Ivermectin

Description

Ivermectin is an antiparasitic agent which is used in the treatment of worm infections in the intestine and skin.Take this medicine as a single dose on an empty stomach. Do not use in children with weight less than 15 kg.

Side effects

Major & minor side effects for Ivermectin

  • Fever
  • Skin rash
  • Muscle pain
  • Increased heartbeat
  • Headache
  • Swelling of the face, arms, hands, lower legs, or feet
  • Diarrhea
  • Dizziness
  • Loss of appetite
  • Abdominal pain

Uses of Ivermectin

What is it prescribed for?

  • Onchocerciasis
  • Strongyloidiasis
  • Scabies
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Concerns

Commonly asked questions

  • Onset of action
    The peak effect of this medicine for treating onchocerciasis can be observed in 3 to 6 months and for strongyloidiasis in 3 months.
  • Duration of effect
    The medicine stays in the body for an average duration of 2 to 3 days.
  • Safe with alcohol?
    Consumption of alcohol is not recommended in patients receiving Ivermectin. It may increase the concentration of this medicine and can cause skin rash, headache, dizziness, vomiting, diarrhea, and abdominal pain.
  • Is it habit forming?
    No habit forming tendencies were reported.
  • Usage in pregnancy?
    This medicine is not recommended for pregnant women unless necessary. The risk and benefits should be discussed with the doctor before receiving this medicine.
  • Usage while breast-feeding?
    This medicine is known to excreted in breastmilk. It is not recommended in breastfeeding women unless necessary. Avoid direct contact of this medicine with the baby.

Allergy

Not recommended in patients with known allergy to Ivermectin.
Warnings for special population

Pregnancy

This medicine is not recommended for pregnant women unless necessary. The risk and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is known to excreted in breastmilk. It is not recommended in breastfeeding women unless necessary. Avoid direct contact of this medicine with the baby.
General warnings

Mazzotti reaction

Patients being treated with Ivermectin for onchocerciasis may experience mazzotti reaction which are cutaneous and systemic adverse effect. These patients should be monitored closely. Supportive care should be initiated based on the severity.

Pretreatment assessment for Loa loa infection

Patients with significant exposure to endemic areas and being treated with Ivermectin for onchocerciasis may have an increase in the risk of fatal encephalopathy. The symptoms include neck pain, red eye, urinary and fecal incontinence, mental status changes, seizures, or coma. Therefore, pretreatment assessment for loiasis is necessary.

Pediatric use

This medicine is not recommended for children with body weight less than 15 kg.

Missed Dose

Take the missed dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose.

Overdose

Seek emergency medical treatment or contact the doctor in case of an overdose.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Consumption of alcohol may increase the effect of Ivermectin.

Instructions

Consumption of alcohol is not recommended in patients receiving Ivermectin. It may increase the concentration of this medicine and can cause skin rash, headache, dizziness, vomiting, diarrhea, and abdominal pain.
Interaction with Medicine

Oxcarbazepine

Warfarin

Disease interactions

Disease

Information not available.
Food interactions
Information not available.
Lab interactions
Information not available.
Take Ivermectin as advised by the doctor. Do not take in larger quantities than advised. The cream should be applied on the affected area without count with eyes, lips, and mucosa. Do not take if you have any allergy to this medicine. Inform the doctor if you develop any skin reactions.
Miscelleneous

To be taken on an empty stomach

To be taken as instructed by doctor

May cause sleepiness

How it works
It works by paralyzing the parasite and inhibits its growth.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Anthelmintics

Schedule

OTC

[Internet]. 2017 [cited 18 May 2017]. Available from:

https://www.medicines.org.uk/emc/medicine/30353

Ivermectin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 18 May 2017]. Available from:

https://medlineplus.gov/druginfo/meds/a607069.html

DailyMed - Ivermectin tablet [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 18 May 2017]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=847a1dd7-d65b-4a0e-a67d-d90392059dac

Prescribing medicines in pregnancy database [Internet]. Therapeutic Goods Administration (TGA). 2017 [cited 18 May 2017]. Available from:

https://www.tga.gov.au/prescribing-medicines-pregnancy-database#searchname

[Internet]. Toxnet.nlm.nih.gov. 2017 [cited 18 May 2017]. Available from:

https://toxnet.nlm.nih.gov/cgi-bin/sis/search2

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Information on this page was last updated on 16 Nov 2017

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.