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Migranil EC Tablet

Manufactured byINGA LABORATORIES PVT LTD
ContainsErgotamine (1 mg) + Caffeine (100 mg)
Description

Migranil EC Tablet is a combination medicine which may be used to prevent or treat migraine headache. This medicine is not recommended for regular tension headaches.

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Side effects

Major & minor side effects for Migranil EC Tablet

  • Chest pain
  • Irregular heartbeat
  • Dizziness
  • Pain or swelling in the legs
  • Muscle cramps
  • Itching
  • Burning or tingling sensation
  • Nausea and Vomiting
  • Numbness
  • Stomach pain

Uses of Migranil EC Tablet

What is it prescribed for?

  • Migraine
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains effective in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to ergotamine, caffeine or any other inactive ingredients present along with this formulation.

CYP3A4 inhibitors

This medicine is not recommended for use in patients taking CYP3A4 inhibitors such as ritonavir, erythromycin, ketoconazole, etc. due to the increased risk of severe and life-threatening adverse effects.

Hypertension

This medicine is not recommended for use in patients with a known history of hypertension due to the increased risk of worsening of the patient's condition.

Kidney impairment

This medicine is not recommended for use in patients with a known history of kidney impairment due to the increased risk of worsening of the patient's condition.

Liver impairment

This medicine is not recommended for use in patients with a known history of liver impairment due to the increased risk of worsening of the patient's condition.

Coronary heart disease

This medicine is not recommended for use in patients with a known history of coronary heart disease due to the increased risk of worsening of the patient's condition.

Sepsis

This medicine is not recommended for use in patients with a known history of septicemia (Sepsis) due to the increased risk of worsening of the patient's condition.

Peripheral vascular disease

This medicine is not recommended for use in patients with a known history of Peripheral vascular disease due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Use in children

This medicine is not recommended for use in children and adolescents since the safety and efficacy of use are not clinically established.

Sports

Athletes are advised not to indulge in certain sports while using this medicine. Archery, racing, shooting and other high-risk sports should be avoided. Sportspersons should refer to the list of medicines published by the World Anti-Doping Agency (WADA) which are not to be taken while participating in specific sports events.

Missed Dose

Since this medicine is usually taken as when required, the likelihood of missing a dose is very low.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Erythromycin

Fluoxetine

Fluvoxamine

Sertraline

Nefazodone

Trazodone

Atenolol

Carvedilol

Venlafaxine

Disease interactions

Peptic ulcer disease

This medicine should be used with extreme caution in patients peptic ulcer disease due to the increased risk of worsening the patient’s condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Psychiatric Conditions

This medicine should be used with extreme caution in patients with a history of psychosis, depression, mania, or bipolar disorder due to the increased risk of worsening the patient’s conditions. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Seizure disorders

This medicine should be used with extreme caution in patients with a history of seizures due to the increased risk of worsening the patient’s conditions. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Gastroesophageal reflux

This medicine should be used with extreme caution in patients with a history of Gastroesophageal reflux disease due to the increased risk of worsening the patient’s conditions. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of adverse effects such as dizziness, muscle pain, fever and chills, headache, swelling of hands and feet, vomiting, skin rash, etc.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Do not take this medicine for longer durations than recommended. Report any unusual symptoms to the doctor immediately. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Effect on sleep is not established

How it works
Ergotamine constricts the blood vessels in the head. This reduces the blood flow in the head and decreases the symptoms of a migraine headache. Caffeine may aid in the body’s absorption of ergotamine and significantly improves its efficacy.
Legal Status

Unknown

Approved

Unknown

Unknown

Classification

Category

Antimigraine agents

Schedule

Schedule H

Ergotamine Tartrate and Caffeine Tablets, USP 1 mg/100 mg [Internet]. Dailymed.nlm.nih.gov. 2019 [cited 24 May 2019]. Available from:

https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=41f88ae7-c124-5b9c-e054-00144ff88e88&type=display

Ergotamine: DrugBank [Internet]. Drugbank.ca. 2017 [cited 30 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00696
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Information on this page was last updated on 15 Nov 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.