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Metopar Tablet
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Metopar Tablet

Manufactured byADCOCK INGRAM HEALTHCARE PVT LTD
ContainsMetoclopramide (5 mg) + Paracetamol (500 mg)
Description
Metopar Tablet is a combination medicine which may be used for the symptomatic treatment of migraine headache. This medicine is not recommended for use in patients below 18 years of age.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Metopar Tablet

  • Allergic skin reaction
  • Gastric / Mouth Ulcer
  • Bloody and cloudy urine
  • Anemia
  • Fatigue
  • Dizziness
  • Abdominal pain
  • Convulsions (seizures)
  • Irregular heartbeat
  • Diarrhea
  • Restlessness
  • Breast pain and tenderness

Uses of Metopar Tablet

What is it prescribed for?

  • Migraine
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 30-60 minutes of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 4-6 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to metoclopramide, paracetamol, or any other inactive ingredients present in the formulation.

Analgesic Nephropathy (Kidney Disease)

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers due to the increased risk of worsening of the patient's condition.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver diseases due to the increased risk of worsening of the patient's condition.

Gastrointestinal disorders

This medicine is not recommended for use in patients with gastrointestinal disorders like gastrointestinal hemorrhage, mechanical obstruction, and gastrointestinal perforation due to the increased risk of worsening of the patient's condition.

Epilepsy

This medicine is not recommended for use in patients with epilepsy due to the increased risk of worsening of the patient's condition.

Pheochromocytoma

This medicine is not recommended for use in patients with conditions like pheochromocytoma due to an increase in the risk of hypertensive crisis (very severe increase in the blood pressure).
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Overdose

Read the label carefully before consuming this medicine to avoid overdosage. Overdose may result in liver damage. Seek emergency medical attention if an overdose of this medicine is suspected.

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Chronic Malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Neuroleptic Malignant Syndrome (NMS)

Use of this medicine may cause Neuroleptic Malignant Syndrome which is characterized by hyperthermia (fever), muscle rigidity, and altered consciousness. Report to the doctor immediately if these symptoms appear. Discontinue the treatment with this medicine if the symptoms persist.

Depression

Use of this medicine may cause depression in patients with or without the prior history of depression. Any symptoms of change in behavior or suicidal thoughts should be informed to the doctor on priority. Discontinue the treatment with this medicine if the symptoms worsen.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Driving or Operating machinery

Use of this medicine may cause drowsiness or dizziness in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Carbamazepine

Phenytoin

Sodium Nitrite

Leflunomide

Prilocaine

Atropine

Chlorpromazine

Disease interactions

Alcoholism

This medicine should be used with extreme caution in patients with chronic alcohol use due to the increased risk of serious liver injuries. Close monitoring of liver function is recommended for such patients. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any symptoms such as nausea, fever, rashes, dark urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Gastrointestinal Disorders

This medicine is not recommended for use in patients with gastrointestinal disorders like mechanical bowel obstruction, bowel perforation, or gastrointestinal hemorrhage due to the increased risk of worsening of the patient's condition. An alternative treatment option should be considered based on the clinical condition.

Parkinson's disease

This medicine should be used with caution in patients with Parkinson's disease due to an increase in the risk of parkinsonian-like symptoms such as akinesia, bradykinesia, tremors, pill-rolling motion, and postural abnormalities. These symptoms will usually appear within the first 6 months of the treatment and subside within 2 to 3 months after discontinuation of the treatment.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
Metoclopramide works by increasing the movement of food in the stomach and the intestine. It also blocks the action of a chemical in the brain responsible for nausea and vomiting. Paracetamol works by increasing the pain threshold and decreasing swelling. It also brings down elevated body temperature by acting on heat regulatory centers in the brain.
Legal Status

Unknown

Unknown

Unknown

Approved

Classification

Category

Miscellaneous analgesics, Miscellaneous antiemetics

Schedule

Schedule H

Paramax 500mg/5mg Tablets - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2019 [cited 2 July 2019]. Available from:

https://www.medicines.org.uk/emc/product/9244/smpc

Metoclopramide - DrugBank [Internet]. Drugbank.ca. 2017 [cited 20 June 2017]. Available from:

https://www.drugbank.ca/drugs/DB01233

Acetaminophen | C8H9NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 22 February 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/1983#section=Top

Metoclopramide: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 20 June 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a684035.html

Acetaminophen: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 22 September 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a681004.html
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Information on this page was last updated on 2 Jul 2019

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