L-Methylfolate

Description

L-Methylfolate is a naturally occurring form of vitamin B necessary for maintaining some very important functions in the body. It is used as an adjunctive in treating the decreased folate levels or hyperhomocysteinemia (high levels of amino acid) in patients with schizophrenia or depression. It is also used for treating certain anemias caused due to the deficiency of folate. This medicine is not recommended for use in patients below 18 years of age.

Side effects

Major & minor side effects for L-Methylfolate

  • Confusion
  • Nausea
  • Difficulty in concentrating
  • Bitter taste
  • Sleeplessness
  • Abdominal distension
  • Excitement

Uses of L-Methylfolate

What is it prescribed for?

  • Folic acid deficiency
  • Schizophrenia
  • Major depressive disorder
  • Megaloblastic Anemia
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Concerns

Commonly asked questions

  • Onset of action
    The amount of time required for this medicine to show its action is not clinically established.
  • Duration of effect
    The amount of time for which this medicine remains effective in the body is clinically not established.
  • Safe with alcohol?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to L-Methylfolate or any other inactive ingredients present in the formulation.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
General warnings

Vitamin B12 Deficiency anemia

This medicine should not be used alone to treat an anemic patient with a history of vitamin B12 deficiency due to the increased risk of worsening the patient's condition.

Use in Children

This medicine is not recommended for use in patients below 18 years of age since the safety and efficacy of use are not clinically established.

Missed Dose

Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Fluorouracil

Fosphenytoin

Capecitabine

Phenytoin

Carbamazepine

Methotrexate

Primidone

Disease interactions

Bipolar disorder

This medicine should be used with caution in patients with bipolar disorder due to the increased risk of alterations in mood. Report any unusual symptoms to the doctor on priority. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine with or without food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine is essential for the production of certain vital components that are necessary for the maintenance of normal body functions.
Legal Status

Approved

Approved

Unknown

Approved

Classification

Category

Vitamins

Schedule

Schedule H

Levomefolic acid - DrugBank [Internet]. Drugbank.ca. 2019 [cited 8 January 2019]. Available from:

https://www.drugbank.ca/drugs/DB11256

l-methylfolate [Internet]. Cardiosmart.org. 2019 [cited 8 January 2019]. Available from:

https://www.cardiosmart.org/Healthwise/d057/73/d05773

L-METHYLFOLATE CALCIUM 7.5mg Tablets L-METHYLFOLATE CALCIUM 15mg Tablets [Internet]. Dailymed.nlm.nih.gov. 2019 [cited 8 January 2019]. Available from:

https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=76386336-417d-4f90-8171-1f745198ded2&type=display

[Internet]. Intetlab.com. 2019 [cited 8 January 2019]. Available from:

http://intetlab.com/uploads/pub/Deplin_PackageInsert.pdf

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Information on this page was last updated on 11 Sep 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.