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Mitotax 250 MG Injection

Manufactured by: Dr. Reddys Laboratories Ltd.
Composition: Paclitaxel
Prescription Required: Yes
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Description

Mitotax 250 MG Injection is an anticancer agent which is used in the treatment of various cancers of the female reproductive system, lungs, and breast. It should be used under the supervision of a qualified physician. Close monitoring of blood cell count is necessary while receiving this medication.

Side effects

Major & minor side effects for Mitotax 250 MG Injection

  • Neutropeniasevere
  • Difficult or painful urinationsevere
  • Dizziness when getting up suddenly from a sitting positionsevere
  • Fever and chillssevere
  • Pale skinsevere
  • Allergic Skin Reactionsevere
  • Mouth ulcerssevere
  • Difficulty in breathingsevere
  • Chest discomfortsevere
  • Swelling and redness at the injection site
  • Diarrhea
  • Hair loss or thinning of the hair
  • Nausea and Vomiting
  • Joint pain
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Mitotax 250 MG Injection

Onset of action

The peak effect of this medicine can be observed in less than an hour.

Duration of effect

The effect of this medicine lasts for an average duration of 27 hours.

Safe with alcohol?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is it habit forming?

No habit forming tendencies were reported.

Usage in pregnancy?

This medicine is not recommended for pregnant women.

Usage while breast-feeding?

This medicine is not recommended in breastfeeding women.

Substitutes

List of substitutes for Mitotax 250 MG Injection

Below is the list of medicines, which have the same composition, strength and form as Mitotax 250 MG Injection, and hence can be used as its substitute.
Altaxel 250 MG Injection
Alkem Laboratories Ltd.

What is it prescribed for?

Uses of Mitotax 250 MG Injection

  • Ovarian Cancer

    Mitotax 250 MG Injection is used in the treatment of cancer that affects the female reproductive system.
  • Breast Cancer

    Mitotax 250 MG Injection is used in the treatment of breast cancer.
  • Non-Small Cell Lung Cancer

    Mitotax 250 MG Injection is used in the treatment of Non-Small Cell Lung Cancer which is a type of cancer that affects the lungs.
  • Kaposi's Sarcoma

    Mitotax 250 MG Injection is used in the treatment of Kaposi's Sarcoma which is a type of cancer that develops under the skin in the lining of mouth, nose, and throat.

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When not to use?

Contraindications of Mitotax 250 MG Injection

  • Allergy

    Not recommended in the patients with known allergy to Mitotax 250 MG Injection.
  • Neutrophils count

    Not recommended in the patients with neutrophils count less than 1,500 cells/mm3

Dosage

  • Missed Dose

    It is advised not to miss any dose. If you missed any dose, you should contact your doctor immediately.
  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

  • Description

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Instructions

    - Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

  • Clozapinesevere
  • Diltiazemmoderate
  • Atorvastatinmoderate
  • Live vaccinessevere

Disease interactions

  • cardiac conduction abnormalities

    severe
    This medicine is known to cause serious heart conduction abnormalities. Inform the doctor if you have any heart diseases. Close monitoring of low blood pressure and decreased heartbeat is necessary.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

This medicine is given in multiple cycles. It is important to receive the every scheduled dose and make a note of next scheduled dose. Close monitoring of blood cells count especially, neutrophils is necessary.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is not recommended for pregnant women.
  • Breast-feeding

    - This medicine is not recommended in breastfeeding women.

General warnings

  • Blood cell count

    - This medicine may lower the white blood cell count (neutrophils). Close monitoring of blood cell count is necessary. Do not start the treatment if the neutrophils count is less than 1500 cells/mm3.
  • Infections

    - The chances of occurring infections are more in the patients receiving this medicine. Hold the chemotherapy and start with the broad-spectrum antibiotics if there are any signs and symptoms of fever. Close monitoring of the body temperature and the blood cell count is necessary.
  • Allergy

    - This medicine may cause serious skin reactions. Discontinue the treatment if any symptoms of allergy appear and do not restart.
  • Liver injury

    - This medicine is not recommended in the patients with the liver injury. The concentration of this medicine may increase in these patients. The baseline of the liver function tests should be obtained before starting the treatment.
  • Use in men

    - Men should not plan for a child when receiving this medicine.

Other details

  • Usage does not depend on food timings
  • To be taken as instructed by doctor
  • May cause sleepiness

How it works

It works by stopping the growth of cells by acting on microtubules that provide structure and movement of the cells.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
Antineoplastics
Schedule
Schedule H

References

  • [Internet]. 2017 [cited 14 April 2017]. Available from: https://www.medicines.org.uk/emc/medicine/24064
  • DailyMed - Paclitaxel injection [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 14 April 2017]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9ffd3e34-537f-4f65-b00e-57c25bab3b01
  • Paclitaxel Injection: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 14 April 2017]. Available from: https://medlineplus.gov/druginfo/meds/a607070.html
  • Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 14 April 2017]. Available from: https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname
  • [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 14 April 2017]. Available from: https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~TyXUba:1

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Information on this page was last updated on 16 Nov 2017

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.