Levobunolol

Description

Levobunolol is used for the treatment of increased fluid pressure inside the eye (intraocular hypertension) and open-angle glaucoma, a progressive condition that may eventually lead to vision loss. This medicine is not recommended for use in patients below 18 years of age.

Side effects

Major & minor side effects for Levobunolol

  • Burning and stinging of eye
  • Discharge from eyes
  • Redness of the eye
  • Blurred vision
  • Eye pain
  • Unusual drowsiness
  • Unusual tiredness or weakness
  • Sweating
  • Irregular heartbeat
  • Dizziness when getting up suddenly from a sitting position

Uses of Levobunolol

What is it prescribed for?

  • Intraocular hypertension
  • Open angle Glaucoma
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Concerns

Commonly asked questions

  • Onset of action
    The effect of this medicine can be observed within one hour of administration of the dose.
  • Duration of effect
    The effect of this medicine lasts for an average duration of 24 hours.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to levobunolol or any other inactive ingredients present along with it.

Asthma/COPD

This medicine is not recommended for use in patients suffering from Asthma/COPD due to the increased risk of worsening of the patient's condition.

Cardiogenic shock

This medicine is not recommended for use in patients suffering from cardiogenic shock due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
General warnings

Use in children

This medicine is not recommended for use in children below 18 years of age since the safety and efficacy of use are not clinically established.

Cerebrovascular insufficiency

This medicine should be used with caution in patients with conditions that obstruct the blood supply to the brain due to the increased risk of worsening of the existing condition. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the patient's condition.

Contact lens

Based on the severity of your symptoms, your doctor may advise you to avoid the use of contact lenses. If you are allowed to use contact lenses, remove them prior to the administration of the eye drops. They can be reinserted 15 minutes post administration.

Driving or Operating macinery

Use of this medicine may cause symptoms such as blurred vision, fatigue, drowsiness, etc. in some patients. If you experience any of these symptoms, it is advised that you do not perform any activities such as driving a vehicle or operating machinery until your symptoms clear.

WADA Category-P2 - Beta-Blockers (Sports)

Athletes are advised not to indulge in certain sports while using this medicine. Archery, racing, shooting and other high-risk sports should be avoided. Sportspersons should refer to the list of medicines published by the World Anti-Doping Agency (WADA) which are not to be taken while participating in specific sports events.

Corneal diseases

This medicine should be used with caution in patients suffering from diseases that affect the cornea, a layer that covers the front part of the eye, since it medicine may induce dryness of the eyes. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Missed Dose

Administer the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Formoterol

Epinephrine

Salmeterol

Verapamil

Aminophylline

Diltiazem

Disease interactions

Congestive heart failure

This medicine is not recommended for use in patients suffering from congestive heart failure due to the increased risk of worsening of the patient's condition. Close monitoring of clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Diabetes Mellitus

This medicine should be used with caution in patients suffering from diabetes mellitus due to the increased risk of altered blood glucose levels. Close monitoring of blood glucose levels, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.

Hyperthyroidism

This medicine should be used with caution in patients suffering from hyperthyroidism since it may mask some signs and symptoms of this condition in few patients. Close monitoring of thyroid hormone levels, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Use this medicine exactly as prescribed. Do not administer in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by reducing the fluid pressure inside the eyes.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Ophthalmic glaucoma agents

Schedule

Schedule H

Levobunolol - DrugBank [Internet]. Drugbank.ca. 2018 [cited 7 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB01210

[Internet]. Allergan.com. 2018 [cited 7 September 2018]. Available from:

https://www.allergan.com/assets/pdf/betagan_pi

Levobunolol Ophthalmic: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 7 September 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a686011.html

Levobunolol [Internet]. Pubchem.ncbi.nlm.nih.gov. 2018 [cited 7 September 2018]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/levobunolol

[Internet]. Mhra.gov.uk. 2018 [cited 7 September 2018]. Available from:

http://www.mhra.gov.uk/home/groups/spcpil/documents/spcpil/con1515128692791.pdf

Betagan - Summary of Product Characteristics (SmPC) - (eMC) [Internet]. Medicines.org.uk. 2019 [cited 8 January 2019]. Available from:

https://www.medicines.org.uk/emc/product/857/smpc

DailyMed - Levobunolol Hydrochloride- levobunolol hydrochloride solution/ drops [Internet]. Dailymed.nlm.nih.gov. 2019 [cited 8 January 2019]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5ab1efbe-530b-4787-b40a-c7dbf18161e1

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Information on this page was last updated on 8 Jan 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.