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Jotal Tablet

Manufactured byDR. JOHNS LABORATORIES PVT LTD
ContainsChlordiazepoxide (10 mg) + Trifluoperazine (1 mg)
Description
Jotal Tablet is a combination medicine which may be used for the treatment of schizophrenia, a nervous system disorder that affects the patient's ability to think, feel, and behave and anxiety which is characterized by symptoms such as uneasiness, nervousness, extreme fear, persistent worry, etc.

Side effects

Major & minor side effects for Jotal Tablet

  • Fever
  • Dizziness
  • Headache
  • Confusion
  • Sleeplessness
  • Dry mouth
  • Constipation
  • Nausea
  • Vomiting
  • Change in mood
  • Unsteadiness
  • Loss of appetite
  • Shakiness in the legs, arms, hands, or feet
  • Restlessness
  • Decreased interest in sexual intercourse
  • Menstrual changes
  • Skin rash

Uses of Jotal Tablet

What is it prescribed for?

  • Schizophrenia
  • Anxiety
Read More
Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The peak effect of this medicine can be observed within 2 to 4 hours of administration of the dose.
  • How long do the effects of this medicine last?
    The effect of this medicine lasts for an average duration of 3 to 6 days.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as confusion, dizziness, nausea, vomiting, weakness, fainting, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to chlordiazepoxide, trifluoperazine, or any other inactive ingredients present along with the formulation.

CNS Depression

This medicine is not recommended for use in patients suffering from severe central nervous system depression or coma due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.
General warnings

Seizures

This medicine should be used with extreme caution in patients suffering from seizure disorder due to the increased risk of recurrent seizures. Report any unusual symptoms to the doctor immediately. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Driving and Operating machinery

Use of this medicine may cause symptoms such as dizziness, blurred vision, confusion, drowsiness, etc. in some patients. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you experience any of these symptoms during treatment with this medicine.

Dementia

This medicine is not recommended for use in patients suffering from dementia due to the increased risk of serious adverse effects including death. This risk is especially higher in elderly patients. Replacement with a suitable alternative should be considered based on the clinical condition of the patient.

Suicidal tendencies

This medicine should be used with caution due to the increased risk of suicidal tendencies. This risk is especially higher in young adult patients. Patients should be closely monitored for any change in mood or behavior. Report any such incidence to the doctor so that counseling and monitoring of progress can be performed at regular intervals. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Withdrawal symptoms

Abrupt discontinuation of this medicine may increase the risk of adverse effects, especially if you have been using a high dose for a long duration. A gradual dose reduction is recommended to avoid these reactions. Do not stop the use of this medicine without consulting your doctor.

Impaired kidney function

This medicine should be used with extreme caution in patients suffering from kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Missed Dose

Take the missed dose as soon as you remember. If it is almost the time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of severe adverse effects such as confusion, dizziness, nausea, vomiting, weakness, fainting, etc. It is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating machinery if you consume alcohol while taking this medicine.
Interaction with Medicine

Opioids

Antihypertensives

Bupropion

Citalopram

Clozapine

Amiodarone

Bedaquiline

Ceritinib

Disease interactions

Liver Disease

This medicine should be used with extreme caution in patients suffering from liver diseases due to the increased risk of worsening of the patient's condition. Close monitoring of liver function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Neuroleptic Malignant Syndrome (NMS)

This medicine should be used with extreme caution in patients with a history of neuroleptic malignant syndrome due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Close monitoring of the clinical condition, appropriate dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Renal Dysfunction

This medicine should be used with extreme caution in patients suffering from kidney diseases due to the increased risk of worsening of the patient's condition. Close monitoring of kidney function is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Seizure disorders

This medicine should be used with extreme caution in patients suffering from seizure disorder due to the increased risk of worsening of the patient's condition. Report any unusual symptoms to the doctor immediately. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.

Tardive Dyskinesia

This medicine should be used with extreme caution in patients with a history of Tardive Dyskinesia due to the increased risk of recurrent symptoms. This risk is especially higher in elderly female patients. Report any symptoms such as uncontrolled movements of the tongue, mouth, lips, jaw, hands, feet, etc. to your doctor immediately. Appropriate corrective measures, dose adjustments, or replacement with a suitable alternative may be required in some cases based on the clinical condition of the patient.
Food interactions
Information not available.
Lab interactions
Information not available.
Take this medicine exactly as instructed by the doctor. Follow all the labeled instructions while taking this medicine. Ensure that the right quantity of medicine is consumed for the prescribed duration only. Consult the doctor if you experience any undesirable side effects. Ensure that the course of treatment is completed. Do not stop the use of this medicine without consulting your doctor.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

Causes sleepiness

How it works
Chlordiazepoxide works by stabilizing the brain cells and thus reduces the excitability of the brain cells. Trifluoperazine works by inhibiting the release of certain chemical substances in the brain which are responsible for causing anxiety and the symptoms of schizophrenia.
Legal Status

Unknown

Unknown

Unknown

Unknown

Classification

Category

Benzodiazepines, Phenothiazine antipsychotics, Anxiolytic- Antipsychotic agents

Schedule

Schedule H

Trifluoperazine - DrugBank [Internet]. Drugbank.ca. 2018 [cited 26 July 2018]. Available from:

https://www.drugbank.ca/drugs/DB00831

DailyMed - Chlordiazepoxide hydrochloride capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 1 June 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=68c7d8a7-08b3-4a1a-acbd-09bbe67b8d4a

Trifluoperazine: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2018 [cited 26 July 2018]. Available from:

https://medlineplus.gov/druginfo/meds/a682121.html

DailyMed - Trifluoperazine hydrochloride tablet, film coated [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 26 July 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=c2575a86-19e5-44df-8603-ff066bb9c9c5
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Information on this page was last updated on 9 Jul 2019

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