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Ketriplin Cream
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Ketriplin Cream

Manufactured byAJANTA PHARMA LTD
ContainsAmitriptyline (4 %w/w) + Ketamine (2 %w/w)
Description
Ketriplin Cream is a combination medicine used for the treatment of patients suffering from neuralgia. This medicine is not recommended for use if you are known allergic to it.
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Side effectsConcernsUsage

Side effects

Major & minor side effects for Ketriplin Cream

  • Redness of skin
  • Pale skin
  • Dry skin
  • Itching and rash

Uses of Ketriplin Cream

What is it prescribed for?

  • Neuralgia
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to Amitriptyline, Ketamine or any other inactive ingredients present in the formulation.

Monoamine oxidase inhibitors (MAO)

This medicine is not recommended for use in patients taking monoamine oxidase inhibitors (MAOI) due to the increased risk of serious and life-threatening side effects. A time gap of at least 14 days should be maintained between stopping therapy with MAOIs and starting therapy with this medicine.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
General warnings

Application area specific dose

Application of high doses in areas where chances of absorption are higher (e.g., face, armpit, groin, etc.) should be avoided. Systemic absorption may result in severe adverse effects.

Allergic skin reaction

Use of this medicine may cause local allergic skin reactions such as a rash, erythema, pinpoint spots, etc. in some patients. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Use in Children

This medicine is not recommended for use in patients below 12 years of age since the safety and efficacy of use are not clinically established. However, your doctor may prescribe this medicine if the benefits significantly outweigh the risks. In such a case, the patient should be monitored closely for any adverse effects.

External use only

This medicine is recommended for external use only. Avoid contact with the eyes, mucous membranes, or open wounds.

Other medicines

This medicine may interact with many other medicines and may cause severe adverse effects. Hence, it is advised that you inform the doctor about all your current medicines including any herbs and supplements before beginning treatment with this medicine.

Missed Dose

Apply the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not apply a double dose to make up for the missed dose.

Overdose

An overdose of this medicine is not likely to cause severe symptoms unless it is applied for a prolonged period of time in large volumes. However, ingestion of this medicine may cause harm and immediate medical intervention may be required.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine
Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Apply a thin layer of the cream to the affected area as instructed by the doctor. Follow all the usage instructions mentioned on the label or the package insert. Do not apply in larger or smaller quantities than recommended. Do not cover the application area with bandages or other coverings unless specifically instructed by the doctor.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works
Amitriptyline is believed to work by increasing the concentration of norepinephrine and serotonin which are the two primary chemical messengers in the brain and Ketamine blocks the receptors in the body, preventing the sensation of pain from reaching the brain.
Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Tricyclic antidepressants, General anesthetics

Schedule

Schedule H

[Internet]. Drugbank.ca. 2018 [cited 3 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB00321

[Internet]. Sullivan-painresearch.mcgill.ca. 2018 [cited 3 September 2018]. Available from:

http://sullivan-painresearch.mcgill.ca/pdf/abstracts/sullivanoct2005_2.pdf

[Internet]. Drugbank.ca. 2018 [cited 3 September 2018]. Available from:

https://www.drugbank.ca/drugs/DB01221
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Information on this page was last updated on 8 May 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.