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Mobirof 12.5 MG Tablet DT

Manufactured by: Shreya Life Sciences Pvt. Ltd.
Composition: Rofecoxib
Prescription Required: Yes
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Description

Mobirof 12.5 MG Tablet DT is a medicine belonging to the group Non-steroidal anti-inflammatory drugs. It is used for relieving mild to moderate pain and swelling of joints and muscles. However, the use of this medicine has been associated with adverse effect on heart and should be used with caution.

Side effects

Major & minor side effects for Mobirof 12.5 MG Tablet DT

  • Headache
  • Nausea or Vomiting
  • Swelling of face, lips, eyelids, tongue, hands and feet severe
  • Severe stomach achesevere
  • Blurred vision
  • Hives and wheezingsevere
  • Heart attacksevere
  • Kidney failuresevere
  • Liver diseasesevere
  • Urinary tract infection
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Mobirof 12.5 MG Tablet DT

Onset of action

The effect of this medicine can be observed within 1-3 hours of administration.

Duration of effect

The effect of this medicine lasts for an average duration of 16-20 hours.

Safe with alcohol?

moderate
Restrict or minimize the use of alcohol while taking this medicine. Report any instances of heartburn or stomach discomfort like severe cramps and pain to the doctor on priority.

Is it habit forming?

No habit forming tendencies were reported.

Usage in pregnancy?

This medicine is not recommended for use if you are pregnant or planning a pregnancy in near future. Your doctor may prescribe a safer alternative if the use of a painkiller is absolutely necessary.

Usage while breast-feeding?

This medicine is not recommended for use if you are breastfeeding. Your doctor may prescribe a safer alternative if the use of a painkiller is absolutely necessary.

What is it prescribed for?

Uses of Mobirof 12.5 MG Tablet DT

  • Osteoarthritis

    Mobirof 12.5 MG Tablet DT is used to treat pain and swelling associated with Osteoarthritis.
  • Rheumatoid Arthritis

    Mobirof 12.5 MG Tablet DT is used for relieving swelling, stiffness, and pain of joints caused due to Rheumatoid Arthritis.
  • Ankylosing Spondylitis

    Mobirof 12.5 MG Tablet DT is also used for the symptomatic treatment of Ankylosing spondylitis. This disease causes swelling of the spine and large joints.

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When not to use?

Contraindications of Mobirof 12.5 MG Tablet DT

  • Allergy

    This medicine is not recommended for use if you are allergic to it or any other component of the medicine.
  • Peptic Ulcer

    This medicine is not recommended if you have peptic ulcer or other conditions that cause swelling and bleeding of the stomach. It could cause severe swelling and bleeding in the stomach, colon, and anus as well.
  • Heart diseases

    This medicine is not recommended for use in patients having a history of heart conditions. The risk of fatal adverse effects are even higher if you have an active condition like heart block, rhythm disorder etc.

Dosage

  • Missed Dose

    Take the missed dose as soon as you remember. The missed dose should be skipped if it is almost time for the next scheduled dose.
  • Overdose

    Contact your doctor immediately if an overdose is suspected. Symptoms of overdose may include skin rashes, confusion, chest pain, blurred vision etc.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcoholmoderate

  • Description

    - Use of alcohol while taking this medicine can cause some very severe side effects in the stomach and intestine.
  • Instructions

    - Restrict or minimize the use of alcohol while taking this medicine. Report any instances of heartburn or stomach discomfort like severe cramps and pain to the doctor on priority.

Interaction with Medicine

  • Lithiumsevere
  • Ramiprilsevere
  • Warfarinsevere
  • Ethinyl Estradiolmoderate
  • Primaquinesevere

Disease interactions

  • Heart Disease

    severe
    This medicine should be used with extreme caution if you are suffering from any heart-related conditions. Report the incidence of stroke, heart attack or heart failure to the doctor before receiving this medication. Your doctor may prescribe a more suitable medicine based on the severity of the condition.
  • Liver Disease

    severe
    This medicine should be used with extreme caution in patients having an active liver disease especially if the liver function is severely impaired. Suitable dose adjustment and safety monitoring may be required in such cases.
  • Gastro-intestinal disease

    severe
    This medicine should be used with caution if you have any disease of the stomach or intestine. The risk of worsening of symptoms is very high while using this medicine. Report any such instance, whether historic or active, to the doctor.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Mobirof 12.5 MG Tablet DT as prescribed by the doctor. Do not take this medicine in larger or smaller quantities than prescribed. It can be taken with or without food. An adequate amount of water should be consumed while taking this medication.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is not recommended for use if you are pregnant or planning a pregnancy in near future. Your doctor may prescribe a safer alternative if the use of a painkiller is absolutely necessary.
  • Breast-feeding

    - This medicine is not recommended for use if you are breastfeeding. Your doctor may prescribe a safer alternative if the use of a painkiller is absolutely necessary.

General warnings

  • Heart disease and fatality

    - Mobirof 12.5 MG Tablet DT has been associated with severe to fatal adverse effects on the heart and hence should be used with extreme caution. It should not be used if you have moderate to severe heart block, angina, heart attack etc.
  • Stomach ulcer and bleeding

    - Use of this medicine can cause moderate to severe ulcer in the stomach. Report any such instance to the doctor immediately.
  • Other medicine

    - This medicine is known to interact with a large number of other medicine that you might possibly be taking. Report the use of all medications including supplements and herbs to the doctor. Do not stop the use of any medicine without consulting your doctor.
  • Pediatric use

    - This medicine is not recommended for use by children below 16 years.
  • Kidney impairment

    - This medicine can cause some serious side effects on the kidney. Report any such instance to the doctor on priority.

Other details

  • Can be taken with or without food, as advised by your doctor
  • To be taken as instructed by doctor
  • May cause sleepiness

How it works

This medicine works by reducing the formation of certain substances in the body that causes pain and swelling.

Legal Status

Banned
Banned
Unknown
Unknown

Classification

Category
Nonsteroidal anti-inflammatory agents
Schedule
Schedule H

References

  • [Internet]. 2017 [cited 21 March 2017]. Available from: https://www.merck.com/product/usa/pi_circulars/v/vioxx/vioxx_ppi.pdf
  • [Internet]. 2017 [cited 21 March 2017]. Available from: http://www.accessdata.fda.gov/drugsatfda_docs/label/2004/21647_vioxx_lbl.pdf
  • [Internet]. 2017 [cited 21 March 2017]. Available from: http://www.accessdata.fda.gov/drugsatfda_docs/nda/2003/021042_S024_VIOXXTM_PRNTLBL.pdf
  • [Internet]. 2017 [cited 21 March 2017]. Available from: https://www.medicines.org.uk/emc/PIL.4079.latest.pdf
  • Rofecoxib | C17H14O4S - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 21 March 2017]. Available from: https://pubchem.ncbi.nlm.nih.gov/compound/5090#section=Top

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Information on this page was last updated on 16 Nov 2017

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.