Metoz 5 mg Tablet

Manufactured byCentaur Pharmaceuticals Pvt. Ltd.
ContainsMetolazone
Description

Metoz 5 mg Tablet is a diuretic which is used to control blood pressure, edema (swelling), and fluid retention. It should be used with caution in patients with severe kidney disease. Frequent monitoring of blood pressure and electrolytes level is necessary while taking this medicine.

Side effects

Major & minor side effects for Metoz 5 mg Tablet

  • Chest pain
  • Dizziness
  • Dry mouth
  • Diarrhea
  • Joint pain, stiffness, and swelling
  • Cramping
  • Trembling
  • Increased urination
  • Itching or rash
  • Abdominal and stomach pain
  • Weakness

Uses of Metoz 5 mg Tablet

What is it prescribed for?

  • Hypertension
  • Edema
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is about 1 hour.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 12 to 24 hours.
  • Safe with alcohol?
    Consumption of alcohol is not recommended while you are taking this medicine. Their combination may increase the risk of dizziness, fainting, and a very low blood pressure. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine. Report any incidence of breathing difficulty or dizziness to the doctor immediately.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is recommended for use in pregnant women only when necessary. Discuss all the risks and benefits with your doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to metolazone.

Anuria

This medicine is not recommended for use in patients with a condition called anuria (a condition where the kidney is unable to produce urine).

Severe liver impairment

Metoz 5 mg Tablet is not recommended for use in patients with a known history of severe liver impairment due to the increased risk of hepatic coma and pre-coma. It is not recommended for use in patients with hepatic coma or pre-coma due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is recommended for use in pregnant women only when necessary. Discuss all the risks and benefits with your doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. Discuss all the risks and benefits with your doctor before taking this medicine.
General warnings

Hepatic dysfunction

Metoz 5 mg Tablet should be used with extreme caution in patient's suffering from liver diseases due to an increase in the risk of serious adverse effects including coma. Close monitoring of liver function is advised while taking this medicine. Report any symptoms of confusion or jaundice to the doctor on priority.

Volume and electrolyte depletion

Metoz 5 mg Tablet may alter the blood volume levels and electrolyte levels. This may cause dizziness, dry mouth, and acid-base imbalance. Close monitoring of blood pressure and electrolyte levels is necessary while taking this medicine. Report any symptoms such as weakness, lethargy, muscle pain, drowsiness, dizziness, irregular heartbeat, etc. to the doctor immediately.

Renal diseases

Metoz 5 mg Tablet may cause Azotemia in patients with a known history of a severe renal disease. Close monitoring of kidney function is necessary while taking this medicine. Appropriate dose adjustments should be done based on the renal function of the patient.

Missed Dose

If a dose of Metoz 5 mg Tablet is missed, take the dose as soon as you remember. If it is almost the time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while you are taking this medicine. Their combination may increase the risk of dizziness, fainting, and a very low blood pressure. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine. Report any incidence of breathing difficulty or dizziness to the doctor immediately.
Interaction with Medicine

Insulin

Antidepressants

Nonsteroidal anti-inflammatory medicines

Disease interactions

Diabetes

Metoz 5 mg Tablet may increase the blood glucose levels in patients with diabetes. Close monitoring of blood glucose levels is necessary for such patients. Suitable dose adjustments for the antidiabetic medicines or Metoz 5 mg Tablet may be required based on the clinical condition of the patient.

Hyperuricemia

Metoz 5 mg Tablet should be used with caution in patients with a history of gout or chronic renal failure due to the increased risk of hyperuricemia. Close monitoring of uric acid level is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Metoz 5 mg Tablet exactly as advised by your doctor. Do not take in larger amounts than prescribed. Take this medicine at daytime to prevent sleep disturbance. Drink an adequate amount of water. Monitoring of kidney function and electrolytes levels is necessary while taking this medicine. This medicine should be used with caution due to the risk of dizziness. Ensure that the course of treatment is completed. Report any adverse effects to the doctor on priority.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Metoz 5 mg Tablet works by increasing the excretion of water and sodium from the kidneys. This helps in bringing down the blood pressure as well as swelling.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Thiazide diuretics

Schedule

N/A

DailyMed - METOLAZONE- metolazone tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 3 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=0b619826-2567-49d7-8972-b6da5e4467df

Metolazone - DrugBank [Internet]. Drugbank.ca. 2017 [cited 3 August 2017]. Available from:

https://www.drugbank.ca/drugs/DB00524

Metolazone: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 3 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a682345.html

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 3 August 2017]. Available from:

http://www.tga.gov.au/prescribing-medicines-pregnancy-database
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Information on this page was last updated on 5 Oct 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.