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Kenadion-1 Injection

Manufactured bySAMARTH LIFE SCIENCES PVT LTD
Description

Kenadion-1 Injection is a fat-soluble form of Vitamin K which is used for the prevention and control of bleeding associated with a low blood level of prothrombin or factor VII. It is also used for the treatment of patients who are at risk of bleeding during anticoagulant therapy. This vitamin acts as a nutritional supplementation in patients with Vitamin K deficiency (too little vitamin K in the body).

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Side effects

Major & minor side effects for Kenadion-1 Injection

  • Difficulty in breathing
  • Muscle stiffness
  • Yellow eyes or skin
  • Decreased appetite
  • Lightheadedness, dizziness, or fainting
  • Chest pain or discomfort
  • Skin rash
  • Injection site pain
  • Flushing of face
  • Increased sweating

Uses of Kenadion-1 Injection

What is it prescribed for?

  • Hypoprothrombinemia
  • Anticoagulant-Induced Prothrombin Deficiency
  • Hemorrhagic diseases
  • Vitamin K deficiency
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    Oral form: The effect of this medicine can be observed within 6 to 10 hours after the administration of the dose. Parenteral form: The effect of this medicine can be observed within 12 to 14 hours after the administration of the dose.
  • How long do the effects of this medicine last?
    Oral form: The amount of time for which this medicine remains active in the body is not clinically established. Parenteral form: The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendency has been reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after assessing the condition and evaluating the risks and benefits associated with the use of this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.

Allergy

This medicine is not recommended for use if you have a known history of allergy to Phytomenadione or vitamin K supplements.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. Your doctor will determine the best course of treatment after assessing the condition and evaluating the risks and benefits associated with the use of this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.
General warnings

Severe allergic reactions

Severe allergic reactions or hypersensitivity reactions, including anaphylactic shock, low blood pressure, breathing difficulties, urticaria (skin rash), etc. may occur with the use of Kenadion-1 Injection. Appropriate corrective measures or dose adjustments may be required in some cases based on the clinical condition.

Other medicines

Report the use of all medicines including herbs and supplements to the doctor before beginning treatment with this Kenadion-1 Injection.

Missed Dose

Injection: Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low. Tablet: Take the missed dose as soon as you remember. If it is almost time for the next scheduled dose, then the missed dose can be skipped. Do not double the dose to make up for the missed dose.

Overdose

Injection: Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected. Tablet: Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Cholestyramine

Dicumarol

Disease interactions

Hepatic and/or biliary impairment

Conditions like liver and/or biliary impairment may alter the desired effects of Kenadion-1 Injection. Appropriate dose adjustments may be necessary for patients with these medical conditions.
Food interactions
Information not available.
Lab interactions
Information not available.
Injection: This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine. Tablet: Take this medicine following all directions mentioned on the label or as prescribed by the doctor. Do not take in larger or smaller quantities or for longer than recommended.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Does not cause sleepiness

How it works
This medicine helps in the production of clotting factors that are necessary for blood to clot normally in the body.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Anticoagulant reversal agents, Vitamins, Hemostatics

Schedule

Schedule H

Phylloquinone [Internet]. Pubchem.ncbi.nlm.nih.gov. 2019 [cited 5 September 2019]. Available from:

https://pubchem.ncbi.nlm.nih.gov/compound/Phylloquinone

Konakion MM 10 mg/ml - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2019 [cited 5 September 2019]. Available from:

https://www.medicines.org.uk/emc/product/9755/smpc

Phytonadione: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2019 [cited 5 September 2019]. Available from:

https://medlineplus.gov/druginfo/meds/a682659.html

Vitamin K1 - DrugBank [Internet]. Drugbank.ca. 2019 [cited 5 September 2019]. Available from:

https://www.drugbank.ca/drugs/DB01022
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Information on this page was last updated on 5 Sep 2019

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.