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Lower TG (10/160 mg) Tablet

Manufactured byPANACEA BIOTEC LTD
ContainsAtorvastatin (10 mg) + Fenofibrate (160 mg)
Description

Lower TG (10/160 mg) Tablet is a combination medicine used for the treatment of combined hyperlipidemia in patients with normal kidney and liver function. Patients are advised to maintain a strict exercise and diet regimen along with this medicine for the best possible effect.

Side effects

Major & minor side effects for Lower TG (10/160 mg) Tablet

  • Difficulty in breathing
  • Chills and fever
  • Itching and skin rash
  • Nausea and Vomiting
  • Headache
  • Shortness of breath
  • Weakness
  • Stuffy Nose
  • Increased sensitivity of the skin to sunlight
  • Cough
  • Difficulty in swallowing
  • Diarrhea
  • Joint pain
  • Muscle pain
  • Difficulty in falling or staying asleep

Uses of Lower TG (10/160 mg) Tablet

What is it prescribed for?

  • Combined hyperlipidemia
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The anti-hypercholesteremic effect of this medicine is cumulative and may take up to 3 to 5 days to show its results.
  • How long do the effects of this medicine last?
    The time until which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women due to the increased risk of fetal harm. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to fenofibrate, atorvastatin, or any other inactive ingredients present along with these medicines.

Renal dysfunction

This medicine is not recommended for use in patients with renal diseases due to the increased risk of severe adverse effects.

Gallbladder disease

This medicine is not recommended for use in patients with a known history of gallbladder diseases due to the increased risk of gallbladder stones.

Liver disease

This medicine is not recommended for use in patients with active liver diseases or any abnormality in the liver function tests due to the increased risk of severe adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women due to the increased risk of fetal harm. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Altered blood sugar levels

This medicine may cause an alteration in the blood sugar levels. This risk is especially higher in patients with diabetes mellitus. Close monitoring of blood sugar levels may be necessary based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Muscle degradation and Rhabdomyolysis

This medicine may cause muscle breakdown and rhabdomyolysis in some patients, a condition which can be fatal. This may cause symptoms such as severe tiredness and weakness. This risk is especially higher in the elderly population and in patients with active muscle disorders. Report any unusual symptoms to the doctor immediately. Replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Alcohol consumption

This medicine may cause liver and kidney injuries in patients consuming alcohol very frequently and in large quantities. Hence, consumption of alcohol should be avoided during treatment with this medicine.

Use in pediatrics

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Stroke

This medicine is not recommended for use in patients recovering from a stroke since it may worsen the patient's condition. Replacement with a suitable alternative should be considered under your doctor's supervision.

Cholelithiasis

This medicine should be used with caution due to the increased risk of gallbladder stones. This risk is especially higher in patients with a history of liver or gallbladder diseases. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Hematologic Changes

This medicine should be used with caution due to the risk of a decrease in the hemoglobin, hematocrit, and white blood cell counts. Close monitoring of complete blood counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Increase in serum creatinine levels

Close monitoring of renal function is recommended in patients receiving this medicine due to the increased risk of elevated serum creatinine levels. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Concomitant Oral Anticoagulants

This medicine should be used with caution in patients receiving anticoagulants due to the increased risk of excessive bleeding. Close monitoring of prothrombin time and INR, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Cognitive impairment

This medicine may cause forgetfulness, memory loss, confusion, etc. in some patients. These side effects are reversible and usually disappear once the medicine is discontinued.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clarithromycin

Erythromycin

Azithromycin

Atazanavir

Cyclosporine

Hypoglycemic agents

Disease interactions

Cognitive Impairment

This medicine should be used with caution in patients with cognitive impairment due to the increased risk of worsening of the patient's condition. Close monitoring of the patient for any changes in mood or behavior is recommended. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Diabetes

This medicine should be used with caution in patients with diabetes mellitus due to the increased risk of altered blood sugar levels. Close monitoring of blood sugar levels is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Rhabdomyolysis

This medicine is not recommended for use in patients with a known history of Rhabdomyolysis due to the increased risk of renal failure and death. Any symptoms such as muscle pain, weakness, or joint pain and swelling should be reported to the doctor on priority. Replacement with a suitable alternative should be considered under your doctor's supervision.
Food interactions
Consumption of grapefruit juice is not recommended during treatment with this medicine due to the increased risk of adverse effects such as dizziness, muscle pain, fever and chills, headache, swelling of hands and feet, vomiting, skin rash, etc.
Lab interactions
Information not available.
Take this medicine as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Atorvastatin reduces the level of cholesterol in the blood. Fenofibrate increases the natural lipid breakdown process with the help of the enzyme lipoprotein lipase. This removes the bad cholesterol (LDL) and triglycerides from the blood and increases the levels of good cholesterol (HDL).
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Statins, Fibric acid derivatives, Antihyperlipidemic combinations

Schedule

Schedule H

DailyMed - Fenofibrate tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 4 August 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f8f09ab1-74db-4123-b85a-6337dc2582a0

Fenofibrate: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 4 August 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a601052.html

DailyMed - Atorvastatin calcium tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 6 October 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=901550e6-22be-68c9-eb86-f85a9c9dd998

Atorvastatin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 6 October 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a600045.html

[Internet]. 2017 [cited 4 August 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/28612

[Internet]. 2017 [cited 23 February 2017]. Available from:

https://www.medicines.org.uk/emc/PIL.2498.latest.pdf
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Information on this page was last updated on 7 May 2018

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