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Metoclopramide (Agron) 5 mg Syrup

Manufactured by: Agron Remedies Pvt. Ltd.
Composition: Metoclopramide
Prescription Required: Yes
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Description

Metoclopramide (Agron) 5 mg Syrup is an antiemetic which is used to prevent nausea and vomiting caused by cancer chemotherapy and radiation therapy. It works by blocking the action of a chemical substance that causes nausea and vomiting. It is not recommended for use in patients with gastrointestinal disorders like gastrointestinal hemorrhage, mechanical obstruction, or gastrointestinal perforation.

Side effects

Major & minor side effects for Metoclopramide (Agron) 5 mg Syrup

  • Dizzinesssevererare
  • Abdominal painsevererare
  • Convulsionssevererare
  • Headachesevererare
  • Skin rashsevererare
  • Irregular heartbeatsevererare
  • Diarrhea
  • Restlessness
  • Breast pain and tenderness
  • Increased flow of breast milk
SEVERE
Contact your doctor immediately if any of these symptoms are experienced on a regular basis.
RARE
Observed in a small fraction of population.
This is not an exhaustive list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Highlights

Commonly asked questions for Metoclopramide (Agron) 5 mg Syrup

Onset of action

The effect of this medicine can be observed in 30 to 60 minutes after an oral dose, 1 to 3 minutes after an intravenous dose, and 10 to 15 minutes after an intramuscular dose.

Duration of effect

The effect of this medicine lasts for an average duration of 1 to 2 hours.

Safe with alcohol?

moderate
Alcohol should not be consumed while receiving this medicine as it may increase the risk of dizziness and lightheadedness. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and Metoclopramide (Agron) 5 mg Syrup are used together.

Is it habit forming?

No habit forming tendency has been reported.

Usage in pregnancy?

This medicine is recommended for use in pregnant women only if necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Usage while breast-feeding?

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Substitutes

List of substitutes for Metoclopramide (Agron) 5 mg Syrup

Below is the list of medicines, which have the same composition, strength and form as Metoclopramide (Agron) 5 mg Syrup, and hence can be used as its substitute.
Perinorm 5 mg Syrup
Ipca Laboratories Pvt. Ltd.

What is it prescribed for?

Uses of Metoclopramide (Agron) 5 mg Syrup

  • Chemotherapy induced nausea and vomiting

    Metoclopramide (Agron) 5 mg Syrup is used to treat nausea and vomiting associated with the use of chemotherapy medicines for the treatment of cancer.

  • Gastroparesis

    Metoclopramide (Agron) 5 mg Syrup is used in the treatment of Gastroparesis since it increases the gastric emptying and prevents nausea and vomiting.

  • Gastroesophageal Reflux Disease

    Metoclopramide (Agron) 5 mg Syrup is used in the treatment of Gastroesophageal Reflux Disease since it increases the gastric emptying and reduces the reflux of gastric contents.

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When not to use?

Contraindications of Metoclopramide (Agron) 5 mg Syrup

  • Allergy

    This medicine is not recommended for use in patients with a known allergy to Metoclopramide (Agron) 5 mg Syrup.

  • Gastrointestinal disorders

    This medicine is not recommended for use in patients with gastrointestinal disorders like gastrointestinal hemorrhage, mechanical obstruction, and gastrointestinal perforation.

  • Seizure disorder

    This medicine is not recommended for use in patients with a known history of seizures.

  • Pheochromocytoma

    This medicine is not recommended for use in patients with conditions like pheochromocytoma due to an increase in the risk of hypertensive crisis (very severe increase in the blood pressure).

Dosage

  • Missed Dose

    The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost the time for the next dose.

  • Overdose

    Seek emergency medical treatment or contact the doctor in case of an overdose.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcoholmoderate

  • Description

    - Consumption of alcohol with Metoclopramide (Agron) 5 mg Syrup will have an additive effect and can cause central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.

  • Instructions

    - Alcohol should not be consumed while receiving this medicine as it may increase the risk of dizziness and lightheadedness. Avoid performing activities that need high mental alertness like driving a vehicle or operating heavy machinery if alcohol and Metoclopramide (Agron) 5 mg Syrup are used together.

Interaction with Medicine

Disease interactions

  • Gastrointestinal Disorders

    severe
    Metoclopramide (Agron) 5 mg Syrup is not recommended for use in patients with gastrointestinal disorders like mechanical bowel obstruction, bowel perforation, or gastrointestinal hemorrhage. An alternative treatment option should be considered based on the clinical condition.

  • Parkinson's disease

    moderate
    Metoclopramide (Agron) 5 mg Syrup should be used with caution in patients with Parkinson's disease due to an increase in the risk of parkinsonian-like symptoms such as akinesia, bradykinesia, tremors, pill-rolling motion, and postural abnormalities. These symptoms will usually appear within the first 6 months of the treatment and subside within 2 to 3 months after discontinuation of the treatment.

Food interactions

  • Information not available.

Lab interactions

  • Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take Metoclopramide (Agron) 5 mg Syrup as advised by the doctor. Do not take this medicine if you have gastrointestinal disorders like mechanical bowel obstruction, bowel perforation, or gastrointestinal hemorrhage. Monitoring of blood pressure and symptoms like involuntary movements of the tongue, lips, face, and trunk is necessary while consuming this medicine.

Warnings

Warnings for special population

  • Pregnancy

    - This medicine is recommended for use in pregnant women only if necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

  • Breast-feeding

    - This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

General warnings

  • Neuroleptic Malignant Syndrome (NMS)

    - Metoclopramide (Agron) 5 mg Syrup is known to cause Neuroleptic Malignant Syndrome which is characterized by hyperthermia (fever), muscle rigidity, and altered consciousness. Report to the doctor immediately if these symptoms appear. Discontinue Metoclopramide (Agron) 5 mg Syrup treatment if the symptoms persist.

  • Depression

    - Metoclopramide (Agron) 5 mg Syrup may cause depression in patients with or without the prior history of depression. Any symptoms of change in behavior or suicidal thoughts should be informed to the doctor on priority. Discontinue the treatment if the symptoms worsen.

Other details

  • To be taken before food
  • To be taken as instructed by doctor
  • May cause sleepiness

How it works

It works by increasing the movement of food in the stomach and the intestine.

Legal Status

Approved
Approved
Approved
Approved

Classification

Category
GI stimulants
Schedule
Schedule H

References

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Information on this page was last updated on 5 Jan 2018

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Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.