Magnesium Valproate

Description

Magnesium Valproate is used either alone or in a combination with other medicines to control and prevent seizures, control extreme mood swings (mania) in patients suffering from bipolar disorder, and to control migraine headaches. This medicine also has the potential to treat cancer.

Side effects

Major & minor side effects for Magnesium Valproate

  • Nausea and vomiting
  • Diarrhea
  • Abdominal pain
  • Increased appetite
  • Weight gain
  • Sleepiness
  • Shakiness in the legs, arms, hands, or feet
  • Itching and rash
  • Hair loss
  • Aggression or anger
  • Weakness

Uses of Magnesium Valproate

What is it prescribed for?

  • Epilepsy
  • Mania
  • Migraine prevention
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, difficulty in concentration, drowsiness, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to magnesium valproate, valproic acid, or any other inactive ingredients present along with this medicine.

Liver Disease

This medicine is not recommended for use in patients suffering from liver diseases due to the increased risk of serious adverse effects.

Urea cycle disorders

This medicine is not recommended for use in patients suffering from urea cycle disorders (high levels of ammonium in the blood) due to the increased risk of serious adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Pediatric use

This medicine may be used for the treatment of children if the benefits significantly outweigh the risks and only under the supervision of a qualified healthcare professional.

Driving and operating machinary

This medicine may cause symptoms such as weakness, drowsiness, sleepiness, dizziness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating heavy machinery if you experience any of these symptoms during treatment with this medicine.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose should be skipped. Do not use extra medicine to make up for the missed dose.

Overdose

Contact your doctor immediately or seek emergency medical intervention if an overdose is suspected. Symptoms of an overdose may include sleepiness, heart block, coma, etc.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, difficulty in concentration, drowsiness, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Lamotrigine

Ethinyl Estradiol

Warfarin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food, as advised by your doctor. Do not take in larger or smaller amounts than advised. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
It restores the balance of certain natural substances in the brain to control and prevent the symptoms of seizures, mania, and migraine headaches.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Anticonvulsants, Antimigraine agents

Schedule

Schedule H

[Internet]. Medind.nic.in. 2018 [cited 3 August 2018]. Available from:

http://medind.nic.in/daa/t09/i1/daat09i1p126.pdf

[Internet]. Tajapi.com. 2018 [cited 3 August 2018]. Available from:

http://www.tajapi.com/Magnesium%20Valproate_CONSUMER%20INFORMATION.htm

Valproate magnesium [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 31 August 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Magnesium_valproate#section=InChI

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Information on this page was last updated on 31 Aug 2018

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.