Melitracen

Description

Melitracen is a tricyclic antidepressant used for the treatment of depression. You are advised to avoid an abrupt discontinuation of therapy with this medicine since this may cause withdrawal symptoms. Do not stop the use of this medicine without consulting your doctor.

Side effects

Major & minor side effects for Melitracen

  • Drowsiness
  • Weight gain
  • Hallucinations
  • Tremors
  • Itching of skin
  • Migraine like headaches

Uses of Melitracen

What is it prescribed for?

  • Depression
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended while receiving this medicine since it may increase the risk of severe adverse effects such as extreme drowsiness, confusion, vomiting, blurred vision, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    The habit-forming potential of this medicine is not clinically established. However, since many antidepressants have a habit-forming potential, this medicine may show a habit-forming tendency in some patients.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to melitracen or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. If the medicine is used, the infant should be monitored closely for any undesirable side effects.
General warnings

Kidney Diseases

This medicine should be used with extreme caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Regular monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Liver Diseases

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Regular monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Other Medicines

Melitracen may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Driving or Operating machinery

Use of this medicine may cause symptoms such as dizziness, drowsiness, restlessness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Drug Withdrawal

Abrupt discontinuation of this medicine may increase the risk of severe adverse effects; this risk is especially higher if you have been using a high dose of this medicine for a prolonged period of time. A gradual dose reduction is recommended to avoid these adverse effects (withdrawal symptoms). Do not stop the use of this medicine without consulting your doctor.

Suicidal tendencies

This medicine should be used with caution due to the increased risk of suicidal tendencies. Patients should be monitored closely for any change in mood or behavior. Appropriate patient/caregiver counseling, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while receiving this medicine since it may increase the risk of severe adverse effects such as extreme drowsiness, confusion, vomiting, blurred vision, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Monoamine oxidase inhibitors

CNS depressants

Disease interactions

Cardiovascular disorders

This medicine should be used with caution in patients with a history of cardiovascular diseases due to the increased risk of severe side effects. These side effects may include an increased heart rate, irregular heart rhythm, etc. Close monitoring of heart function and vital signs is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Diabetes

This medicine should be used with caution in patients suffering from diabetes due to the increased risk of fluctuations in blood sugar levels. Close monitoring of blood glucose levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as instructed by the doctor. Do not take in larger or smaller amounts than prescribed. Seek emergency medical treatment in case of any severe adverse effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor since abrupt discontinuation may cause severe withdrawal symptoms.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine increases the levels of certain chemical substances in the brain (norepinephrine and serotonin) to improve the symptoms of depression.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Tricyclic antidepressants

Schedule

Schedule H

Melitracen [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 3 August 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Melitracen

Melitracen - DrugBank [Internet]. Drugbank.ca. 2018 [cited 3 August 2018]. Available from:

https://www.drugbank.ca/drugs/DB13384

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Information on this page was last updated on 17 Aug 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.