Mometasone is a medicine available in topical forms (cream/ointment/gel/lotion) and as nasal sprays. The topical forms are used to treat skin conditions such as psoriasis (itchy skin with red scaly patches), eczema (thick, dry and itchy skin), and dermatitis (skin irritation). Mometasone nasal spray is used to prevent and relieve symptoms of hay fever and other allergies such as sneezing, runny, stuffy, or itchy nose. It is also used to treat nasal polyps (painless growth or swelling in the nose or sinuses). It works by blocking the release of chemical substances in your body. Mometasone nasal spray shows side effects like headache, nose/throat irritation, blood in the mucous, unexplained nosebleed, etc. Mometasone topical forms may show side effects like burning sensation, irritation, itching, and redness at the site of application. Inform your doctor if these side effects persist or become severe. Mometasone is not recommended if you are allergic to it. Inform your doctor if you have any other medical conditions or taking any other medicines. Consult your doctor if you are pregnant or are breastfeeding before using this medicine.

Side effects

Major & minor side effects for Mometasone

  • Headache
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Bleeding and irritation of nose
  • Blood in the mucous
  • Fever or chills
  • Burning, itching, and irritation of the skin

Uses of Mometasone

What is it prescribed for?

  • Allergic rhinitis
  • Nasal polyps
  • Skin Conditions
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Commonly asked questions

  • Onset of action
    The time required for Mometasone to show its action is not clinically established.
  • Duration of effect
    The time duration for which Mometasone remains effective is in your body is not known.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported for Mometasone.
  • Usage in pregnancy?
    Mometasone is not recommended to be used in pregnancy. Hence, consult your doctor if you are pregnant.
  • Usage while breast-feeding?
    Mometasone may be used with caution while breastfeeding. Consult your doctor if you are breastfeeding before using this medicine.


Mometasone is not recommended for use if you are allergic to it. Serious allergic reactions to this medicine are rare. However, seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Recent nasal surgery

If you have recently had nasal surgery, avoid using Mometasone nasal spray as it may decrease immune activity at the site of surgery, increasing the risk of infection and delaying wound healing. Consult your doctor if you have a nose injury or ulcer of the septum (wall dividing the nostrils).
Warnings for special population


Mometasone is not recommended to be used in pregnancy. Hence, consult your doctor if you are pregnant.


Mometasone may be used with caution while breastfeeding. Consult your doctor if you are breastfeeding before using this medicine.
General warnings

Nosebleed and nasal ulceration

Mometasone nasal spray may cause nose bleeding and nasal ulcerations (sores in the nose). Consult your doctor immediately if you experience such conditions. Your doctor may suggest an alternative medicine based on your condition.

Other medicines

Mometasone may interact with other medicines and cause undesired effects. Hence, inform your doctor if you are using any other medicines before beginning treatment with Mometasone.

External use only

Mometasone is recommended for external use only. Avoid contact with the eyes and mouth.

Missed Dose

Use/apply the missed dose of Mometasone as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.


Topical forms: An overdose of Mometasone is not likely to cause severe symptoms unless it is applied for a prolonged period in large amounts. However, ingestion of this medicine may cause harm and immediate medical intervention may be required. Nasal Spray: Never use more than the prescribed dose. Consult your doctor in case of an overdose of Mometasone.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol


Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.


Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine




Disease interactions


Hyperadrenocorticism is a condition that occurs due to high levels of cortisol hormones (a chemical substance that helps your body respond to stress, regulate blood sugar, and fight infections) in the body. Mometasone should be used with caution as it may occasionally cause or worsen hyperadrenocorticism if applied over a large area for a prolonged time.


Prolonged use of a high dose of Mometasone may suppress the activity of your immune system. Hence, this medicine should be used with caution as it may increase the risk of infections or worsen your condition if you have an infection.

Ocular Toxicities

Rarely, Mometasone may increase the intraocular pressure (high pressure inside the eye caused by an imbalance in the production and drainage of fluid in the eye) and cause glaucoma (a condition where the pressure within the eyeballs is abnormally high that can damage the optic nerve and lead to loss of vision). Inform your doctor if you experience any vision problems.
Food interactions
Information not available.
Lab interactions
Information not available.
Use Mometasone nasal spray as instructed by your doctor. For topical forms, apply a thin layer of Mometasone to the affected area of the skin and spread evenly. Avoid using more or less than the prescribed dose. Avoid discontinuation of this medicine without consulting your doctor.

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Mometasone inhibits the release of certain chemicals in your body.
Legal Status







Nasal steroids, Topical steroids


Schedule H 2021. DailyMed - MOMETASONE FUROATE- mometasone furoate cream. [online] Available at: < [Accessed 23 March 2021].> 2021. Mometasone. [online] Available at: < [Accessed 23 March 2021].>

Drugs, H., 2021. Mometasone Nasal Spray: MedlinePlus Drug Information. [online] Available at: < [Accessed 23 March 2021].> 2021. Mometasone Furoate 1mg/g Cream - Patient Information Leaflet (PIL) - (emc). [online] Available at: < [Accessed 24 September 2021].>

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Information on this page was last updated on 19 Nov 2021


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