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Lotegate Eye Drops
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Lotegate Eye Drops

Manufactured byAJANTA PHARMA LTD
ContainsLoteprednol (0.5 %w/v) + Gatifloxacin (0.3 %w/v)
Description
Lotegate Eye Drops is a combination of Loteprednol and Gatifloxacin. It is indicated for the treatment or prevention of postoperative eye infections caused by bacteria. Lotegate Eye Drops works by inhibiting the growth and multiplication of the bacteria and by blocking the action of substances that cause redness, pain, and swelling. Lotegate Eye Drops may cause side effects like eye irritation, dryness, burning, or stinging sensation. Most of these symptoms resolve with time as your body gets used to the medicine. Consult your doctor if these symptoms persist or worsen. Lotegate Eye Drops is meant for external use only. Use this medicine as per the dose and duration prescribed by your doctor. Ensure that you complete the course of treatment to prevent the risk of re-infection. This medicine is not effective for the treatment of infections caused by viruses or fungi. Lotegate Eye Drops is not recommended for use if you are allergic to it. Inform your doctor if you have an active or a history of eye conditions like cataracts (clouding of the lens of the eyes leading to blurred vision) or glaucoma (an eye condition that may occur due to increased pressure in the eyes leading to vision loss) before using this medicine. Lotegate Eye Drops is not recommended for use in children below 18 years of age due to the lack of sufficient safety data. If you are pregnant or are breastfeeding, consult your doctor before using this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Lotegate Eye Drops

  • Eye irritation
  • Blurred vision
  • Burning or stinging sensation at application site
  • Redness of the eye
  • Dry eyes

Uses of Lotegate Eye Drops

What is it prescribed for?

  • Steroid-responsive inflammatory ocular conditions
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for Lotegate Eye Drops to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which Lotegate Eye Drops remains active in your body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Lotegate Eye Drops.
  • Can this medicine be taken during pregnancy?
    Lotegate Eye Drops is not recommended for use during pregnancy unless necessary due to the lack of sufficient safety data. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Lotegate Eye Drops is not recommended for use while breastfeeding unless necessary due to the lack of sufficient safety data. Consult your doctor if you are breastfeeding.

Allergic reaction

Lotegate Eye Drops is not recommended for use if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Viral/Fungal eye infections

Lotegate Eye Drops does not treat eye infections caused by viruses or fungi. Hence this medicine is not recommended for use if you have active viral or fungal infections as it may worsen your condition.
Warnings for special population

Pregnancy

Lotegate Eye Drops is not recommended for use during pregnancy unless necessary due to the lack of sufficient safety data. Consult your doctor if you are pregnant.

Breast-feeding

Lotegate Eye Drops is not recommended for use while breastfeeding unless necessary due to the lack of sufficient safety data. Consult your doctor if you are breastfeeding.
General warnings

Contamination

To prevent contamination, avoid touching the tip of the dropper against your eye or other surfaces. Keep the bottle tightly closed when not in use.

Contact lenses

Consult your doctor for the use of contact lenses after eye surgery. If your doctor does recommend the use of contact lenses post-surgery, they should be removed prior to the administration of Lotegate Eye Drops. Wait for 15 minutes before putting them back on the eyes.

Driving vehicles or operating machines

Use of Lotegate Eye Drops may cause temporary blurring of the vision immediately after instilling the medicine. Avoid performing activities such as driving vehicles or operating machines until your vision is clear.

Use in Children

Lotegate Eye Drops is not recommended for use in children below 18 years of age due to a lack of sufficient safety and efficacy data.

Drug-resistance

Use Lotegate Eye Drops for the recommended duration to prevent antibiotic resistance (a condition where microorganisms develop the ability to defeat the antibiotics intended to kill them.)

Missed Dose

Administer the missed dose of Lotegate Eye Drops as soon as you remember. If it is time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

As Lotegate Eye Drops is intended for external use, the likelihood of side effects due to an overdose is low. However, do not instill more than the prescribed dose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Ketorolac

Bromfenac

Disease interactions

Ocular Toxicities

Lotegate Eye Drops should be used with extreme caution if you have a history of cataracts (clouding of the lens of the eyes leading to blurred vision) or glaucoma (an eye condition with abnormally high pressure inside the eye that may eventually lead to loss of vision), as it may worsen your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Lotegate Eye Drops is meant for use on the eyes only. Use Lotegate Eye Drops as instructed by your doctor. Wash your hands before each use. Avoid touching the tip of the dropper against your eyes or other surfaces to prevent contamination. Avoid sharing your eye drops with others. Do not use Lotegate Eye Drops in larger or smaller quantities than prescribed. Consult your doctor if you experience any undesirable effects that persist or worsen. Ensure that you complete the course of treatment. Do not stop the use of this medicine without consulting your doctor. Wait for at least ten minutes before administering any other eye drops or eye medication in the same eye to avoid dilution. Consult your doctor before using contact lenses after eye surgery. Do not instill this medicine while wearing contact lenses. Keep this medicine out of reach of children and pets. Use it within a month after opening the bottle.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Lotegate Eye Drops is a combination of Loteprednol and Gatifloxacin. Loteprednol works by reducing the formation of certain substances in the body that are responsible for causing redness, swelling, and pain. Gatifloxacin works by stopping the growth and multiplication of the bacteria and eventually killing them.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Ophthalmic steroids with anti-infectives, Ophthalmic preparations

Schedule

Schedule H

Medlineplus.gov. 2021. Gatifloxacin Ophthalmic: MedlinePlus Drug Information. [online] Available at: < [Accessed 23 December 2021].

https://medlineplus.gov/druginfo/meds/a605012.html>

Medlineplus.gov. 2021. Loteprednol Ophthalmic: MedlinePlus Drug Information. [online] Available at: < [Accessed 23 December 2021].

https://medlineplus.gov/druginfo/meds/a619025.html>

Accessdata.fda.gov. 2021. ZYMAR® (gatifloxacin ophthalmic solution) 0.3%. [online] Available at: < [Accessed 23 December 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021493s006,007lbl.pdf>

Medicines.org.uk. 2021. Lotemax 0.5% w/v Eye Drops, Suspension - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 23 December 2021].

https://www.medicines.org.uk/emc/product/6212/smpc#gref>
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Information on this page was last updated on 28 Dec 2021

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