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Itaspor 100 MG Injection
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Itaspor 100 MG Injection

Manufactured byIntas Pharmaceuticals Ltd.
ContainsItraconazole
Description
Itaspor 100 MG Injection is an azole antifungal that is used for empiric therapy of febrile neutropenic patients with suspected fungal infections. It is also used to treat certain types of fungal infections in immunocompromised and non-immunocompromised patients.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Itaspor 100 MG Injection

  • Convulsions
  • Dry mouth
  • Irregular heartbeat
  • Increased thirst
  • Abdominal pain
  • Decreased urine output
  • Diarrhea
  • Dizziness
  • Nervousness
  • Weight gain
  • Pain at the injection site
  • Trouble sleeping
  • Acid or sour stomach
  • Heartburn

Uses of Itaspor 100 MG Injection

What is it prescribed for?

  • Blastomycosis
  • Histoplasmosis
  • Invasive Aspergillosis
  • Cryptococcal Meningitis
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    The amount of time for which this medicine remains active in the body is not clinically established.
  • Is it safe to consume alcohol while taking this medicine?
    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
  • Is this a habit forming medicine?
    No habit forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Allergy

This medicine is not recommended for use in patients with a known allergy to itraconazole or any other inactive ingredients present in the formulation.

QT Interval prolonging drugs

This medicine is not recommended for co-administration with drugs like dofetilide, pimozide, quinidine, and cisapride that are known to cause elevated plasma concentrations of this medicine and may prolong the QT interval.

Severe renal impairment

This medicine is not recommended for use in patients with severe kidney impairment (creatine clearance <30 ml/min) due to the risk of adverse effects.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before receiving this medicine.
General warnings

Liver injury

This medicine should be used with caution in patients with liver diseases due to the increased risk of severe adverse effects. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

QT prolongation

This medicine should be used with extreme caution in patients with a known history of arrhythmias, heart diseases, and patients who are on medicines that prolong QT intervals due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative should be considered in some cases based on the clinical condition.

Hearing loss

This medicine may cause transient or permanent hearing loss when taken with quinidine. Close monitoring of any symptoms of any hearing problem is necessary. Discontinue the treatment if symptoms persist.

Cystic fibrosis

This medicine should be used with caution in patients with cystic fibrosis due to the increased risk of severe adverse effects. Close monitoring of the clinical condition, appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Neuropathy

This medicine may cause weakness, numbness, and pain in hands and feet. Appropriate corrective measures, dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

Driving or operating machinery

This medicine may cause dizziness or drowsiness in some patients. It is advised that you do not perform any activities that require high mental alertness like driving a vehicle or operating machinery if you experience any of these symptoms during or immediately after treatment with this medicine.

Missed Dose

Since this medicine is usually administered by a qualified healthcare professional in the clinical/hospital setting, the likelihood of a missed dose is very low.

Overdose

Since this medicine is administered in the hospital setting by a qualified healthcare professional, the likelihood of an overdose is very less. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.
Interaction with Medicine

Alprazolam

Erythromycin

Warfarin

Atorvastatin

Disease interactions

Liver Disease

This medicine should be used with caution in patients with liver diseases due to the increased risk of liver toxicity. Close monitoring of liver function tests is necessary while receiving this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

QT Prolongation

This medicine should be used with extreme caution in patients with a known history of arrhythmias, heart diseases, and patients who are on medicines that prolong QT intervals such as psychiatric drugs and anti-arrhythmic drugs. This medicine may further prolong QT intervals in such patients and worsen the patient's condition. Replacement with a suitable alternative should be considered in some cases based on the clinical condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
This medicine is usually administered in the clinical/hospital setting under the supervision of a qualified healthcare professional. Follow all the instructions given by your doctor. Inform the doctor if you have a known allergy to this medicine. Report all your current medicines as well as your medical conditions to the doctor before receiving this medicine.
Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine acts by stopping the production of a certain vital component for the fungi. This results in the disruption of the cell membrane formation process and inhibits the growth of the organism.
Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Azole antifungals

Schedule

Schedule H

Sporanox I.V. 10 mg/ml concentrate and solvent for solution for infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2020 [cited 20 January 2020]. Available from:

https://www.medicines.org.uk/emc/product/5522/smpc

[Internet]. Accessdata.fda.gov. 2020 [cited 20 January 2020]. Available from:

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020966s022lbl.pdf

Itraconazole - DrugBank [Internet]. Drugbank.ca. 2020 [cited 20 January 2020]. Available from:

https://www.drugbank.ca/drugs/DB01167
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Information on this page was last updated on 29 Jan 2020

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.