Metromax Am (5/25 mg) Tablet

Manufactured byAkumentis Healthcare Ltd.
ContainsAmlodipine (5 mg) + Metoprolol (25 mg)
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Description

Metromax Am (5/25 mg) Tablet is a combination medicine used for the treatment of high blood pressure and ischemic heart disease. This medicine is not recommended for use in patients below 18 years of age. Patients are advised to maintain a strict exercise and diet regimen along with this medicine for the best possible effect.

Substitutes

List of substitutes for Metromax Am (5/25 mg) Tablet

Side effects

Major & minor side effects for Metromax Am (5/25 mg) Tablet

  • Chest pain and discomfort
  • Decreased blood pressure
  • Blurred vision
  • Dizziness
  • Shortness of breath
  • Nausea or vomiting
  • Skin rash
  • Swelling of ankles or feet
  • Redness of face, neck, arms and chest
  • Muscle pain
  • Heartburn
  • Acid or sour stomach
  • Stomach pain
  • Anxiety
  • Diarrhea
  • Constipation

Uses of Metromax Am (5/25 mg) Tablet

What is it prescribed for?

  • Hypertension
  • Ischemic heart disease
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • Duration of effect
    This effect of this medicine lasts for an average duration of approximately 24 hours.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, irregular heart rate, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to metoprolol, other beta-blockers, amlodipine, or other calcium channel blockers.

Heart diseases

This medicine is not recommended for use in patients suffering from heart diseases such as a heart block greater than first degree, cardiogenic shock, sick sinus syndrome (without a permanent pacemaker in place), sinus bradycardia, etc. since it may worsen the patient's condition.

Circulatory disorders

This medicine is not recommended for use in patients suffering from blood circulation disorders since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Heart Failure

This medicine should be used with caution in patients suffering from heart diseases due to the increased risk of heart failure. Close monitoring of heart function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Abrupt withdrawal

Abrupt withdrawal of this medicine in patients with ischemic heart diseases may worsen the symptoms of such patients, especially after a prolonged use. The dose of this medicine should be reduced gradually over a period of 1 to 2 weeks before withdrawing therapy.

Major surgery

This medicine should be used with extreme caution in patients undergoing a major surgery due to the increased risk of severe adverse effects. Close monitoring of heart function is recommended for such patients. An appropriate anesthetic agent should be chosen to minimize the interaction as well as side effects.

Pheochromocytoma

This medicine should be administered with caution in patients with pheochromocytoma due to the increased risk of a very high blood pressure. Appropriate corrective measures or replacement with a suitable alternative may be required based on the clinical condition.

Lung diseases

This medicine is not recommended for use in patients suffering from obstructive lung diseases such as bronchial asthma, bronchospasm, or Chronic Obstructive Pulmonary Disease since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Diabetes

This medicine should be used with caution in patients suffering from diabetes due to the increased risk of very low blood sugar levels. Close monitoring of blood sugar levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Hyperthyroidism

This medicine should be administered with caution in patients suffering from hyperthyroidism since it may mask some of the patient's symptoms. Report any unusual symptoms to the doctor immediately. Close monitoring of thyroid hormone levels is recommended for such patient. Replacement with a suitable alternative may be required based on the clinical condition.

Peripheral Vascular Diseases

This medicine should be used with caution in patients suffering from peripheral vascular diseases since it may worsen the patient's condition. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be required in some cases based on the clinical condition.

Other Medicines

This medicine may interact with many other medicines and may cause serious adverse effects. It is advised that you report to the doctor all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Sports

Athletes are advised to avoid participating in high-risk sports such as archery, racing, shooting, etc. during treatment with this medicine. Sportspersons should refer to the list of medicines published by World Anti-Doping Agency to get information about the prohibited substances.

Aortic stenosis

This medicine should be used with extreme caution in patients suffering from aortic stenosis due to the increased risk of a very low blood pressure. Close monitoring of blood pressure is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Pediatric use

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Driving and operating machines

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

The missed dose should be taken as soon as possible. It is advisable to skip the missed dose if it is already time for your next scheduled dose. Do not take extra medicine to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, irregular heart rate, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Carbamazepine

Diltiazem

Itraconazole

Corticosteroids

Rifampicin

Aminophylline

Ergotamine

Disease interactions

Lung disease

This medicine is not recommended for use in patients suffering from obstructive lung diseases such as bronchial asthma, bronchospasm, or Chronic Obstructive Pulmonary Disease since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Heart Block

This medicine is not recommended for use in patients with a heart block greater than the first degree since it may worsen the patient's condition. Replacement with a suitable alternative should be done under your doctor's supervision.

Diabetes

This medicine should be used with caution in patients suffering from diabetes due to the increased risk of very low blood sugar levels. Close monitoring of blood sugar levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Liver disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of serious adverse effects. Close monitoring of liver function, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Glaucoma

This medicine should be administered with caution in patients suffering from glaucoma. A change in the dose of the current glaucoma medicine may be required in some cases. Replacement with a suitable alternative may be necessary based on the clinical condition.

Hyperlipidemia

This medicine should be used with caution in patients suffering from hyperlipidemia due to the increased risk of worsening of the patient's condition. Close monitoring of cholesterol levels, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Cardiogenic shock

This medicine is not recommended for use in patients suffering from a cardiogenic shock since it may worsen the patient's condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as dizziness, headache, swelling of hands and feet, etc.
Coadministration of multivitamin with minerals and this combination medicine may decrease the effects of this medicine. Close monitoring of blood pressure and appropriate dose adjustments may be necessary in some cases based on the clinical condition. Your doctor may advise you to maintain an appropriate time gap between the consumption of multivitamin with minerals and this medicine to minimize their interaction.
Lab interactions
Information not available.
Take this medicine as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Amlodipine relaxes the heart muscles and the blood vessels. Metoprolol relaxes the blood vessels and reduces the heart rate, promoting a smooth flow of the blood. Their combination is thus effective in reducing the blood pressure and the strain on the heart.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Calcium channel blocking agents, Cardioselective beta blockers, Antihypertensive combinations

Schedule

Schedule H

DailyMed - Amlodipine tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 7 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=1cec7a02-b7a5-49e1-ab64-3a4dab4149d2

Amlodipine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 7 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a692044.html

[Internet]. 2017 [cited 7 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/24889

DailyMed - Metoprolol tartrate tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 9 November 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=011ee828-5c2a-49b9-bf8e-07f5eb5fc635
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