Molindone

Description

Molindone is an antipsychotic that is used for the treatment of schizophrenia, a brain disorder characterized by delusions, hallucinations, reduced speaking, etc.

Side effects

Major & minor side effects for Molindone

  • Drowsiness
  • Blurred vision
  • Constipation
  • Dry mouth
  • Nausea or Vomiting
  • Headache and dizziness
  • Unsteadiness
  • Skin rash, hives, or itching

Uses of Molindone

What is it prescribed for?

  • Schizophrenia
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects such as dizziness, difficulty in concentration, impaired judgment, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Molindone or any other inactive ingredient present along with the formulation.

Severe central nervous system depression

This medicine is not recommended for use in patients with severe central nervous system depression due to an increased risk of serious adverse effects.

Coma

This medicine is not recommended for use in comatose patients due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Kidney impairment

This medicine should be used with caution in patients suffering from kidney impairment due to the increased risk of adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver impairment

This medicine should be used with extreme caution in patients suffering from liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Breast cancer

This medicine may increase the prolactin levels in the body and hence should be used with extreme caution in patients with existing or suspected malignancy of the breast. Report any unusual symptoms to the doctor immediately. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or operating machinery

This medicine may cause drowsiness, blurred vision, dizziness, etc. in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms.

Neutropenia

This medicine should be used with extreme caution in patients suffering from neutropenia (a low count of a type of white blood cell called neutrophils) due to the increased risk of severe adverse effects. Close monitoring of complete blood count and signs or symptoms of infection is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition. It is not recommended for use in patients with severe neutropenia.

Intestinal obstruction

This medicine should be used with extreme caution in patients suffering from intestinal obstruction due to the increased risk of severe adverse effects. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe side effects such as dizziness, difficulty in concentration, impaired judgment, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Tramadol

Levodopa

Bupropion

Furosemide

Diltiazem

Disease interactions

Dementia

This medicine is not recommended for use in patients with dementia-related psychosis due to the increased risk of heart failure, pneumonia, death, etc. This risk is especially high in elderly patients. Replacement with a suitable alternative should be considered under your doctor's supervision.

Tardive Dyskinesia

This medicine should be used with extreme caution in patients with tardive dyskinesia, a condition of involuntary repetitive body movements, since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate patient/caregiver education, close monitoring of the patient's condition, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Seizures

This medicine should be used with caution in patients with seizure disorders or central nervous system abnormalities due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Neuroleptic Malignant Syndrome (NMS)

This medicine should be used with extreme caution in patients with a known history of a neuroleptic malignant syndrome (NMS) due to the increased risk of worsening of the patient's condition. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Parkinson's disease

This medicine may cause pseudo-parkinsonian symptoms such as slow body movements, tremors, pill-rolling motion, postural abnormalities, and gait abnormalities. Hence, this medicine should be used with caution in patients with Parkinson's disease. Report any worsening of the condition to the doctor on priority. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Cardiovascular diseases

This medicine should be used with extreme caution in patients suffering from cardiovascular diseases due to the increased risk of severe adverse effects. Close monitoring of heart function and blood pressure levels is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking this medicine before completion of the course/without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by blocking the action of certain specific chemicals in the brain. This helps in preventing abnormal excitement in the brain and relieving psychotic symptoms.
Legal Status

Approved

Approved

Unknown

Unknown

Classification

Category

Miscellaneous antipsychotic agents

Schedule

Schedule H

DailyMed - Molindone Hydrochloride tablet [Internet]. Dailymed.nlm.nih.gov. 2020 [cited 4 May 2020]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1275e92f-9573-4d0c-8e77-1c9ac47696d2

Molindone - DrugBank [Internet]. Drugbank.ca. 2020 [cited 4 May 2020]. Available from:

https://www.drugbank.ca/drugs/DB01618

[Internet]. Accessdata.fda.gov. 2020 [cited 4 May 2020]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/017111s062lbl.pdf

Molindone: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 4 May 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a682238.html

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Information on this page was last updated on 15 May 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.