Home >
Medicine Info >
LO-E Tablet
Loading interface...

LO-E Tablet

Manufactured byEast West Pharma
ContainsEnalapril (5 mg) + Losartan (25 mg)
Description
LO-E Tablet is a combination medicine which may be used for the treatment of high blood pressure and other heart complications. You are advised to take this medicine with a proper diet and regular exercise regimen for optimal control of the blood pressure.
QUICK LINKS:
Side effectsConcernsUsage

Side effects

Major & minor side effects for LO-E Tablet

  • Stomach pain
  • Difficulty or painful urination
  • Fast heartbeat
  • Back pain
  • Dizziness
  • Nasal congestion
  • Sore throat
  • Drowsiness
  • Headache
  • Cough
  • Constipation
  • Diarrhea
  • Low blood pressure (hypotension)
  • Blurred vision
  • Chest pain
  • Fever or chills
  • Vomiting
  • Skin rash

Uses of LO-E Tablet

What is it prescribed for?

  • Hypertension
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of this medicine can be observed within 1 hour of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to losartan, enalapril or any other inactive ingredients present in the formulation.

Aliskiren

Coadministration of aliskiren and this medicine is not recommended due to the increased risk of serious adverse effects. This risk is especially higher in the elderly population and in patients with diabetes and kidney diseases.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women except in life-threatening conditions. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Hypotension

This medicine should be used with caution in patients who are sodium depleted and/or volume depleted by diuretic use since it may increase the risk of hypotension. The volume depleted and/or sodium depleted state should be corrected before starting the therapy or the treatment should be started at a lower dose. Vital signs should be monitored closely during therapy with this medicine.

Hyperkalemia

Use of this medicine may increase the potassium levels in the blood (hyperkalemia). This may cause serious side effects such as fatal cardiac rhythm irregularities. It is advised to avoid potassium-rich foods (potatoes, bananas) and other medicines that may increase potassium levels (ACE inhibitors and potassium supplements) during treatment with this medicine.

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests, appropriate dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Kidney Disease

This medicine should be used with caution in patients with kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Driving or operating machinery

Use of this medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Cough

This medicine may cause a persistent nonproductive cough in some patients which will be resolved when the medicine is discontinued.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of side effects such as dizziness, lightheadedness, and fainting. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol during treatment with this medicine.
Interaction with Medicine

Dexamethasone

Captopril

Insulin

Nonsteroidal anti-inflammatory medicines

Benazepril

Perindopril

Disease interactions

Congestive heart failure

This medicine should be with caution in patients with congestive heart failure since it may worsen the patient's condition. Close monitoring of heart function, blood pressure, and kidney function is recommended for such patients. Replacement with a suitable alternative may be required based on the clinical condition.

Angioedema

This medicine is not recommended for use in patients with a known history of angioedema due to the increased risk of worsening of the condition. Report any symptoms such as swelling of the face or lips, difficulty swallowing, or difficulty breathing to the doctor immediately. Replacement with a suitable alternative may be required based on the clinical condition.
Food interactions
It is recommended to avoid a high potassium diet during treatment with this medicine due to the increased risk of serious adverse effects. Your doctor/dietitian will suggest appropriate changes in your diet to avoid high intake of potassium.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take this medicine exactly as advised by your doctor. It can be taken with or without food. Do not take in larger amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Enalapril and Losartan both relax the blood vessels and promote a smooth flow of the blood. Their combination is thus effective in reducing the blood pressure.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Antihypertensive combinations, Angiotensin receptor blockers, Angiotensin converting enzyme inhibitors

Schedule

Schedule H

Enalapril: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 27 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a686022.html

Losartan: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 8 March 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a695008.html

[Internet]. 2017 [cited 8 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/8320

[Internet]. 2017 [cited 27 March 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/25937
Loading related questions...
Something doesn’t feel right?
Report an error

Information on this page was last updated on 16 Jul 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.