Mephentermine

Description

Mephentermine is used for the maintenance of blood pressure levels in patients with low blood pressure states (hypotensive states). It is also used to correct blood pressure levels if the blood pressure levels drop following spinal anesthesia in pregnant patients.

Side effects

Major & minor side effects for Mephentermine

  • High blood pressure
  • Skin Rash
  • Difficulty in breathing
  • Weakness
  • Drowsiness
  • Sleeplessness
  • Nausea
  • Vomiting

Uses of Mephentermine

What is it prescribed for?

  • Hypotension
  • Hypotension secondary to spinal anaesthesia in obstetric patients
Read More
Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 5 to 15 minutes of an intramuscular administration. In the case of an intravenous administration, the effect of this medicine can be observed immediately.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 4 hours on an intramuscular administration and 30 minutes on an intravenous administration.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies have been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the appropriate course of treatment after evaluating all the risks and benefits associated with the use of this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Hypotension

This medicine is not recommended for use in patients suffering from hypotension caused by phenothiazines (chlorpromazine, triflupromazine, perphenazine, etc.) due to the increased risk of worsening of the patient's condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to mephentermine or any other inactive components present along with it.

Pheochromocytoma

This medicine is not recommended for use in patients suffering from pheochromocytoma (a tumor in the adrenal gland) due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the appropriate course of treatment after evaluating all the risks and benefits associated with the use of this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Hyperthyroidism

This medicine should be used with extreme caution in patients suffering from hyperthyroidism due to the increased risk of worsening of the patient's condition. Your doctor may perform thyroid function tests prior to and post administration of this medicine to check your thyroid hormone levels. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Cardiovascular diseases

This medicine should be used with extreme caution in patients with cardiovascular diseases due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or operating machinery

This medicine is usually administered to correct blood pressure levels in low blood pressure states following spinal anesthesia. If this medicine is administered for any other circumstances that cause low blood pressure, your doctor may advise you not to perform any activities that require high mental alertness like driving a vehicle or operating machinery.

Use in Children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established. However, your doctor may prescribe this medicine if the benefits significantly outweigh the risks. In such a case, close monitoring of the clinical condition is advised.

Missed Dose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

MAO inhibitors

Oxytocin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine should be administered by a qualified healthcare professional. Inform the doctor if you have a known history of allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
It increases the blood flow by increasing the heart rate and cardiac output, thus correcting low blood pressure levels.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Vasopressors, Vasoconstrictor, Cardiac Stimulant

Schedule

Schedule H

Mephentermine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 1 October 2018]. Available from:

https://www.drugbank.ca/drugs/DB01365

Mephentermine [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 1 October 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/mephentermine

Mephentermine- National Library of Medicine HSDB Database [Internet]. Toxnet.nlm.nih.gov. 2019 [cited 9 January 2019]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search/a?dbs+hsdb:@term+@DOCNO+2172

How will this medicine affect me?

Consult top doctors online and get an answer now
Chat now
Chat now

Looking for a doctor?

Book an appointment with the top doctors near you
Book now
Book now
Something doesn’t feel right?
Report an error

Information on this page was last updated on 10 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.