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Megapen Drops
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Megapen Drops

Manufactured byARISTO PHARMACEUTICALS PVT LTD
ContainsAmpicillin (100 mg) + Cloxacillin (50 mg)
Description
Megapen Drops is a combination medicine which may be used for the treatment of respiratory tract infections, osteomyelitis, septicemia, post-operative wound infections, etc caused by the susceptible bacteria. This medicine is not recommended for treating common cold, flu or other viral infections since it is not effective in treating them.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Megapen Drops

  • Nausea or Vomiting
  • Diarrhea
  • Skin Rash
  • Abdominal pain
  • Dizziness
  • Yellowing of skin and eyes

Uses of Megapen Drops

What is it prescribed for?

  • Osteomyelitis (Infection of bone)
  • Respiratory Tract Infection
  • Post operative infections
  • Bacterial Septicemia
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 30 minutes after the administration.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 3 to 6 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women.

Allergy

This medicine is not recommended for use in patients with a known allergy to ampicillin, cloxacillin, other antibiotics of the penicillin or cephalosporin group, or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women.

Breast-feeding

This medicine is not recommended for use in breastfeeding women.
General warnings

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing the benefits and even cause toxicity. It may also increase the risk of development of bacteria that are drug-resistant.

Clostridium difficile-associated diarrhea

Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in such cases.

Hypersensitivity reactions

This medicine may cause serious and occasionally fatal hypersensitivity reactions including anaphylactic shock in some patients. This risk is especially high in patients with a history of sensitivity to multiple allergens. If an anaphylactic reaction occurs, the treatment should be discontinued immediately and appropriate corrective measures should be undertaken.

Missed Dose

Administer the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Live cholera vaccine

Chloramphenicol

Methotrexate

Tetracycline

Warfarin

Disease interactions

Kidney Disease

This medicine should be used with extreme caution in patients with kidney diseases due to the increased risk of adverse effects. Regular monitoring of kidney function, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Bone Marrow Depression

This medicine should be used with caution in patients with bone marrow depression due to the increased risk of worsening of the patient's condition. Close monitoring of blood counts is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Colitis

This medicine should be used with extreme caution in patients having a history of gastrointestinal diseases, particularly colitis, since it may worsen the patient's condition. Report any incidence of severe diarrhea, abdominal pain, blood in stools, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
The absorption of this medicine may decrease in the presence of food. For proper absorption of the medicine, it should be administered at least 30 minutes or 1 hour before feeding.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Administer this medicine as instructed by your doctor. Do not take/administer in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable effects. Do not stop taking the medicine before completion of the course/without consulting your doctor.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by interfering with certain processes that help the bacteria to form new cell walls. This helps in stopping the growth and multiplication of bacteria and eventually kills them.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Aminopenicillins, Penicillinase resistant penicillins

Schedule

Schedule H

Cloxacillin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 16 March 2018]. Available from:

https://www.drugbank.ca/drugs/DB01147

Ampicillin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 30 August 2018]. Available from:

https://www.drugbank.ca/drugs/DB00415

[Internet]. Gskpro.com. 2019 [cited 10 December 2019]. Available from:

https://gskpro.com/content/dam/global/hcpportal/en_NG/PDF/Home/Products/Ampiclox_GA_03.pdf
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Information on this page was last updated on 6 Jan 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.