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Mefariv-T Tablet

Manufactured byEAST AFRICAN REMEDIES (INDIA) PVT LTD
ContainsMefenamic acid (250 mg) + Tranexamic Acid (250 mg)
Description

Mefariv-T Tablet is a combination medicine which may be used in the treatment of heavy menstrual bleeding and acute pain that occurs with menstrual disorders. This medicine is not recommended for use in children.

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Side effects

Major & minor side effects for Mefariv-T Tablet

  • Bloating
  • Headache
  • Diarrhea
  • Dizziness
  • Ringing or buzzing in the ears
  • Blurred vision
  • Weight gain
  • Shortness of breath
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Peeling and blistering of skin
  • Fast heartbeat
  • Unusual bleeding or bruising
  • Yellow colored eyes or skin
  • Difficult or painful urination
  • Bloody and Cloudy urine
  • Excessive tiredness
  • Back pain
  • Anemia

Uses of Mefariv-T Tablet

What is it prescribed for?

  • Primary Dysmenorrhea (Painful menstruation cycle)
  • Menorrhagia (excessive menstrual bleeding)
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within 20-30 minutes of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 6 hours.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, drowsiness, confusion, difficulty in concentrating, a very low blood pressure, severe gastrointestinal bleeding, etc.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to mefenamic acid, tranexamic acid, or any other ingredients present along with this formulation.

Other allergic conditions

This medicine is not recommended for use in patients with allergic conditions such as asthma or urticaria since it may worsen the patient's condition.

Coronary Artery Bypass Surgery (CABG)

This medicine is not recommended for use before or after a CABG (coronary artery bypass graft) procedure since it may worsen the patient's condition.

Acquired defective color vision

This medicine is not recommended for use in patients with a defective color vision since this condition hinders one endpoint of toxicity determination for the medicine.

Subarachnoid hemorrhage

This medicine is not recommended for use in patients with a subarachnoid hemorrhage due to the increased risk of worsening of the patient's condition.

Obstructive blood clotting disorder

This medicine is not recommended for use in patients having clotting disorders or patients predisposed to clotting disorders since it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on the clinical condition.
General warnings

Cardiovascular effects

Use of this medicine for a long duration may cause fluid retention and heart failure. This risk is especially higher in patients with a history of cardiovascular diseases. Appropriate corrective measures, frequent clinical monitoring, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Peptic ulcer

This medicine should be used with extreme caution in patients suffering from peptic ulcer disease due to the increased risk of severe gastrointestinal bleeding. Report any unusual bleeding or bruising to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Allergic skin reaction

This medicine may cause fatal skin allergies without any warnings which may require immediate medical attention. Signs and symptoms like rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures or replacement with a suitable alternative may be required based on the clinical condition.

Use of hormonal contraceptives

This medicine is not recommended for use in women who are using hormonal contraceptives (pills, patches, vaginal rings, or injections) due to the increased risk of serious adverse effects.

Ophthalmic disorders

This medicine is not recommended for use in patients with a history of any disease where the blood vessels of the eye are obstructed due to clot formation since it may worsen the patient's condition.

Clotting disorders

This medicine is not recommended for use in patients having clotting disorders or patients predisposed to clotting disorders since it may worsen the patient's condition.

Use in children

This medicine is not recommended for use in patients less than 18 years of age since the safety and efficacy of use are not clinically established. However, your doctor may prescribe this medicine if the benefits significantly outweigh the risks. In such a case, the patient should be monitored closely for any undesirable side effects.

Driving or Operating Machinery

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, drowsiness, confusion, difficulty in concentrating, a very low blood pressure, severe gastrointestinal bleeding, etc.
Interaction with Medicine

Propranolol

Furosemide

Glimepiride

Ramipril

Tretinoin

Methotrexate

Tacrolimus

Ethinyl Estradiol

Tamoxifen

Ketorolac

Warfarin

Spironolactone

Aspirin

Disease interactions

Asthma

This medicine is not recommended for use in patients with a known history of aspirin or NSAID-sensitive asthma. Replacement with a suitable alternative should be done under your doctor's supervision.

Impaired kidney function

This medicine should be used with extreme caution in patients with a history of kidney diseases or active kidney diseases. Appropriate dose adjustments, close monitoring of renal function, or replacement with a suitable alternative may be necessary based on the clinical condition.

Impaired liver function

This medicine should be used with caution in patients with a history of liver diseases or active liver diseases. Appropriate dose adjustments, close monitoring of liver function, or replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Information not available.
Lab interactions

Diazo test for urinary bile

You may get a false-positive result for this test while taking this medicine. It is advised that you inform the doctor and lab technician about all your current medicines including herbs and supplements before undergoing any lab tests.
Take this medicine as instructed by the doctor. Do not take in larger or smaller quantities than recommended. The dosage and the duration of use of this medicine should be kept as low as possible. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Mefenamic acid provides pain relief by blocking the production of certain chemicals responsible for causing pain and swelling. Tranexamic acid stabilizes the blood clot by inhibiting certain enzymes which break down the clot during a bleeding episode.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Analgesic combinations, Miscellaneous coagulation modifiers

Schedule

Schedule H

[Internet]. Medlineplus.gov. 2017 [cited 11 April 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a612021.html

[Internet]. Medlineplus.gov. 2017 [cited 30 May 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a681028.html

[Internet]. Drugbank.ca. 2017 [cited 30 May 2017]. Available from:

https://www.drugbank.ca/drugs/DB00784

[Internet]. Pubchem.ncbi.nlm.nih.gov. 2017 [cited 11 April 2017]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/5526#section=Top
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Information on this page was last updated on 30 Oct 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.