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Invega Sustenna 75 mg Injection

Manufactured byJANSSEN
ContainsPaliperidone
Description

Invega Sustenna 75 mg Injection is an antipsychotic agent used to treat symptoms of schizophrenia, including but not limited to disturbances in thinking, feelings, and behavior. This medicine is not recommended for use in elderly patients with dementia due to the increased risk of death.

Side effects

Major & minor side effects for Invega Sustenna 75 mg Injection

  • Drooling
  • Loss of balance control
  • Restlessness
  • Muscle stiffness and trembling
  • Irregular heartbeat
  • Uncontrolled body movements
  • Chest pain
  • Confusion
  • Dizziness
  • Fainting
  • Slurred speech
  • Tremors
  • Headache
  • Sleep disturbances

Uses of Invega Sustenna 75 mg Injection

What is it prescribed for?

  • Schizophrenia
  • Schizoaffective disorder
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The amount of time required for this medicine to show its action is not clinically established.
  • How long do the effects of this medicine last?
    Oral use: The effect of this medicine lasts for an average duration of 24 hours. Intramuscular Use: The effect of this medicine lasts for an average duration of 1 month.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of dizziness, drowsiness, difficulty concentrating, etc.
  • Is this a habit forming medicine?
    No habit-forming tendencies were reported.
  • Can this medicine be taken during pregnancy?
    This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
  • Can this medicine be taken while breast-feeding?
    This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.

Allergy

This medicine is not recommended for use in patients with a known allergy to paliperidone, or any other inactive ingredients present in the formulation.

Cardiac arrythmia

This medicine is not recommended for use in patients suffering from cardiac arrhythmias due to the increased risk of worsening of the patient's condition.
Warnings for special population

Pregnancy

This medicine is not recommended for use in pregnant women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.

Breast-feeding

This medicine is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may prescribe a safer alternative based on your clinical condition.
General warnings

Tardive Dyskinesia

This medicine may cause involuntary movements of the tongue, lips, and face in some patients. Inform the doctor immediately if you have any of these symptoms. Appropriate dose adjustments or replacement with a suitable alternative may be necessary based on the clinical condition.

Seizures

This medicine should be used with caution in patients with a history of seizure disorder due to the increased risk of recurrent seizures. Report any unusual symptoms to the doctor immediately. Appropriate patient/caregiver education, dose adjustments, or replacement with a suitable alternative may be required based on the clinical condition.

Alteration in blood glucose and lipid levels

This medicine should be used with caution since it may alter the blood glucose and lipid levels. Blood glucose and lipid levels should be obtained before beginning therapy with this medicine and should be closely monitored during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in some cases based on the clinical condition.

Use in pediatrics

This oral form of this medicine is not recommended for use in patients below 12 years of age and the intramuscular form of this medicine is not recommended for use in patients below 18 years of age.

Driving or Operating machinery

This medicine may cause symptoms such as dizziness, blurred vision, muscle stiffness, loss of balance, etc. in some patients. Hence, it is advised that you do not perform any activities such as driving a vehicle or operating machinery during treatment with this medicine.

Missed Dose

Oral form: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed dose. Injection: Since this medicine is administered by a qualified healthcare professional, the likelihood of a missed dose is very low. If you miss an appointment for a scheduled dose of this medicine, contact your doctor immediately for further instructions.

Overdose

Oral form: Seek emergency medical treatment or contact the doctor in case of an overdose. Injection: Since this medicine is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with this medicine due to the increased risk of dizziness, drowsiness, difficulty concentrating, etc.
Interaction with Medicine

Escitalopram

Antihypertensives

Diazepam

Bupropion

Citalopram

Haloperidol

Lamotrigine

Duloxetine

Lithium

Disease interactions

Dementia

This medicine is not recommended for use in patients with dementia-related psychosis due to the increased risk of heart failure, pneumonia, death, etc. This risk is especially high in elderly patients. Replacement with a suitable alternative should be considered under your doctor's supervision.

Tardive Dyskinesia

This medicine should be used with extreme caution in patients suffering from tardive dyskinesia since it may worsen the patient's condition. Report any unusual symptoms to the doctor on priority. Appropriate patient/caregiver education, close monitoring of patient's condition, dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition.

Hypotension

This medicine should be used with caution in patients with a known history of hypotension (low blood pressure) due to the increased risk of worsening of the patient's condition. Close monitoring of blood pressure levels, appropriate dose adjustments, or replacement with a suitable alternative may be necessary based on the clinical condition. Patients are advised to get up slowly from a sitting or a lying position to avoid fainting and falling.
Food interactions
Information not available.
Lab interactions
Information not available.
Oral: Take this medicine with or without food. Do not take in larger or smaller amounts than advised/prescribed. Consult the doctor if you experience any undesirable side effects. Ensure that the treatment course is completed. Do not stop the use of this medicine without consulting your doctor. Injection: This medicine is usually administered by a qualified healthcare professional. Inform the doctor if you have a known allergy to this medicine. Report to the doctor all your current medicines as well as your medical conditions before receiving this medicine.
Miscelleneous

Can be taken with or without food, as advised by your doctor

To be taken as instructed by doctor

May cause sleepiness

How it works
This medicine inhibits the release of certain specific chemical substances that are responsible for causing psychotic symptoms.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Atypical antipsychotics

Schedule

Schedule H

Paliperidone - DrugBank [Internet]. Drugbank.ca. 2018 [cited 22 March 2018]. Available from:

https://www.drugbank.ca/drugs/DB01267

DailyMed - paliperidone tablet, extended release [Internet]. Dailymed.nlm.nih.gov. 2018 [cited 22 March 2018]. Available from:

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=9089db76-aa50-417d-bf62-3674df161e9a

[Internet]. Davisplus.fadavis.com. 2018 [cited 22 March 2018]. Available from:

https://davisplus.fadavis.com/3976/meddeck/pdf/paliperidone.pdf

[Internet]. Ec.europa.eu. 2018 [cited 22 March 2018]. Available from:

https://ec.europa.eu/health/documents/community-register/2015/20151216133533/anx_133533_en.pdf

[Internet]. Medicines.org.uk. 2018 [cited 22 March 2018]. Available from:

https://www.medicines.org.uk/emc/files/pil.7652.pdf

[Internet]. Medicines.org.uk. 2018 [cited 22 March 2018]. Available from:

https://www.medicines.org.uk/emc/files/pil.6818.pdf

[Internet]. Janssen.com. 2018 [cited 22 March 2018]. Available from:

http://www.janssen.com/newzealand/sites/www_janssen_com_newzealand/files/prod_files/live/invega.pdf
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Information on this page was last updated on 20 Jun 2020

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