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Mesacol Enema

Manufactured bySun Pharma Laboratories Ltd.
Description
Mesacol Enema is used for the treatment of ulcerative proctitis (a mild form of ulcerative colitis, involving only the rectum), and proctosigmoiditis (a mild form of ulcerative colitis, involving the rectum and sigmoid colon) characterized by rectal bleeding, bloody diarrhea, redness, and ulcerations of the lining of the rectum.

Side effects

Major & minor side effects for Mesacol Enema

  • Rectal pain
  • Rectal Irritation
  • Dizziness
  • Skin rash
  • Flatulence (Passing of gas)

Uses of Mesacol Enema

What is it prescribed for?

  • Ulcerative proctitis and proctosigmoiditis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required by this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to mesalazine or any other components present along with the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
General warnings

Use of nephrotoxic medicines

The use of nephrotoxic medicines along with this medicine may increase the risk of kidney damage. Close monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition. It is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine to avoid such interactions.

Use of nonsteroidal anti-inflammatory drug (NSAIDs)

The use of NSAIDs along with this medicine may increase the risk of kidney impairment. Replacement with a suitable alternative should be considered under your doctor's supervision. It is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine to avoid such interactions.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Use in children

This medicine is not recommended for use in children under 18 years of age since safety and efficacy are not clinically established.

Missed Dose

Use the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Kidney impairment

This medicine should be used with caution in patients with a history of kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Use this medicine as advised by your doctor. Do not use in larger amounts than advised. Consult the doctor if you experience any undesirable side effects. Follow all the instructions given in the patient information leaflet.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine reduces and prevents the worsening of symptoms of ulcerative proctitis and proctosigmoiditis by blocking the production of certain natural substances in the colon and rectum.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Anti-inflammatory agents, Rectal preparations

Schedule

Schedule H

Mesalamine Rectal: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2020 [cited 11 June 2020]. Available from:

https://medlineplus.gov/druginfo/meds/a614021.html

Internet]. Medsafe.govt.nz. 2020 [cited 11 June 2020]. Available from:

https://www.medsafe.govt.nz/Consumers/cmi/p/pentasa-enema.pdf

[Internet]. Rad-ar.or.jp. 2020 [cited 3 July 2020]. Available from:

https://www.rad-ar.or.jp/siori/english/kekka.cgi?n=1361
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Information on this page was last updated on 3 Jul 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.