Description
Mofloren-Unims 0.5% Infusion is a broad-spectrum antibiotic that is used to treat a variety of bacterial infections such as bronchitis, pneumonia, intraabdominal infections, etc. This medicine should be used with caution in the elderly population since it increases the risk of tendinitis and tendon rupture. It is not recommended for use in patients less than 18 years of age.
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Side effects
Major & minor side effects for Mofloren-Unims 0.5% Infusion
- Abdominal pain
- Blurred vision
- Bone pain
- Dark or clay colored stools
- Dizziness
- Irregular heartbeat
- Headache
- Severe sunburn
- Acid or sour stomach
- Nervousness
- White patches in the mouth or on the tongue
Uses of Mofloren-Unims 0.5% Infusion
What is it prescribed for?
- Pneumonia
- Skin and Structure Infection
- Intra-abdominal Infections
- Bronchitis
- Plague
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Concerns
Commonly asked questions
- How long does it take for this medicine to take effect?The amount of time required for this medicine to show its action is not clinically established.
- How long do the effects of this medicine last?The amount of time for which this medicine remains active in the body is not clinically established.
- Is it safe to consume alcohol while taking this medicine?Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
- Is this a habit forming medicine?No habit-forming tendencies were reported.
- Can this medicine be taken during pregnancy?This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
- Can this medicine be taken while breast-feeding?This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects such as diarrhea, diaper rash, etc. Your doctor may prescribe a safer alternative based on your clinical condition.
Allergy
This medicine is not recommended for use in patients with a known allergy to moxifloxacin, any other quinolones, or any other inactive ingredients present along with it.
Tendinitis or tendon rupture
This medicine is not recommended for use in patients with a known history of tendon rupture or tendinitis (a condition in which the tissue connecting muscles to the bones becomes inflamed) due to the increased risk of worsening of the patient's condition.
Myasthenia gravis
This medicine is not recommended for use in patients with a known history or family history of myasthenia gravis (weakness and rapid fatigue of muscles under voluntary control) due to the increased risk of worsening of the patient's condition.
Severe Hepatic impairment
This medicine is not recommended for use in patients with severe liver impairment (Child-Pugh score: C) and in patients with transaminase levels greater than 5 times the upper limits of normal since the safety and efficacy of use are not clinically established.
Warnings for special population
Pregnancy
This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
Breast-feeding
This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine. If the medicine is used, the infant should be monitored closely for any undesired side effects such as diarrhea, diaper rash, etc. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings
Tendinitis and tendon rupture
Use of this medicine will increase the risk of tendinitis or tendon rupture during the treatment and for several months after the treatment. This may affect your shoulders, hands, ankles, or other parts of your body. You are at a higher risk if you are more than 60 years of age or if you have undergone a transplant of kidney, heart, or lung. You are also at a higher risk if you are on corticosteroids such as dexamethasone, methylprednisolone, or prednisone. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Drug-resistance
Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing benefits and may even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.
Driving or Operating machinery
Use of this medicine may rarely cause symptoms such as blurred vision, drowsiness, dizziness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.
Pediatric use
This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.
Clostridium difficle-associated diarrhea
Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in such cases.
Impaired liver function
This medicine should be used with caution in patients with a known history of liver impairment due to the increased risk of severe adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Intravenous Administration
This medicine is not recommended for administration as a bolus/IV push. It should be administered only by a slow intravenous infusion over a period of 60 minutes.
Missed Dose
Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.
Overdose
Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol
Description
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Instructions
Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Escitalopram
Ethinyl Estradiol
Corticosteroids
Quinidine
Aspirin
Antidiabetic medicines
Disease interactions
Central nervous system disorders
This medicine should be used with extreme caution in patients with a history of seizure disorder and other central nervous system abnormalities since it may worsen the patient's condition. Report any incidence of tremors, restlessness, anxiety, confusion, hallucinations, etc., to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient. It is advisable to avoid using caffeine-containing products such as coffee, chocolates, energy drinks, etc. during treatment with this medicine since such products may further stimulate the central nervous system and worsen the patient's condition.
QT Prolongation
This medicine should be used with extreme caution in patients with a history of QT prolongation due to the increased risk of worsening of the patient's condition. This risk is especially higher in patients with heart diseases or electrolyte disturbances and elderly patients. Report any incidence of discomfort in the chest, heart palpitations, etc., to the doctor on priority. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Gastrointestinal Diseases
This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine. Report any undesirable side effects to the doctor promptly.
Miscelleneous
How it works
This medicine works by inhibiting an enzyme required for the bacterial DNA to replicate. This blocks the multiplication and growth and results in the eventual death of the bacteria.
Legal Status
Classification
Category
Quinolones
Schedule
Schedule H
MOXICIP Infusion [Internet]. CiplaMed. 2018 [cited 29 June 2018]. Available from:
Moxifloxacin Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 29 June 2018]. Available from:
[Internet]. Accessdata.fda.gov. 2018 [cited 29 June 2018]. Available from:
Avelox 400 mg/250 ml solution for infusion - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 29 June 2018]. Available from:
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Information on this page was last updated on 29 Jun 2018
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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.