Meropenem

Description

Meropenem is a broad spectrum antibiotic used to treat a variety of conditions caused by bacteria such as infections of stomach, brain, and lungs. It should be used with caution in patients with central nervous system disorders.

Side effects

Major & minor side effects for Meropenem

  • Swelling and redness at the injection site
  • Fever
  • Confusion
  • Fast heartbeat
  • Skin rash
  • Black or tarry stools
  • Decreased urine output
  • Diarrhea
  • Constipation
  • Body pain
  • Acid or sour stomach
  • White patches in the mouth or on the tongue

Uses of Meropenem

What is it prescribed for?

  • Bacterial Meningitis
  • Skin and structure Infection
  • Intra-abdominal Infection
  • Pneumonia
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine can be observed within 1 hour after intravenous infusion.
  • Duration of effect
    The effect of this medicine lasts for an average of 3 to 4 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    Limited data is available on the use of this medicine in pregnant women. Use only if clearly needed under the supervision of the doctor.
  • Usage while breast-feeding?
    This medicine can be used by breastfeeding women. Small amount of this medicine is excreted in human breast milk. Monitoring of undesired effects like diarrhea or thrush is necessary.

Allergy

Avoid if you have a known allergy to Meropenem or any other carbapenem antibiotics and beta-lactam antibiotics.
Warnings for special population

Pregnancy

Limited data is available on the use of this medicine in pregnant women. Use only if clearly needed under the supervision of the doctor.

Breast-feeding

This medicine can be used by breastfeeding women. Small amount of this medicine is excreted in human breast milk. Monitoring of undesired effects like diarrhea or thrush is necessary.
General warnings

Allergy

Avoid if you have a known allergy to Meropenem or any Carbapenem and Beta-lactam Antibiotics like penicillins and cephalosporins. Seek immediate medical attention if the patient experiences any allergic symptoms like rash, itching, nausea or vomiting, swelling of lips, hands, and feet.

Drug-resistance

Usage of Meropenem without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that is drug resistant.

Clostridium difficile-associated Diarrhea

Avoid if you experience severe diarrhea after receiving Meropenem. As antibiotic therapy will cause an imbalance in the normal microbial flora in the large intestine which promotes the growth of bacteria called Clostridium difficile.

Seizures

Meropenem may cause seizures and other central nervous system disturbances. Use with caution in the patients with a history of seizures or any brain infections.

Pediatric use

The safety and efficacy of Meropenem is not established in children less than 3 months of age.

Impaired kidney function

Use with caution the patients with the kidney injury. Dose adjustments are to be made if CrCl is less than 50 ml/min.

Missed Dose

The missed dose should be taken as soon possible. It is advisable to skip the missed dose if it's already time for your next scheduled dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Tramadol

Ethinyl Estradiol

Cholera Vaccine

Valproic Acid

Disease interactions

Central nervous system disorders

Meropenem may cause seizures, confusion, and agitation. Use with caution the patients with seizures or any central nervous system disorders.

Colitis

Avoid if you experience severe diarrhea, abdominal pain, and blood in stools after taking Meropenem. Inform the doctor if you have any gastrointestinal diseases. Drink adequate amount of water to prevent dehydration.
Food interactions
Information not available.
Lab interactions
Information not available.
Make sure that the medicine is dissolved properly. Do not take if any particulate matter is visible. Consult the doctor if you experience any undesirable effects. Do not stop taking before completion of course.
Miscelleneous

Food timings: Information not available

Administration time: Information not available

Sleep inducing: Information not available

How it works
Meropenem is a broad spectrum antibiotic. It works by interfering with the bacterial cell wall synthesis.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Carbapenems

Schedule

SCHEDULE H

Meropenem: Indications, Side Effects, Warnings - Drugs.com [Internet]. Drugs.com. 2017 [cited 14 March 2017]. Available from:

https://www.drugs.com/cdi/meropenem.html

[Internet]. 2017 [cited 14 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/11215

DailyMed - MEROPENEM - meropenem injection [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 14 March 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=4e4e2c0c-df54-4229-ab90-fa671ecedd57

Merrem IV (meropenem) dosing, indications, interactions, adverse effects, and more [Internet]. Reference.medscape.com. 2017 [cited 14 March 2017]. Available from:

http://reference.medscape.com/drug/merrem-iv-meropenem-342565

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 14 March 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname

TOXNET [Internet]. Toxnet.nlm.nih.gov. 2017 [cited 14 March 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2/f?./temp/~CjIYgk:1

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Information on this page was last updated on 20 Mar 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.