Lenograstim

Description

Lenograstim is a human granulocyte colony-stimulating factor (G-CSF) analog. It stimulates the growth of white blood cells and helps in decreasing the chances of infection in patients who are undergoing chemotherapy procedures for cancer. Patients with blood disorders are advised not to use this medicine.

Side effects

Major & minor side effects for Lenograstim

  • Nausea and Vomiting
  • Diarrhea
  • Stomach pain
  • Constipation
  • Fever
  • Tiredness
  • Chest pain
  • Muscle pain
  • Back pain
  • Headache
  • Dizziness
  • Shortness of breath
  • Cough

Uses of Lenograstim

What is it prescribed for?

  • Neutropenia caused by chemotherapy
  • Bone Marrow Transplantation
  • Peripheral Progenitor Cell Transplantation
  • Severe congenital neutropenia
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit forming tendency has been reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Lenograstim or other inactive ingredients present along with it.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Liver Diseases

This medicine should be used with caution in patients suffering from liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Kidney Diseases

This medicine should be used with caution in patients suffering from kidney diseases due to the increased risk of severe adverse effects. Close monitoring of kidney function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Infections

This medicine should be used with extreme caution in patients with latent or active infections since it may worsen the patient's condition. This risk is especially higher in patients on high doses of this medicine for a prolonged period of time. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Sickle cell crisis

This medicine should be used with extreme caution in patients with sickle cell disease due to the increased risk of serious and life-threatening reactions. Discuss the risks and benefits with your doctor before receiving this medicine. Replacement with a suitable alternative might be required based on the clinical condition.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Cyclophosphamide

Vinorelbine

Vincristine

Vinblastine

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Your dose regimen and frequency of administration is likely to vary based on the condition being treated. Consult your doctor immediately if you develop any signs and symptoms of an infection.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine works by stimulating the production of white blood cells and thus helps to fight against infections.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Colony stimulating factors, Haemotopoietic agents

Schedule

Schedule H

Lenograstim - DrugBank [Internet]. Drugbank.ca. 2019 [cited 28 March 2019]. Available from:

https://www.drugbank.ca/drugs/DB13144

[Internet]. Medicines.org.uk. 2019 [cited 28 March 2019]. Available from:

https://www.medicines.org.uk/emc/files/pil.1577.pdf

[Internet]. Medicines.org.uk. 2019 [cited 28 March 2019]. Available from:

https://www.medicines.org.uk/emc/files/pil.7806.pdf

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Information on this page was last updated on 22 May 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.