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Mefa Tablet

Manufactured byFRANKLIN LABORATORIES (INDIA) PVT LTD
ContainsDicyclomine (10 mg) + Mefenamic acid (250 mg)
Description
Mefa Tablet is used to relieve muscle cramps during periods. It also provides relief from pain due to muscle spasms in the stomach and intestines. Mefa Tablet is effective in relieving a sharp, localized pain called colicky pain in the intestines, gall bladder, and urinary tract (such as in the kidneys or ureter). Common side effects of Mefa Tablet are dizziness, sleepiness, stomach upset, dry mouth, blurred vision, nausea and vomiting. Inform your doctor if you are allergic to this medicine. Maintain caution while using Mefa Tablet in individuals with kidney and liver problems. Take Mefa Tablet with food to avoid stomach irritation. For the ease of remembering, take it at around the same time every day. Do not stop using this medicine until the doctor tells you.

Side effects

Major & minor side effects for Mefa Tablet

  • Diarrhoea
  • Stomach upset
  • Bloating
  • Headache
  • Dizziness and Drowsiness
  • Ringing or buzzing in the ears
  • Blurred vision
  • Weight gain
  • Shortness of breath
  • Swelling of face, lips, eyelids, tongue, hands and feet
  • Fast heartbeat
  • Unusual bleeding or bruising
  • Yellow coloured eyes or skin
  • Difficult or painful urination
  • Bloody and Cloudy urine
  • Nausea and vomiting
  • Dry mouth
  • Nervousness
  • Skin rash

Uses of Mefa Tablet

What is it prescribed for?

  • Spasmodic dysmenorrhoea
  • Colicky pains
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Mefa Tablet provides relief from pain within 30 to 60 minutes of administration.
  • How long do the effects of this medicine last?
    The duration of action for Mefa Tablet is 6 to 8 hours. You may have to take your next dose if your pain continues.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended while treatment with Mefa Tablet due to the risk of stomach bleeding.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Mefa Tablet.
  • Can this medicine be taken during pregnancy?
    Mefa Tablet is not recommended for use during pregnancy due to the risk of harmful effects on your baby. But in some cases, your doctor may prescribe this medicine if the benefits outweigh the risks. All the risks and benefits should be discussed with your doctor before using the medicine.
  • Can this medicine be taken while breast-feeding?
    Mefa Tablet is not recommended for use in breastfeeding women. An alternate medicine may be preferred, especially while nursing a newborn or preterm infant. If required, it should only be used upon your doctor's recommendation.

Allergy

Avoid taking Mefa Tablet if you are previously allergic to it. Seek immediate medical attention if you notice any symptoms of serious allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Gastrointestinal bleeding

Mefa Tablet may cause stomach and intestinal bleeding and ulcers. Therefore it is not recommended for use in patients with gastrointestinal bleeding or perforation disorders since it may worsen the condition.

Coronary Artery Bypass Surgery (CABG)

Do not use Mefa Tablet for relieving pain after heart surgery.

Asthma

Patients with asthma may experience allergic reactions while taking Mefa Tablet. Hence it is not recommended for use in patients with asthma, especially those who had experienced allergic reactions with the use of non-steroidal anti-inflammatory medicines.
Warnings for special population

Pregnancy

Mefa Tablet is not recommended for use during pregnancy due to the risk of harmful effects on your baby. But in some cases, your doctor may prescribe this medicine if the benefits outweigh the risks. All the risks and benefits should be discussed with your doctor before using the medicine.

Breast-feeding

Mefa Tablet is not recommended for use in breastfeeding women. An alternate medicine may be preferred, especially while nursing a newborn or preterm infant. If required, it should only be used upon your doctor's recommendation.
General warnings

Heart surgery

Do not use Mefa Tablet for relieving pain after heart surgery.

Allergic skin reaction

Mefa Tablet may cause serious skin allergies without any warnings. These events may be fatal in rare cases. Signs and symptoms like rashes, hives, fever, or other allergic symptoms should be reported to the doctor immediately. The treatment should be discontinued if these symptoms appear.

Driving or operating machinery

Mefa Tablet may cause sleepiness, blurred vision or dizziness in some patients. Hence it is advised not to drive vehicles and operate heavy machinery after taking this medicine.

Use in children

Use of Mefa Tablet is not recommended in children unless directed by a doctor.

Missed Dose

Take the missed dose of Mefa Tablet as soon as possible. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek medical emergency in case of Mefa Tablet overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while treatment with Mefa Tablet due to the risk of stomach bleeding.
Interaction with Medicine

Methotrexate

Ramipril

Tacrolimus

Warfarin

Furosemide

Aspirin

Ipratropium

Metformin

Disease interactions

Fluid retention

Mefa Tablet may cause fluid retention and hence should be used with extreme caution in patients with preexisting fluid retention. Blood pressure and heart function should be monitored closely during treatment with this medicine.

Kidney Disease

Prolonged use of high doses of Mefa Tablet may cause kidney problems, such as painful urination and protein or blood in the urine. Hence this medicine should be used cautiously in kidney impaired patients. Close monitoring of kidney function is necessary while receiving this medicine.

Liver Disease

Patients with liver diseases should ask their pharmacist/doctor how Mefa Tablet may affect their liver. Mefa Tablet conversion to its active form may be reduced in patients with impaired liver function, which may lead to liver failure. A dosage reduction may be required in some patients.

Heart Disease

Long-term use of Mefa Tablet may increase the risk of a heart attack in patients with pre-existing heart conditions or heart failure. It is not used for treating pain after coronary bypass surgery.

Gastrointestinal Disorders

Long term use of Mefa Tablet can cause damage to the stomach and intestine. Serious conditions like bleeding, ulceration, and perforation of the stomach or intestinal wall can occur. Any symptom indicating ulceration and bleeding like chronic indigestion, the appearance of coffee coloured dry blood in stools or vomiting of blood should be reported immediately.
Food interactions
Information not available.
Lab interactions

Diazo test for urinary bile

Treatment with Mefa Tablet may give a false-positive result for this test. It is advised to inform the doctor and lab technician about the consumption of this medicine before the test is performed.
Take Mefa Tablet as advised by the doctor. Never take more than the prescribed dose. Take this medicine at the same time every day. Do not give your medicine to other people even if their condition appears to be the same as yours.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
Dicyclomine relaxes the muscles in the stomach and intestine to stop sudden muscle spasms, thereby relieves pain, cramps and discomfort. Mefenamic acid stops the release of a chemical called prostaglandins, that increase pain and swelling. Thus, Mefa Tablet provides relief from your aches or cramps and makes you feel better.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Anticholinergics/antispasmodics, Non-steroidal anti-inflammatory agents

Schedule

Schedule H

PCD | Franchise | Manufacturing. 2021. PCD | Franchise | Manufacturing. [online] Available at: < [Accessed 12 April 2021].

https://biotichealthcare.com/pharma-products/mefenamic-acid-and-dicyclomine-hydrochloride-tablets/>

Drugbank.ca. 2021. Dicyclomine | DrugBank Online. [online] Available at: < [Accessed 12 April 2021].

https://www.drugbank.ca/drugs/DB00804>

Drugbank.ca. 2021. Mefenamic acid | DrugBank Online. [online] Available at: < [Accessed 20 April 2021].

https://www.drugbank.ca/drugs/DB00784>

Pubchem.ncbi.nlm.nih.gov. 2021. Dicyclomine. [online] Available at: < [Accessed 12 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Dicyclomine>

Pubchem.ncbi.nlm.nih.gov. 2021. Mefenamic acid. [online] Available at: < [Accessed 12 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Mefenamic-acid>
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Information on this page was last updated on 24 May 2021

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