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Mignar MF (500/25 mg) Tablet

Manufactured byGlenmark Pharmaceuticals Ltd.
ContainsMetformin (500 mg) + Miglitol (25 mg)
Description
Mignar MF (500/25 mg) Tablet is a combination medicine used to control high blood glucose levels in patients with type 2 diabetes mellitus. Patients are advised to maintain a strict exercise and diet regimen along with this medicine to get the best possible effect.

Side effects

Major & minor side effects for Mignar MF (500/25 mg) Tablet

  • Abdominal pain or bloating
  • Diarrhea
  • Skin rash
  • Lactic Acidosis
  • Weakness
  • Nausea and vomiting
  • Loss of appetite
  • Difficult or painful urination
  • Fever and chills

Uses of Mignar MF (500/25 mg) Tablet

What is it prescribed for?

  • Type II Diabetes Mellitus
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • How long do the effects of this medicine last?
    The time until which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to miglitol, metformin, or any other inactive ingredients present along with these medicines.

Diabetic ketoacidosis

This medicine is not recommended for use in patients with diabetic ketoacidosis due to the increased risk of worsening of the patient's condition.

Inflammatory bowel disease

This medicine is not recommended for use in patients with a known history of Inflammatory bowel disease due to the increased risk of severe adverse effects.

Intestinal Obstruction

This medicine is not recommended for use in patients with a known history of Intestinal Obstruction since it may worsen the patient's condition.

Metabolic Acidosis

This medicine is not recommended for use in patients with metabolic acidosis since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Hypoglycemia

This medicine may cause hypoglycemia in some patients. This risk is especially higher in patients suffering from kidney diseases, malnourishment, pituitary gland diseases, etc. Close monitoring of blood glucose levels is recommended for such patients. Appropriate dose adjustments may be required based on the clinical condition. Your doctor may advise you to carry a sugar candy to counteract the effects of low blood sugar levels (hypoglycemia).

Gastrointestinal disease

This medicine is not recommended for use in patients with any gastrointestinal diseases like inflammatory bowel disease, colonic ulceration, partial intestinal obstruction, or any chronic intestinal disease. It is advised that you should inform the doctor about all your medical conditions before starting treatment with this medicine.

Lactic Acidosis

This medicine may cause lactic acidosis, which may be fatal, in some patients. This risk is especially higher in patients suffering from heart diseases, kidney diseases, etc. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be required based on the clinical condition.

Kidney disease

This medicine should be used with caution in patients with a known history of kidney disease due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Stress

Use of this medicine should be discontinued in patients exposed to stressful conditions such as a fever, trauma, surgeries, or accidents since it may not be effective in controlling blood sugar levels in these conditions. Replacement with a suitable alternative should be considered under your doctor's supervision.

Type I diabetes

This medicine is not recommended for use in patients suffering from Type I diabetes since it is not effective in treating such patients.

Diarrhea

This medicine may cause diarrhea when therapy is initiated. In most cases, diarrhea subsides by itself. Contact your doctor if the problem persists for longer durations. Therapy may need to be discontinued in some cases based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.
Interaction with Medicine

Amlodipine

Estradiol

Corticosteroids

Iodinated Contrast Media

Aloe Vera

Furosemide

Gatifloxacin

Disease interactions

Diabetic Ketoacidosis

This medicine is not recommended for use in patients suffering from diabetic ketoacidosis since the risk of adverse effects is significantly high. Replacement with a suitable alternative should be considered under your doctor's supervision.

Gastro-intestinal disease

This medicine is not recommended for use in patients with inflammatory bowel disease or any chronic intestinal disease. An alternative treatment option should be considered based on the clinical condition. It is advised that you should inform the doctor about all your medical conditions before starting treatment with this medicine.

Lactic Acidosis

This medicine may cause lactic acidosis in some patients. This risk is especially higher in patients with kidney diseases, heart diseases, or septicemia. Close monitoring of blood glucose levels, kidney function, heart function, and liver function may be required for such patients based on the clinical condition. Report any symptoms such as fatigue, breathing difficulty, increased sleep, nausea, vomiting, diarrhea, irregular heartbeat, etc. to the doctor immediately. Appropriate corrective measures and discontinuation of therapy may be required in some cases based on the clinical condition.

Vitamin B12 deficiency

This medicine should be used with extreme caution in patients with vitamin B12 deficiency since it may worsen the patient's condition. Appropriate vitamin B12 supplementation and dose adjustments may be required based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as prescribed by the doctor. It is advised to take this medicine just before meals or with meals. Your dose is likely to change over time based on therapeutic response and clinical condition. Regular monitoring of blood sugar levels is recommended during treatment with this medicine. You should always carry a sugar candy with you to counteract unexpected lowering of blood sugar levels. Do not change the dose or duration of use without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Metformin decreases absorption of glucose from the intestines and increases the action of insulin in the body. Miglitol blocks the production of glucose.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Oral anti-diabetic combinations, Combination of oral biguanidies and alpha-glucosidase inhibitors

Schedule

Schedule H

DailyMed - Miglitol tablet, coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 7 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=192e6ed7-9e8c-4772-9e3b-5912a1c63a31

Miglitol - DrugBank [Internet]. Drugbank.ca. 2017 [cited 7 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00491

DailyMed - Metformin hcl tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 1 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2d98aea3-35ba-447a-b88f-a5a20b612b2f
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Information on this page was last updated on 15 Nov 2017

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