Methyl Prednisolone

Description

Methyl Prednisolone is a corticosteroid which is used to relieve symptoms such as pain and swelling in various conditions like arthritis and allergic disorders. Do not stop the use of this medicine suddenly since this may cause severe side effects.

Side effects

Major & minor side effects for Methyl Prednisolone

  • Aggression or anger
  • Decreased urine output
  • Dizziness
  • Headache
  • Difficulty in breathing
  • Change in mood
  • Increased appetite

Uses of Methyl Prednisolone

What is it prescribed for?

  • Acute Gout
  • Psoriasis
  • Nephrotic syndrome
  • Rheumatoid Arthritis
  • Asthma
  • Osteoarthritis
  • Bursitis
  • Lichen simplex chronicus
  • Lichen Planus
  • Keloids
  • Granuloma annulare
  • Multiple sclerosis
  • Allergic rhinitis
  • Tendonitis
  • Synovitis
  • Dermatitis
  • Eczema
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 1 to 2 hours after oral administration and 6 to 48 hours after intramuscular administration. The onset of action is rapid after intravenous administration. The time required for the topical form of this medicine to show its action is not clinically established.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 30-36 hours after an oral dose and 1-4 weeks after an intramuscular injection. The time for which this medicine remains active in the body is not clinically established for the intravenous and topical forms of this medicine.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to methyl prednisolone, any other glucocorticoids, or any other inactive ingredients present along with it.

Fungal infections

This medicine is not recommended for use in patients suffering from systemic fungal infections due to the increased risk of worsening of the patient's condition.

Idiopathic thrombocytopenic purpura

Intramuscular injection of this medicine is not recommended for use in patients with a known history of Idiopathic thrombocytopenic purpura due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Infections

This medicine should be used with caution in patients who are at risk of developing infections. The severity of the infections may increase with an increase in the dose of this medicine. This medicine is not recommended for use in patients who are suffering from systemic fungal infections since it may worsen the patient's condition.

Vaccination

This medicine may decrease the effect of live or attenuated vaccines. Your doctor may suggest an appropriate time gap between the administration of the medicine and the vaccine to avoid their interaction. Alternatively, therapy with the medicine or the vaccine may be postponed depending on your clinical condition.

Diabetes

This medicine may alter the blood glucose levels and worsen the symptoms of diabetes. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Gastrointestinal diseases

This medicine should be used with caution in patients with gastrointestinal diseases due to the increased risk of gastrointestinal bleeding. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Impaired kidney function

This medicine should be used with caution in the patients with a known history of kidney injury since it may worsen the patient's condition. Close monitoring of kidney function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Impaired liver function

This medicine should be used with caution in patients with a known history of liver injuries due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Missed Dose

Oral/Topical forms: Apply/Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one. Injections: If you miss a scheduled dose of the injection, contact your doctor for further instructions.

Overdose

Oral/Topical forms: Seek emergency medical treatment or contact the doctor in case of an overdose. Injections: Since this medicine is usually administered under the supervision of a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be provided if your doctor suspects an overdose of this medicine.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Ethinyl Estradiol

Azole antifungal agents

Antihypertensives

Nonsteroidal anti-inflammatory drugs

Disease interactions

Gastro-intestinal bleeding

This medicine should be used with caution in patients with a known history of gastrointestinal diseases due to the increased risk of bleeding. This risk is especially higher when the medicine is taken for a long duration of time. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Diabetes

This medicine should be used with caution in patients with a known history of diabetes due to the increased risk of altered blood glucose levels. Regular monitoring of blood glucose levels, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of severe adverse effects.
Lab interactions
Information not available.
Use this medicine exactly as advised by your doctor. Do not use in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
It works by binding to the receptors and inhibiting the release of certain chemical substances that cause pain and swelling.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Glucocorticoids

Schedule

Schedule H

DailyMed - Methylprednisolone tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 15 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7bf4d3d3-3f8a-4e20-9194-061658efca61

[Internet]. 2017 [cited 15 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/1536

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 15 March 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname

[Internet]. Toxnet.nlm.nih.gov. 2017 [cited 15 March 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~J0sBCv:1

[Internet]. Medsafe.govt.nz. 2018 [cited 1 February 2018]. Available from:

http://www.medsafe.govt.nz/profs/Datasheet/a/Advantanointcrm.pdf

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 2 Feb 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.