Molgramostim

Description

Molgramostim is a medicine used for improving the white blood cell count in patients receiving chemotherapy or who underwent a bone marrow transplant. It stimulates the growth of white blood cells and helps in decreasing the chances of infection.

Side effects

Major & minor side effects for Molgramostim

  • Severe allergic reaction
  • Nausea and Vomiting
  • Chest pain
  • Headache
  • Muscle and joint pain
  • Fever
  • Diarrhea

Uses of Molgramostim

What is it prescribed for?

  • Neutropenia
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Molgramostim or any other inactive ingredients present along with it.

Myeloid malignancies

This medicine is not recommended for use in patients with myeloid malignancies due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Severe allergic reactions

This medicine may cause severe allergic reactions and injection site reactions. In case of any such reactions, treatment should be discontinued and appropriate medical therapy should be instituted immediately.

Liver Disease

This medicine should be used with caution in patients with liver disease due to the increased risk of adverse effects. Regular monitoring of the liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Impairment

This medicine should be used with caution in patients with kidney disease due to the increased risk of adverse effects. Regular monitoring of the kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Monitoring parameters

The blood cells count and platelet count should be monitored frequently while treating with this medicine. The spleen size should also need to be monitored as there might be chances for enlargement of the spleen.

Other medicines

Molgramostim may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Driving or Operating machinery

Use of this medicine may cause dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience dizziness during the treatment with this medicine.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Cyclophosphamide

Vincristine

Vinblastine

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Continuous evaluation of blood cell count, platelet count, liver function, kidney function, and spleen size is recommended in patients undergoing this therapy.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by promoting the formation of new white blood cells and improves immunity.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Immunostimulants, Granulocyte-macrophage colony-stimulating factor (GM-CSF)

Schedule

Schedule H

Molgramostim - DrugBank [Internet]. Drugbank.ca. 2018 [cited 27 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB12525

Molgramostim - an overview | ScienceDirect Topics [Internet]. Sciencedirect.com. 2018 [cited 27 December 2018]. Available from:

https://www.sciencedirect.com/topics/immunology-and-microbiology/molgramostim

[Internet]. Vademecum.es. 2018 [cited 27 December 2018]. Available from:

https://www.vademecum.es/principios-activos-molgramostim-l03aa03

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Information on this page was last updated on 25 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.