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Meftagesic Tablet

Manufactured byBlue Cross Laboratories Ltd.
ContainsMefenamic acid (500 mg) + Paracetamol (325 mg)
Description

Meftagesic Tablet is a combination medicine which may be used for the treatment of acute musculoskeletal disorders such as sprains, strains, injuries, etc. It may also be used for the treatment of a headache, dental pain, low back pain, osteoarthritis, rheumatoid arthritis, etc. It should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects.

Side effects

Major & minor side effects for Meftagesic Tablet

  • Nausea or Vomiting
  • Allergic skin reaction
  • Gastric / Mouth Ulcer
  • Anemia
  • Diarrhea
  • Constipation
  • Headache
  • Ringing or buzzing in the ears
  • Blurred vision
  • Weight gain
  • Shortness of breath
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Fast heartbeat
  • Yellow colored eyes or skin
  • Difficult or painful urination
  • Excessive tiredness

Uses of Meftagesic Tablet

What is it prescribed for?

  • Acute Pain
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 20-30 minutes of administration.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 4-6 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, jaundice, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Analgesic Nephropathy (Kidney Disease)

This medicine is not recommended for use in patients suffering from kidney diseases associated with the excessive use of painkillers due to the increased risk of worsening of the patient's condition.

Severe liver impairment

This medicine is not recommended for use in patients with severe liver diseases due to the increased risk of worsening of the patient's condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to mefenamic acid, other NSAIDs, paracetamol, or any other inactive ingredients present along with these medicines.

Coronary Artery Bypass Surgery (CABG)

This medicine is not recommended for use in patients who have undergone a coronary artery bypass graft surgery recently due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Chronic Malnutrition

This medicine should be used with extreme caution in patients suffering from malnourishment due to the increased risk of severe adverse effects. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Effect on heart

Use of this medicine for a long duration may cause fluid retention and heart failure. Hence, it should be administered with caution in patients suffering from a disease of the heart or blood vessels. Close monitoring of heart function and vital signs, dose adjustments, or replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.

Peptic ulcer

This medicine should be used with caution in patients suffering from peptic ulcer or other diseases of the gastrointestinal tract since it may worsen the patient's condition. An alternative treatment option may be necessary in some cases based on the clinical condition of the patient.

Allergic skin reactions

Use of this medicine can cause a series of allergic skin reactions (Stevens-Johnson syndrome or toxic epidermal necrolysis) in some patients. Therapy should be stopped immediately if signs of a skin allergy are observed.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, rashes, nausea, joint pain, fever, jaundice, etc.
Interaction with Medicine

Carbamazepine

Glimepiride

Methotrexate

Phenytoin

Propranolol

Ramipril

Tacrolimus

Warfarin

Sodium Nitrite

Leflunomide

Prilocaine

Aspirin

Spironolactone

Disease interactions

Impaired kidney function

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Liver Disease

This medicine should be used with extreme caution in patients with liver function impairment or active liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is necessary while receiving this medicine. Report any symptoms such as nausea, fever, rashes, dark urine, etc. to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Asthma

This medicine is not recommended for use in patients suffering from aspirin-sensitive asthma due to the increased risk of worsening of the patient's condition. It should be used with caution in patients suffering from other types of asthma or other broncho-obstructive disorders since it may worsen the patient's condition. Replacement with a suitable alternative may be necessary in some cases based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions

5-HIAA Urine Test

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.

Diazo test for urinary bile

Report the use of this medicine before undergoing the diazo test for determination of urinary bile content. This medicine can potentially yield a false positive result for this test.
Take this medicine exactly advised by your doctor. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by stopping the production of certain chemicals in the body that causes swelling, pain, and fever. It also brings down the body temperature by acting on heat regulatory centers in the brain.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Nonsteroidal anti-inflammatory agents, Miscellaneous analgesics

Schedule

Schedule H

Acetaminophen | C8H9NO2 - PubChem [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 22 August 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/1983#section=Top

Mefenamic acid [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 22 August 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/4044

Acetaminophen - DrugBank [Internet]. Drugbank.ca. 2018 [cited 22 August 2018]. Available from:

https://www.drugbank.ca/drugs/DB00316

Mefenamic acid - DrugBank [Internet]. Drugbank.ca. 2018 [cited 22 August 2018]. Available from:

https://www.drugbank.ca/drugs/DB00784
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Information on this page was last updated on 20 Dec 2018

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