Lincomycin

Description

Lincomycin is an antibiotic medicine used in treating bacterial infections. It is available in different dosage forms such as a capsule, syrup/suspension, injection and gel. The oral and injectable forms of this medicine are used to treat bacterial infections of the lungs, skin, bones, joints, stomach, and intestine. The topical form is used to treat acne. Lincomycin stops the growth of bacteria that causes infection. Lincomycin is an antibacterial medicine, hence it is not effective against infections caused by viruses. Lincomycin may cause certain side effects like diarrhoea, stomach pain, headache, skin rash, itching/irritation, weakness, nausea, and vomiting. Contact your doctor if these side effects become severe or persist for a longer duration. Avoid using Lincomycin if you are allergic to it. The capsule forms of Lincomycin are not recommended for use in children below 12 years of age. Lincomycin is one of the effective antibiotics given to infants, children and adults. Lincomycin should be taken on an empty stomach in a dose prescribed by your doctor. Lincomycin injectables will be given by your doctor in the hospital setting. For topical forms, apply the required amount of this medicine to the affected area as advised by your doctor. Make sure to complete the treatment course because stopping the antibiotic treatment abruptly may develop resistance. This may relapse your infection. Lincomycin should be used with caution if you have gastrointestinal problems, particularly colitis (swelling of the inner lining of the colon) as it may cause severe diarrhoea making your condition worse. This medicine may not be suitable for all people. Inform your doctor if you have kidney or liver problems before taking this medicine. Also, inform your doctor if you are pregnant or breastfeeding before initiating the treatment.

Side effects

Major & minor side effects for Lincomycin

  • Stomach pain
  • Diarrhoea
  • Nausea
  • Fast heartbeat
  • Skin rash and itching
  • Vomiting
  • Headache
  • Skin irritation
  • Pain at the injection site
  • Dry skin
  • Weakness

Uses of Lincomycin

What is it prescribed for?

  • Bacterial infections
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Concerns

Commonly asked questions

  • Onset of action
    The onset of action for each dosage form is as follows: Oral forms (capsules) - Exact onset of action is not known. However, improvement can be noticed within 2-3 days of treatment. Parenteral forms (injections) - Action starts within 30-60 minutes. Topical forms (gel) - Improvement can be seen within 2-6 weeks of treatment.
  • Duration of effect
    The duration of action for injection forms of Lincomycin is about 36 hours. The duration of action for oral and topical forms of Lincomycin is not known.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendency has been reported for Lincomycin.
  • Usage in pregnancy?
    Lincomycin is not known to cause birth defects when taken in pregnancy. However, consult your doctor before using this medicine.
  • Usage while breast-feeding?
    Lincomycin is not known to be harmful in breastfeeding. It passes into breast milk in very small amounts. However, consult your doctor before using this medicine. If you are using this medicine, the baby should be observed for symptoms such as diarrhoea and diaper rash.

Allergy

Do not use Lincomycin if you are allergic to it. Inform your doctor if there is a history of lincomycin allergy. If you notice any symptoms such as skin rash, itching/swelling, dizziness, breathing difficulties, etc., seek medical attention immediately.
Warnings for special population

Pregnancy

Lincomycin is not known to cause birth defects when taken in pregnancy. However, consult your doctor before using this medicine.

Breast-feeding

Lincomycin is not known to be harmful in breastfeeding. It passes into breast milk in very small amounts. However, consult your doctor before using this medicine. If you are using this medicine, the baby should be observed for symptoms such as diarrhoea and diaper rash.
General warnings

Diarrhoea

Lincomycin may kill the helpful bacteria in your stomach or intestine which can lead to diarrhoea. Get emergency medical help if you experience severe diarrhoea that is watery or bloody.

Gasping syndrome

Use of Lincomycin injection containing benzyl alcohol may cause a gasping syndrome in newborn babies.

Antibiotic resistance

Finish the complete course of treatment with Lincomycin, even if your condition improves. Abrupt stopping of antibiotic treatment may not kill all the bacteria and the remaining bacteria may become resistant to the antibiotic.

Skin reactions

Lincomycin may cause serious skin reactions characterised by rash, peeling skin, swelling of your face or tongue, skin blisters in or around your nose, mouth, and eyes. Discontinue the medicine and inform your doctor if you experience these symptoms.

External use only

The topical forms of lincomycin are recommended for external use only. Avoid direct contact with eyes, mucous membranes, or open wounds.

Use in children

Lincomycin capsule forms are not recommended for use in children below 12 years of age, since the safety and efficacy data is not available.

Missed Dose

Oral forms: Try not to skip a scheduled dose of Lincomycin. In case the scheduled dose of Lincomycin is forgotten, take it as soon as you remember. If it got delayed for more than 12 hours, skip the missed dose and take your next dose at the usual time, but do not double the dose. Injectable forms: It is always important to take your lincomycin injection at a scheduled time. If you missed taking the dose, inform your doctor as soon as you remember, and get an appointment for further instructions. Topical forms: Apply the missed dose of lincomycin gel as soon as you remember. Do not apply in more quantities to compensate for the missed dose.

Overdose

Oral forms: Never take more than the prescribed dose. Seek emergency medical treatment or contact your doctor in case you suspect an overdose of Lincomycin. Injectable form: Lincomycin injection is administered in a hospital setting by your doctor, so the likelihood of an overdose is rare. Contact your doctor if an overdose with Lincomycin is suspected. Topical forms: An overdose of Lincomycin is not likely to cause severe symptoms unless it is applied for a long duration and in large quantities. However, swallowing this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Erythromycin

Ethinyl Estradiol

Live attenuated vaccines and related products

Disease interactions

Gastro-intestinal disease

If you have a gastrointestinal issue, such as swelling of your colon (large intestine), inform your doctor before taking Lincomycin. This medicine can lead to diarrhoea and further can make your condition worse.

Liver disease

Lincomycin is broken down and absorbed in the liver. Use this medicine with caution if you have pre-existing liver problems as it may accumulate in your liver and lead to serious side effects.

Kidney diseases

Lincomycin should be used with caution if you have pre-existing kidney problems as it may lead to kidney damage. Your doctor may adjust the dose of this medicine based on your clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Oral forms: Lincomycin tablet is used to treat bacterial infections. Take it on an empty stomach in a dose and duration prescribed by your doctor. Complete the entire course of treatment. For the ease of remembering, take it around the same time every day. Do not share your medicine with others even if their condition appears to be the same as yours. Your doctor may advise a blood test to check for kidney and liver enzyme levels. Discontinue the medicine if persistent diarrhoea occurs. Injectable forms: Lincomycin injection will be given to the vein in the hospital setting by your doctor. Hence do not self-administration. Topical forms: Lincomycin gel is recommended for external use only. Avoid contact with your eyes, mucous membranes, or open wounds. In case of accidental contact, wash with water thoroughly. Apply a thin layer of Lincomycin to the affected area as instructed by your doctor. Finish the entire course of treatment even if your symptoms improve after a few days.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Lincomycin works by stopping the bacterial protein synthesis that is essential for its growth. Thus it kills or stops the growth of bacteria.
Legal Status

Approved

Approved

Approved

Unknown

Classification

Category

Lincomycin derivatives

Schedule

Schedule H

Dailymed.nlm.nih.gov. 2021. DailyMed - LINCOMYCIN- lincomycin hydrochloride injection, solution. [online] Available at: < [Accessed 10 March 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=61f4851d-d919-400d-912a-05eb9dca11d4#LINK_ba4a4806-d761-4b46-97ff-f604f1373d42>

Pubchem.ncbi.nlm.nih.gov. 2021. Lincomycin. [online] Available at: < [Accessed 12 March 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Lincomycin>

Tajpharma.com. 2021. Lincozin Hcl Inj, Taj Products Manufacturing, Pharmaceutical products, Products Exporters, Products Sellers, free download Lincozin Hcl Inj pdf, free download Lincozin Hcl Inj doc, free download Lincozin Hcl Inj documents, Lincozin Hcl Inj pharmaceutical formulations, beauty products, pharmaceutical companies, Indian pharma products, Indian Manufacturers of Pharmaceutical Products,Lincozin Hcl Inj Manufacturer, Lincozin Hcl Inj Pharmaceutical Product Manufacturers, Products Supplier, Products Development, Products Exporters, Products Sellers. [online] Available at: < [Accessed 20 August 2021].

https://tajpharma.com/lincozin%20Hcl%20Inj-taj-products.htm>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 20 August 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/050317s179s180lbl.pdf>

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Information on this page was last updated on 23 Nov 2021

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