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Letromac 2.5 MG Tablet
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Letromac 2.5 MG Tablet

Manufactured byMacleods Pharmaceuticals Pvt. Ltd.
ContainsLetrozole
Description
Letromac 2.5 MG Tablet is a medicine used in the treatment of breast cancer in postmenopausal women (women who have not had periods for more than a year marking the end of menstrual cycles). This medicine works by decreasing the levels of oestrogen in your body. Letromac 2.5 MG Tablet may cause side effects such as tiredness, loss of appetite, joint pain and stiffness, nausea/vomiting, dizziness, diarrhoea, constipation, increased sweating, etc. Consult your doctor if these symptoms persist or if they become severe. Letromac 2.5 MG Tablet is taken once a day, with or without food. Do not break, chew, or crush the tablet. Swallow it whole with a glass of water. Take it at the same time every day to maintain a constant level of this medicine in your body and for ease of remembering. Do not discontinue the medicine without consulting your doctor. Letromac 2.5 MG Tablet is not recommended if you are allergic to it. Inform your doctor if you have a history of osteoporosis (a condition with weak and brittle bones), high cholesterol levels, or pre-existing liver problems before taking this medicine. It is not recommended for use if you are pregnant or breastfeeding.
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Side effectsConcernsUsage

Substitutes

List of substitutes for Letromac 2.5 MG Tablet

Fertolet 2.5 MG Tablet
Cipla Ltd.
Letoval 2.5 MG Tablet
Sun Pharma Laboratories Ltd.
Letroz 2.5 MG Tablet
Sun Pharma Laboratories Ltd.
Ovulet 2.5 MG Tablet
Bharat Serums & Vaccines Ltd.
Stimufol 2.5 MG Tablet
Intas Pharmaceuticals Ltd.

Side effects

Major & minor side effects for Letromac 2.5 MG Tablet

  • Hot flushes (sudden feeling of heat)
  • Increased cholesterol levels
  • Fatigue
  • Increased sweating
  • Joint pain
  • Loss of appetite
  • Nausea or Vomiting
  • Indigestion
  • Diarrhoea or Constipation
  • Weight gain
  • Increased blood pressure
  • Abdominal pain
  • Dry mouth
  • Depression
  • Headache
  • Dizziness
  • Hair loss
  • Skin Rash
  • Muscle pain
  • Tiredness
  • Swelling of hands, feet, and ankles
  • Vaginal bleeding
  • Joint stiffness

Uses of Letromac 2.5 MG Tablet

What is it prescribed for?

  • Breast cancer
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The time required by Letromac 2.5 MG Tablet to show its effect is not clinically known.
  • How long do the effects of this medicine last?
    The amount of time for which Letromac 2.5 MG Tablet remains active in your body is not known.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies have been reported with Letromac 2.5 MG Tablet.
  • Can this medicine be taken during pregnancy?
    Letromac 2.5 MG Tablet is unsafe for use during pregnancy. Hence consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    Letromac 2.5 MG Tablet is not recommended for use during breastfeeding.

Allergy

Avoid taking Letromac 2.5 MG Tablet if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc., after taking this medicine.

Premenopausal women

Menopause is defined as the permanent end of menstrual cycles in women. Letromac 2.5 MG Tablet is not recommended for use in premenopausal women (women who have not experienced menopause and those who are still having regular/irregular periods).
Warnings for special population

Pregnancy

Letromac 2.5 MG Tablet is unsafe for use during pregnancy. Hence consult your doctor if you are pregnant.

Breast-feeding

Letromac 2.5 MG Tablet is not recommended for use during breastfeeding.
General warnings

Menopausal status

Menopause is defined as the permanent end of menstrual cycles in women. Only women of postmenopausal status should take Letromac 2.5 MG Tablet. In case of unclear menopausal status, consult the doctor before initiating treatment with Letromac 2.5 MG Tablet.

Other medicines

Letromac 2.5 MG Tablet may interact with other medicines and cause undesired effects. Hence, inform your doctor about your current medicines, including any herbs and supplements, before beginning treatment with this medicine.

Driving or operating machines

Letromac 2.5 MG Tablet may cause dizziness. Avoid driving vehicles or operating machines if you feel dizzy while taking this medicine.

Missed Dose

Try not to skip a dose of Letromac 2.5 MG Tablet. Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double the dose to compensate for a missed one.

Overdose

Do not take more than the prescribed dose. Contact your doctor if you suspect an overdose with Letromac 2.5 MG Tablet.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Clobazam

Ethinyl Estradiol

Hydroxyprogesterone

Citalopram

Clopidogrel

Fenofibrate

Disease interactions

Liver Disease

Letromac 2.5 MG Tablet is broken down by your liver and should be used with caution if you have pre-existing liver problems due to the increased risk of undesired effects, resulting from the accumulation of this medicine in your body. Your doctor may suggest tests to monitor your liver function during treatment with this medicine.

Hypercholesterolemia

Hypercholesterolaemia is a condition with high blood cholesterol (fats) levels. Letromac 2.5 MG Tablet may increase your risk of hypercholesterolaemia and should be used with caution if you have increased blood cholesterol levels. Your doctor may suggest tests to monitor your blood cholesterol levels during treatment with this medicine.

Osteoporosis

Osteoporosis is a condition in which your bones become weak and brittle. It also increases your risk of bone fractures. Letromac 2.5 MG Tablet should be used with caution as it may increase your risk of osteoporosis.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take Letromac 2.5 MG Tablet as directed by your doctor. It may be taken with or without food. Do not take more or less than the prescribed dose. Avoid discontinuation of Letromac 2.5 MG Tablet without consulting your doctor. Letromac 2.5 MG Tablet may cause dizziness. Do not drive vehicles or operate machines if you feel dizzy while taking this medicine. Letromac 2.5 MG Tablet may increase your blood cholesterol levels. Your doctor may closely monitor your blood cholesterol levels while on treatment with this medicine. Anti-cancer medicines are usually very strong and can have many side effects. Discuss with your doctor to understand all the benefits and risks before starting the treatment. Consult your doctor if you experience any side effects that persist or become severe.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
Letromac 2.5 MG Tablet works by blocking an enzyme (aromatase) that is involved in the production of oestrogens. This results in decreased levels of oestrogen in your body and thereby slows down or stops the growth of cancer cells.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Aromatase inhibitors, Anticancer drug

Schedule

Schedule H

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https://www.medicines.org.uk/emc/product/9957/smpc

Accessdata.fda.gov. 2021. [online] Available at: [Accessed 27 October 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020726s027lbl.pdf

Ebs.tga.gov.au. 2021. TGA eBS - Product and Consumer Medicine Information Licence. [online] Available at: [Accessed 27 October 2021].

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2009-PI-00261-3

Drugs, H., 2021. Letrozole: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: [Accessed 27 October 2021].

https://medlineplus.gov/druginfo/meds/a698004.html

Rad-ar.or.jp. 2021. Search results detail| Kusurino-Shiori(Drug information Sheet). [online] Available at: [Accessed 27 October 2021].

https://www.rad-ar.or.jp/siori/english/kekka.cgi?n=38226
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Information on this page was last updated on 13 Sep 2022

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