Lomefloxacin

Description

The primary ingredient of Lomefloxacin is available as both ophthalmic and oral form. The oral form of this medicine is used to treat a variety of conditions such as respiratory tract infections, urinary tract infections, etc. caused by susceptible strains of bacteria. The ophthalmic form of this medicine is used for the treatment of bacterial conjunctivitis caused by susceptible bacterial species. This medicine is not recommended for use in cases of a common cold, flu, or other viral infections since it is active only against infections caused by bacteria.

Side effects

Major & minor side effects for Lomefloxacin

  • Headache
  • Nausea
  • Dizziness
  • Abdominal pain
  • Fatigue
  • Dry mouth
  • Increased sweating
  • Muscle pain
  • Dark urine
  • Burning and stinging of eye
  • Eye pain
  • Itching of the eye
  • Blurred vision

Uses of Lomefloxacin

What is it prescribed for?

  • Acute exacerbation of chronic bronchitis
  • Cystitis
  • Complicated urinary tract infections
  • Infection prophylaxis
  • Bacterial Conjunctivitis
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/administering this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/administering this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.

Allergy

This medicine is not recommended for use in patients with a known allergy to lomefloxacin, any other fluoroquinolones, or any other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/administering this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking/administering this medicine. If the medicine is used, the infant should be monitored closely for any adverse effects.
General warnings

Photosensitivity

This medicine may make you more sensitive to sunlight or tanning lights. You are advised to use sunscreen and wear protective clothing to avoid adverse reactions to sunlight during treatment with this medicine.

Driving or Operating machinery

Use of this medicine may cause symptoms such as blurred vision, confusion, dizziness, etc. in some patients. It is advised that you do not perform any activities such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Drug-resistance

Usage of this medicine without sufficient proof or suspicion of a bacterial infection should be avoided. Irrational dosing might fail in providing benefits and may even cause toxicity. It may also increase the risk of development of bacteria that are drug resistant.

Diarrhea

Antibiotic therapy will cause an imbalance in the normal microbial flora of the large intestine, which may promote the growth of a bacteria called Clostridium difficile and you may experience severe diarrhea as a result. Report any such incidence to the doctor on priority and avoid usage of this medicine in such cases.

Epilepsy

This medicine should be used with caution in patients with epilepsy due to the increased risk of worsening the patient's condition. Appropriate dose adjustments or replacements with a suitable alternative may be required based on the clinical condition.

Kidney impairment

This medicine should be used with caution in patients with an impaired kidney function due to the increased risk of severe adverse effects. Close monitoring of kidney function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Tendinitis and tendon rupture

Use of this medicine will increase the risk of developing tendinitis or tendon rupture during the treatment or several months after the treatment. This may affect your shoulders, hands, ankles, or other parts of your body. You are at a higher risk if you are more than 60 years of age or if you have undergone a transplant of kidney, heart, or lung. You are also at a higher risk if you are on corticosteroids such as dexamethasone, methylprednisolone, or prednisone. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

QT prolongation

This medicine should be used with extreme caution in patients with a history of QT prolongation due to the increased risk of worsening of the patient's condition. This risk is especially higher in patients with heart diseases or electrolyte disturbances and elderly patients. Report any incidence of discomfort in the chest, heart palpitations, etc., to the doctor on priority. Close monitoring of heart function and vital signs, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Other medicines

Lomefloxacin may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Missed Dose

Tablet: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one. Eye Drops: Administer the missed dose as soon as you remember. It is advisable to skip the missed dose if it is almost time for your next scheduled dose. Do not instill a double dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Aluminium Hydroxide/Magnesium Hydroxide

Probenecid

Cimetidine

Warfarin

Disease interactions

Central nervous system disorders

This medicine should be used with extreme caution in patients with a history of seizure disorder and other central nervous system abnormalities since it may worsen the patient's condition. Report any incidence of tremors, restlessness, anxiety, confusion, hallucinations, etc., to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Renal impairment

This medicine should be used with caution in patients with renal diseases due to the increased risk of severe adverse effects. Report any unusual symptoms to the doctor immediately. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Tablet: Take this medicine with or without food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. Eye Drops: Use this medicine exactly as prescribed. Do not administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by inhibiting an enzyme required for the bacterial DNA to replicate. This blocks the multiplication and growth and results in the eventual death of the bacteria.
Legal Status

Approved

Unknown

Approved

Unknown

Classification

Category

Quinolones

Schedule

Schedule H

Lomefloxacin - DrugBank [Internet]. Drugbank.ca. 2018 [cited 12 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB00978

Lomefloxacin [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 12 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/lomefloxacin

Lomefloxacin tablets - PillPack [Internet]. Pillpack.com. 2018 [cited 12 September 2018]. Available from:

https://www.pillpack.com/medication/lomefloxacin-tablets

[Internet]. Meppo.com. 2018 [cited 12 September 2018]. Available from:

http://www.meppo.com/pdf/drugs/1270-OKACIN-1441016457.pdf

[Internet]. Beximcopharma.com. 2018 [cited 12 September 2018]. Available from:

http://www.beximcopharma.com/images/stories/product-pdf/Contra.pdf

[Internet]. Accessdata.fda.gov. 2018 [cited 12 September 2018]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/20013s015lbl.pdf

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Information on this page was last updated on 21 Mar 2019

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We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.