Mianserin

Description

Mianserin is an antidepressant medication used in the treatment of patients suffering from depression. This medicine not recommended for use in patients below the 18 years of age.

Side effects

Major & minor side effects for Mianserin

  • Edema
  • Sedation
  • Convulsions (seizures)
  • Decreased blood pressure
  • Abnormal Liver function
  • Weight gain
  • Slow heartbeat

Uses of Mianserin

What is it prescribed for?

  • Major depression
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 3 hours of administration of the dose.
  • Duration of effect
    The amount of time required for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended while receiving this medicine since it may increase the risk of severe adverse effects like sedation, confusion, impaired concentration, and judgment. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to mianserin or any other inactive ingredients present along with it.

Severe liver disease

This medicine is not recommended for use in patients with severe liver diseases due to the increased risk of worsening of the patient's condition.

Mania

This medicine is not recommended for use in patients suffering from mania, a mood disorder characterized by increased irritability, overactivity, etc due to the increased risk of worsening of the patient's condition.

Monoamine oxidase inhibitors (MAOI)

This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between stopping therapy with MAOIs and starting therapy with this medicine.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Use in Children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established.

Driving or Operating machinery

Use of this medicine may cause confusion, difficulty in concentrating, dizziness, etc in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Liver Disease

This medicine should be used with caution in patients suffering from mild to moderate liver diseases due to the increased risk of adverse effects. Regular monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Suicidal Thoughts

This medicine should be used with caution due to the increased risk of suicidal tendencies. Patients should be closely monitored for any change in mood or behavior. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Surgery

Use of this medicine should be reported to your doctor or anesthetic before you undergo a surgery which requires an anesthetic to avoid their interaction.

Heart diseases

This medicine should be used with caution in patients with recent heart block or heart diseases due to the increased risk of severe adverse effects. Appropriate dose adjustments, frequent clinical monitoring, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while receiving this medicine since it may increase the risk of severe adverse effects like sedation, confusion, impaired concentration, and judgment. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and this medicine are used together.
Interaction with Medicine

Antibiotics

Phenytoin

Warfarin

Barbiturates

Moclobemide

Disease interactions

Seizures

This medicine should be used with extreme caution in patients with seizures due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver Disease

This medicine should be used with caution in patients suffering from mild to moderate liver diseases due to the increased risk of adverse effects. Regular monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly advised by the doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
It works by increasing the levels of certain chemical substances in the brain and thus helps in relieving the depressive symptoms.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Antidepressants

Schedule

Schedule H

[Internet]. Medicines.org.au. 2018 [cited 14 December 2018]. Available from:

http://www.medicines.org.au/files/afplumin.pdf

Mianserin [Internet]. 2018 [cited 14 December 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/mianserin#

Mianserin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 14 December 2018]. Available from:

https://www.drugbank.ca/drugs/DB06148

Mianserin 10 mg film-coated tablets - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2018 [cited 14 December 2018]. Available from:

https://www.medicines.org.uk/emc/product/8476/smpc

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Information on this page was last updated on 13 Jun 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.