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L-Ther Tablet
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L-Ther Tablet

Manufactured byLEBEN LIFE SCIENCES PVT. LTD.
ContainsArtemether (80 mg) + Lumefantrine (480 mg)
Description
L-Ther Tablet is an antimalarial medicine that consists of Artemether and Lumefantrine. It is used to treat malaria when other antimalarial medications become ineffective. This medicine works by killing the parasite causing malaria and prevents the spread of infection. L-Ther Tablet should not be used in severe malaria (vital organs like brain, lungs, kidneys, etc. are involved) or in the prevention of malaria. L-Ther Tablet may cause side effects like headache, loss of appetite, weakness, joint/muscle pain, fever, nausea, vomiting, etc. Consult your doctor if these side effects are troubling you. Avoid driving or doing any activity that requires mental focus as this medicine can make you feel dizzy. L-Ther Tablet should be taken with food or as prescribed by your doctor. Take plenty of water to avoid any stomach irritation. You should not skip any doses. Complete the whole course to see the maximum benefits. Avoid discontinuation of this medicine without consulting your doctor as the symptoms may reappear. It may also make it more difficult to treat your infection. L-Ther Tablet is not recommended if you have a known allergy to it. Inform your doctor about all the medicines you are taking as they can interact with L-Ther Tablet and reduce its therapeutic effect. L-Ther Tablet is not used in pregnancy or for breastfeeding women unless prescribed by your doctor. If you have any medical conditions of the liver, kidney, or any other health conditions, then report them to your doctor. Your doctor may adjust your dose to safely use this medicine.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for L-Ther Tablet

  • Stomach pain and cramps
  • Nausea and Vomiting
  • Diarrhoea
  • Itching and skin rash
  • Dizziness and lightheadedness
  • Ringing or buzzing in the ears
  • Increased heartbeat
  • Muscle and joint pain
  • Sleep disturbances
  • Weight loss
  • Shaking and trembling of arms and feet
  • Decrease/loss of hearing
  • Headache
  • Loss of appetite
  • Fever
  • Weakness

Uses of L-Ther Tablet

What is it prescribed for?

  • Malaria
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    It is not known when L-Ther Tablet will start its action after oral administration.
  • How long do the effects of this medicine last?
    It is not known how long L-Ther Tablet remains effective in your body.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported for L-Ther Tablet.
  • Can this medicine be taken during pregnancy?
    L-Ther Tablet is not recommended for use in pregnancy, especially in the first trimester as it may harm your developing foetus. Consult your doctor if you are pregnant.
  • Can this medicine be taken while breast-feeding?
    L-Ther Tablet is not recommended while breastfeeding unless absolutely necessary. This medicine may be passed into breastmilk which may affect your baby. All the risks and benefits should be discussed with your doctor before using this medicine.

Allergy

Avoid taking L-Ther Tablet if you are allergic to it. Taking this medicine in such cases could lead to symptoms such as shortness of breath, swelling of the face, lips, tongue, or other parts of your body, rash, itching, or hives (itchy, painful eruptions that sting) on your skin, etc. Ask for another suitable medicine in such cases.
Warnings for special population

Pregnancy

L-Ther Tablet is not recommended for use in pregnancy, especially in the first trimester as it may harm your developing foetus. Consult your doctor if you are pregnant.

Breast-feeding

L-Ther Tablet is not recommended while breastfeeding unless absolutely necessary. This medicine may be passed into breastmilk which may affect your baby. All the risks and benefits should be discussed with your doctor before using this medicine.
General warnings

Drug resistance

It is important to take L-Ther Tablet for the entire prescribed duration even if you feel better after some doses. If you fail to do so, the parasite will change over time and no longer respond to the medicine. Hence, further treatment of infection with this medicine would become difficult.

Severe complicated malarial infection

L-Ther Tablet is not recommended for use if you have a severe and complicated malarial infection. In this form of malaria, many vital organs like the brain, lungs, kidney, etc are involved and often result in organ failure and abnormalities in your blood.

Hormonal contraceptives

L-Ther Tablet may interact and alter the effectiveness of hormonal contraceptives. Hence, alternative or additional means of contraception may be necessary based on your clinical condition.

QT prolongation

L-Ther Tablet should be used with extreme caution if you have heart conditions such as QT prolongation (electrical disturbance in the heart) as this medicine can alter your heartbeats. Be cautious if you have other heart problems or are taking any other medicine that might prolong the QT intervals. Your doctor may adjust the dose and/or frequently monitor your heart functions to use this medicine safely.

Missed Dose

Take the missed dose of L-Ther Tablet as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

If you have consumed more than the prescribed amount of L-Ther Tablet then you may experience complications like breathing difficulties, lightheadedness, fainting, loss of coordination, fast heartbeats, etc. Consult a doctor immediately so that overdose treatment can be initiated.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Erythromycin

Quinidine

Chlorpromazine

Ciprofloxacin

Quetiapine

Terfenadine

Doxorubicin

Doxepin

Azithromycin

Citalopram

Duloxetine

Disease interactions

Liver Disease

Use L-Ther Tablet with caution if you have severe liver impairment. Consult your doctor if you have any concerns.

Kidney Disease

Use L-Ther Tablet with caution if you have severe kidney impairment. Consult your doctor if you have any concerns.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Take L-Ther Tablet with food or milk for better absorption of this medicine. Take L-Ther Tablet as prescribed by your doctor and complete the whole course. However, if your symptoms do not improve or worsen, consult your doctor. Avoid discontinuation of this medicine without consulting your doctor. If you vomit within 1 to 2 hours after taking L-Ther Tablet, take another full dose of this medicine. Contact your doctor if you vomit again after taking the extra dose. L-Ther Tablet may cause dizziness so do not do any activity that requires mental focus like driving. Do not stand up too fast as it can make you feel dizzy. Avoid consuming alcohol while taking this medicine as it can worsen your dizziness.
Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works
L-Ther Tablet is a combination of two antiparasitic medicines: Artemether and Lumefantrine, which treats malaria. These medicines work by interacting with haeme (a component of haemoglobin protein) in the blood. This results in the formation of substances toxic to the malarial parasite. Thus, it kills the parasite and prevents the spread of infection.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Antimalarial combinations

Schedule

Schedule H

[Internet]. 2018 [cited 9 August 2018]. Available from:

https://www.researchgate.net/publication/272021944_THE_NEW_80480_MG_TABLET_FORMULATION_OF_ARTEMETHER-LUMEFANTRINE_COARTEM_R_IS_BIOEQUIVALENT_TO_A_DOSE_OF_FOUR_INDIVIDUAL_STANDARD_TABLETS_IN_HEALTHY_VOLUNTEERS_LB-223

Medicines.org.uk. 2021. Riamet 20 mg/120 mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 9 August 2021].

https://www.medicines.org.uk/emc/product/1628>

Dailymed.nlm.nih.gov. 2021. DailyMed - COARTEM- artemether and lumefantrine tablet. [online] Available at: < [Accessed 9 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=7866ec19-dfac-47d4-a53f-511a12643cbf>
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Information on this page was last updated on 21 Oct 2021

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