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Malaclor-Ec 500 MG Tablet

Manufactured byUnicure India Pvt. Ltd.
ContainsChloroquine
Description

Malaclor-Ec 500 MG Tablet is an antimalarial medication which is used for the treatment as well as prophylaxis of malaria. This medicine is also used to treat amebiasis which is a parasitic infection that affects the intestine and amebic liver abscess caused by Entamoeba histolytica. Liver function and blood cell count monitoring is necessary while receiving this medicine. It may also be used for the treatment of rheumatoid arthritis (a joint disorder) in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

Side effects

Major & minor side effects for Malaclor-Ec 500 MG Tablet

  • Blurred vision
  • Confusion
  • Diarrhea
  • Dizziness
  • Skin rash
  • Hair loss
  • Increased sensitivity of the skin to sunlight
  • Double vision

Uses of Malaclor-Ec 500 MG Tablet

What is it prescribed for?

  • Malaria prophylaxis
  • Malaria
  • Amebiasis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed in 1 to 2 hours.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to chloroquine, 4-aminoquinolones, or any other inactive ingredients present in the formulation.

Retinal or visual field changes

This medicine is not recommended for use in patients with any vision impairment due to the risk of worsening of the patient's condition.

Psoriasis

This medicine is not recommended for use in patients with active psoriasis (a skin disorder characterized by dry and scaly patches) as it may worsen the patient's condition.

Porphyria

This medicine is not recommended for use in patients with porphyria (a condition where there is an excess buildup of porphyrin in the body) as it may worsen the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

QT interval prolongation

This medicine should be used with extreme caution in patients suffering from QT prolongation due to the increased risk of worsening of the patient's condition. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Eye disorders

This medicine may increase the risk of vision problems. This effect depends on the dose and duration of the treatment. Close monitoring of eye function is necessary. Any symptoms of a vision problem should be reported to the doctor.

Blood cell count

This medicine may lower the blood cell count if taken for a longer time. Close monitoring of complete blood cell count is necessary. Discontinue the treatment if any signs of low blood cell count appear. It should be used with caution in patients with glucose-6 phosphate dehydrogenase deficiency.

Hearing problem

This medicine may increase the risk of hearing problems and hence should be used with extreme caution in patients with existing auditory defects or problems. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Impaired liver function

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Hypoglycemia

This medicine may lower the blood sugar levels drastically in some patients. Close monitoring of the blood sugar levels, appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Driving or operating machinery

This medicine may cause dizziness, tiredness, visual disturbances, etc. in some patients. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery if you experience any of these symptoms during treatment with this medicine.

Other uses

Your doctor may prescribe this medicine for indications other than those stated above in certain specific circumstances, especially if other medicines are not effective. All the risks and benefits should be discussed with the doctor in such cases.

Missed Dose

If you miss a dose of this medicine, take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Ethambutol

Fluconazole

Tramadol

Quinidine

Chlorpromazine

Disease interactions

Oculotoxicity

This medicine is not recommended in patients with retinal or visual field changes. The treatment should be discontinued if any symptoms of blurred vision, light flashes, and streaks, difficulty in reading, etc. An alternative treatment option should be considered based on the clinical condition.

Seizures

This medicine should be used with caution in patients with seizures due to the increased risk of severe adverse effects. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Liver impairment

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine as advised by your doctor. Do not take in larger amounts than advised. It is advised to take this medicine at the same time every day. Do not stop taking the medicine without consulting your doctor. Ensure that the course of treatment is completed to prevent the spread of infection. Consult the doctor if you experience any undesirable effects
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by increasing the concentration of a toxic molecule in the malarial parasite thus inhibits the growth of the parasite.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Antimalarial Quinolines

Schedule

Schedule H

[Internet]. 2017 [cited 2 May 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/2272

DailyMed - Chloroquine phosphate tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 2 May 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=06c69e2b-211b-4746-9f3a-f86d36520570

[Internet]. Accessdata.fda.gov. 2019 [cited 26 September 2019]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/006002s043lbl.pdf

[Internet]. Medicines.org.uk. 2019 [cited 26 September 2019]. Available from:

https://www.medicines.org.uk/emc/files/pil.5490.pdf
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Information on this page was last updated on 3 Oct 2019

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