Ketoprofen

Description

Ketoprofen is used to relieve pain, tenderness, swelling and stiffness in conditions such as osteoarthritis and rheumatoid arthritis. It is also used to relieve minor aches and pains from headaches, menstrual periods, toothaches, the common cold, fever, muscle aches, backaches, etc.

Side effects

Major & minor side effects for Ketoprofen

  • Indigestion
  • Dizziness
  • Headache
  • Nausea
  • Diarrhea
  • Rash
  • Abdominal pain
  • Mouth sores
  • Nervousness
  • Ringing in ears
  • Difficult or painful urination

Uses of Ketoprofen

What is it prescribed for?

  • Osteoarthritis
  • Rheumatoid Arthritis
  • Dysmenorrhea
  • Mild to moderate pain
  • Ankylosing Spondylitis
  • Pain and inflammation following orthopedic surgery
Read More
Concerns

Commonly asked questions

  • Onset of action
    The amount of time required by this medicine to show its effect is subject to vary based on the route of administration.
  • Duration of effect
    The amount of time for which this medicine remains effective is subject to vary based on the route of administration.
  • Safe with alcohol?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc.
  • Is it habit forming?
    No habit-forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.
  • Usage while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to ketoprofen, other non-steroidal anti-inflammatory medicines, or any other inactive ingredients present along with this medicine.

Severe heart failure

This medicine is not recommended for use in patients with severe heart failure since it may worsen the patient's condition.

Severe Hepatic impairment

This medicine is not recommended for use in patients with severe hepatic impairment due to the increased risk of serious adverse effects.

Severe renal impairment

This medicine is not recommended for use in patients with severe renal impairment due to the increased risk of serious adverse effects.

Skin disorders

The topical forms of this medicine (gel and patch/plaster) are not recommended for use in patients with skin disorders such as eczema, acne, open wounds, skin lesions, dermatosis, etc. due to the increased risk of severe adverse reactions.

Coronary Artery Bypass Surgery (CABG)

This medicine is not recommended for use in patients planning to undergo a coronary artery bypass surgery or patients with a recent heart surgery due to the increased risk of severe adverse reactions.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before using this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Heart disease

This medicine should be used with caution in patients with heart diseases due to the increased risk of adverse effects on the heart, especially after a prolonged use. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Hyperkalemia

This medicine may increase the potassium levels in the blood (hyperkalemia). Report any unusual symptoms to the doctor immediately. Close monitoring of potassium levels may be necessary for some patients. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Hypertension

This medicine should be used with caution in patients with a known history of hypertension due to the increased risk of worsening of the patient's condition. Close monitoring of blood pressure is recommended for such patients. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Gastro-intestinal bleeding

This medicine may cause severe gastrointestinal bleeding and perforation after a prolonged usage. These adverse events may occur with or without warning symptoms. This risk is especially higher in the elderly population and in patients with a history of gastrointestinal diseases. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Female fertility

Use of this medicine may impair female fertility. Discuss all the risks and benefits with your doctor before using this medicine.

Visual disturbances

This medicine may cause visual disturbances in some patients. Discontinue the use of this medicine in case of any visual disturbances and contact your doctor immediately.

Pediatric population

This medicine is not recommended for use in children since the safety and efficacy of use are not clinically established.

Elderly population

This medicine should be used with caution in the elderly population due to the increased risk of severe adverse effects. These patients should be started at lower doses to check for tolerance. Close monitoring of renal and liver function may be necessary for such patients based on the clinical condition.

Missed Dose

Oral forms: If a dose of this medicine is missed, take the dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose and take the next dose. Do not double the dose to make up for the missed one. Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of missing a dose is very low. Gel/Patch/Plaster: If a dose of this medicine is missed, apply the dose as soon as you remember it. If it is almost time for the next dose, skip the missed dose. Do not double the dose to make up for the missed one.

Overdose

Oral forms/Patch/Plaster/Gel: Seek emergency medical treatment or contact the doctor in case of an overdose. Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of serious side effects such as severe gastrointestinal bleeding, dizziness, fatigue, weakness, etc.
Interaction with Medicine

Warfarin

Ketorolac

Prednisolone

ACE inhibitors

Disease interactions

Asthma

This medicine is not recommended for use in patients with a known history of NSAID-induced asthma due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be done under your doctor's supervision.

Anemia

This medicine should be used with caution in patients with a known history of anemia due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition of the patient.

Skin Rash

This medicine may cause fatal skin allergies without any warnings in some patients. Signs and symptoms such as rashes, hives, fever, or other allergic symptoms should be reported to the doctor without any delay. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Gastro-Intestinal toxicity

This medicine may cause damage to the stomach, intestines, liver, etc., especially on prolonged use. Report any symptoms such as chronic indigestion, blood in stool or vomit, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Heart attack and Stroke

This medicine may cause a heart attack, stroke, or other associated symptoms after a prolonged use. This risk is especially higher in patients with a history of heart diseases. Close monitoring of heart function is recommended for such patients. Report any symptoms such as a chest pain, shallow breathing, speech slurring, weakness, etc. to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.

Fluid Retention and edema

This medicine may cause fluid retention and edema in some patients. Close monitoring of blood pressure, electrolyte levels, and heart function may be required based on the clinical condition. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
Oral forms: Take this medicine exactly as prescribed by the doctor. Do not take in larger or smaller quantities than recommended. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. Injection: This medicine should be administered only by a qualified healthcare professional in the clinical or hospital setting. Carefully follow all the instructions given by your doctor. Gel/Patch/Plaster: Use this medicine exactly as prescribed by the doctor. Do not apply in larger or smaller quantities than recommended. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine works by blocking the formation of certain chemical substances in the body which are responsible for causing pain and swelling.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Nonsteroidal anti-inflammatory agents

Schedule

Schedule H

Ketoprofen: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 18 October 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a686014.html

[Internet]. 2017 [cited 18 October 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/25503

DailyMed - Ketoprofen capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 18 October 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c2c99853-1268-4998-a44b-2bf0c0b70fd2

Ketoprofen - DrugBank [Internet]. Drugbank.ca. 2017 [cited 18 October 2017]. Available from:

https://www.drugbank.ca/drugs/DB01009

[Internet]. 2017 [cited 18 October 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/24498

[Internet]. 2017 [cited 18 October 2017]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/019816s011lbl.pdf

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Information on this page was last updated on 30 Oct 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.