebs.tga.gov.au. 2018 [cited 27 July 2018]. Available from:

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2018-PI-02060-1

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Information on this page was last updated on 27 Aug 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.