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Lodoz 2.5 Tablet
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Lodoz 2.5 Tablet

Manufactured byMERCK INDIA LTD
ContainsBisoprolol (2.5 mg) + Hydrochlorothiazide (6.25 mg)
Description
Lodoz 2.5 Tablet is a combination of Bisoprolol and Hydrochlorothiazide. It is used in the treatment of hypertension (abnormally high blood pressure). It also prevents further chances of heart attack (the flow of blood to the heart is blocked) and stroke (a brain condition that occurs due to disruption in blood supply to the brain). This medicine works by eliminating excess water and salt from your body. It also relaxes the blood vessels and improves blood flow. Lodoz 2.5 Tablet shows common side effects such as cough, headache, diarrhoea, stomach upset, nausea, and tiredness. These side effects usually subside with time. However, consult your doctor for further assistance if they persist or worsen. Avoid driving vehicles or operating heavy machines if you feel dizzy after taking this medicine. Lodoz 2.5 Tablet may be taken with or without food. Do not chew, crush, or break the tablet. Swallow it whole with a glass of water. Take the tablet at the same time daily for the ease of remembering. Avoid the consumption of alcohol while taking the medicine as it can cause side effects such as low blood pressure, irregular heartbeats, etc. Lodoz 2.5 Tablet is not recommended if you are allergic to it. Avoid taking the medicine if you have heart failure (inability of the heart to pump sufficient blood throughout the body), slow heartbeats, AV block (electrical signals that control heartbeat are disturbed causing slow or irregular heartbeat), or anuria (a condition in which the kidney is unable to produce urine). Lodoz 2.5 Tablet should be used with caution if you have liver or kidney problems, glaucoma (an eye condition that causes an increase in fluid pressure within the eyes), thyroid problem (abnormal production of hormones by the thyroid gland), or diabetes (high blood sugar level). Consult your doctor if you have any other medical conditions or taking any medications before starting the treatment with Lodoz 2.5 Tablet. Lodoz 2.5 Tablet is not recommended for use in children below 18 years of age due to insufficient safety and efficacy data. Consult your doctor if you are pregnant or breastfeeding before taking the medicine.
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Side effects

Major & minor side effects for Lodoz 2.5 Tablet

  • Diarrhoea
  • Joint pain
  • Heartburn
  • Stomach discomfort
  • Chest pain
  • Troubled breathing
  • Unusual tiredness or weakness
  • Dizziness
  • Cough

Uses of Lodoz 2.5 Tablet

What is it prescribed for?

  • Mild to moderate hypertension
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Lodoz 2.5 Tablet starts showing its effect within two hours of intake.
  • How long do the effects of this medicine last?
    Lodoz 2.5 Tablet remains effective in the body for approximately 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Avoid consumption of alcohol while taking Lodoz 2.5 Tablet as it may increase the risk of side effects.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for Lodoz 2.5 Tablet.
  • Can this medicine be taken during pregnancy?
    Lodoz 2.5 Tablet is not recommended for use during pregnancy unless necessary. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Lodoz 2.5 Tablet may pass into breastmilk. Hence if you are breastfeeding, consult your doctor before taking this medicine.

Allergy

Avoid taking Lodoz 2.5 Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Cardiogenic shock

Cardiogenic shock is an emergency condition where your heart suddenly stops pumping blood throughout your body. Lodoz 2.5 Tablet is not recommended in such cases as it may further worsen your condition.

Heart block greater than first degree/ AV block

Heart block is when your heartbeats are abnormally slow or irregular. First-degree heart block is the least severe, second-degree heart block is severe and can often progress to third-degree heart block, the most severe form. Lodoz 2.5 Tablet is not recommended if you have a heart block greater than the first degree as it may worsen your condition.

Sinus Bradycardia

Bradycardia or slow heartbeat is when your heart beats less than 60 times per minute. Lodoz 2.5 Tablet is not recommended if you have sinus bradycardia as it may worsen your condition.

Anuria

Anuria is a condition in which your kidney is unable to produce urine. Lodoz 2.5 Tablet is not recommended for use if you have anuria as it may worsen your condition.

Overt heart failure

Lodoz 2.5 Tablet is not recommended if you have severe heart failure (inability of the heart to pump sufficient blood throughout the body) with predominant symptoms, as it can worsen your condition.
Warnings for special population

Pregnancy

Lodoz 2.5 Tablet is not recommended for use during pregnancy unless necessary. Consult your doctor if you are pregnant.

Breast-feeding

Lodoz 2.5 Tablet may pass into breastmilk. Hence if you are breastfeeding, consult your doctor before taking this medicine.
General warnings

Hyperuricaemia

Lodoz 2.5 Tablet should be used with caution if you have hyperuricaemia (an excess of uric acid in the blood) as this medicine decreases uric acid excretion from the body.

Liver condition

Lodoz 2.5 Tablet should be used with extreme caution if you have liver problems due to an increase in the risk of serious side effects. Report any symptoms of confusion or jaundice (yellow skin discolouration due to an increased level of a yellowish substance called bilirubin in the blood) to your doctor on priority.

Lupus erythematosus

Lupus erythematosus is a serious condition that occurs when the immune system attacks your own body causing swelling, fatigue, joint pain, rash, fever, etc. Lodoz 2.5 Tablet should be used with caution if you have or have had lupus erythematosus, as it may further trigger or aggravate such condition.

Thyroid condition

Lodoz 2.5 Tablet should be used with caution if you have a thyroid condition (abnormal production of hormones by the thyroid gland, a butterfly-shaped gland located at the base of the neck). Follow all the instructions given by your doctor. Avoid discontinuing this medicine without consulting your doctor.

Surgery

Lodoz 2.5 Tablet can interact with anaesthesia and affect the functioning of the heart, which is not suitable for major surgery. Inform your doctor about this medicine if you plan to undergo any kind of surgery.

Use in children

Lodoz 2.5 Tablet is not recommended for use in children below 18 years of age.

Driving vehicles or operating machines

Avoid driving vehicles or operating machines if you feel dizzy after taking Lodoz 2.5 Tablet.

Kidney conditions

Lodoz 2.5 Tablet should be used with caution if you have kidney problems due to the increased risk of undesired effects. Your doctor may suggest tests to monitor your kidney functions and recommend dose adjustments based on your clinical condition.

Heart Failure

Lodoz 2.5 Tablet may further weaken the contractions of your heart and slow down the heart rate. Hence it should be avoided if you have heart failure (inability of the heart to pump sufficient blood throughout the body). Consult your doctor before taking this medicine.

Alteration in blood volume and electrolyte levels

Lodoz 2.5 Tablet should be used with caution as it may alter the blood volume and electrolyte levels in your body. Your doctor may monitor your electrolyte levels and blood pressure periodically during treatment with this medicine. Report any symptoms such as weakness, lethargy, dry mouth muscle pain, drowsiness, dizziness, irregular heartbeat, etc., to your doctor immediately.

Missed Dose

Do not miss the scheduled dose of Lodoz 2.5 Tablet. In case you miss a dose, take the medicine as soon as you remember. If it is almost time for your next dose, then skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Do not take more than the recommended dose of Lodoz 2.5 Tablet. Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Avoid consumption of alcohol while taking Lodoz 2.5 Tablet as it may increase the risk of side effects.
Interaction with Medicine

Insulin

Alprazolam

Theophylline

Diltiazem

Disease interactions

Asthma

Lodoz 2.5 Tablet should be used with caution if you have asthma (narrowing of the airways leading to breathing difficulty) as this medicine can cause constriction of the airways. Consult your doctor before taking this medicine.

Glaucoma

Glaucoma is an eye condition caused due to increased pressure within the eyes, which may lead to vision loss. Lodoz 2.5 Tablet may lower the pressure within your eyes, hence it should be used with caution if you are taking medicines to treat glaucoma.

Diabetes

Diabetes refers to high blood sugar levels in the body. Lodoz 2.5 Tablet should be used with caution if you have diabetes as this medicine cause an alteration in blood sugar levels. Monitor your blood sugar levels regularly while you are taking this medicine.
Food interactions
Multivitamins with minerals may decrease the effectiveness of Lodoz 2.5 Tablet if taken together. It is advised to have at least two hours gap between the administration of these two medicines. Follow all the instructions given by your doctor.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Lodoz 2.5 Tablet with or without food. Take this tablet at the same time daily for ease of remembering. Do not chew, crush, or break the tablet. Swallow it whole with a glass of water. Never take more than the prescribed dose. Do not discontinue the medicine without consulting with your doctor. Avoid the consumption of alcohol while taking Lodoz 2.5 Tablet, as it may increase the risk of side effects. Take the medicine with caution if you have kidney or liver conditions. Avoid sharing your medicine with others even if their condition appears to be the same as yours.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Lodoz 2.5 Tablet is a combination of Bisoprolol and Hydrochlorothiazide. Bisoprolol works by relaxing the blood vessels and reducing the heart rate, thus promoting a smooth flow of blood. Hydrochlorothiazide works by eliminating excess water and salt from your body.
Legal Status

Approved

Approved

Unknown

Unknown

Classification

Category

Beta blockers with thiazides, Antihypertensive combinations

Schedule

Schedule H

Accessdata.fda.gov. 2022. [online] Available at: [Accessed 13 July 2022].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020186s027s028lbl.pdf

nhs.uk. 2022. Bisoprolol: medicine to treat high blood pressure (hypertension). [online] Available at: [Accessed 13 July 2022].

https://www.nhs.uk/medicines/bisoprolol/
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Information on this page was last updated on 1 Aug 2022

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