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Insugen-50/50 Refil Injection
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Insugen-50/50 Refil Injection

Manufactured byBIOCON LTD
ContainsRegular Human Insulin (50 International units ) + Insulin - Neutral Protaminated Hagedorn (NPH) (50 International units )
Description
Insugen-50/50 Refil Injection is an anti-diabetic medicine containing regular human Insulin and Isophane Insulin. Insulin is a natural substance produced by the pancreas which helps in utilizing glucose for energy production. It is used in the treatment of Diabetes mellitus (a group of conditions resulting in increased blood sugar levels in the body) in children and adults. This medicine provides consistent sugar control by improving the utilization of glucose by muscles and fat cells and by decreasing the protection of sugar in the liver. Insugen-50/50 Refil Injection can have side effects like itching, skin rash, weight gain, swelling and pain at the site of injection. This medicine can occasionally cause hypoglycaemia (low blood sugar levels), the signs of which are sweating, dizziness, and shaking. To avoid the symptoms of low blood sugar levels, eat your meals on time and carry a fast-acting sugar source (sweet candy or fruit juice). Insugen-50/50 Refil Injection is a prescription medicine. Your doctor or the supporting nurse will explain how to administer this injection and the precautions to be taken while administering it. This medicine should be taken 30 minutes before a meal. Do not stop taking this injection without consulting your doctor, even if your sugar levels are normal. Insugen-50/50 Refil Injection is mostly given in combination with oral anti-diabetic medicine. Inform your doctor if you have liver, kidney, heart problems and also about your ongoing medicines, before taking this medicine. Also, before taking this injection, inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding.
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Side effectsConcernsUsageRelated products

Side effects

Major & minor side effects for Insugen-50/50 Refil Injection

  • Decreased blood glucose levels
  • Abdominal and stomach pain
  • Tingling of hands or feet
  • Dry mouth
  • Diarrhoea
  • Sore throat
  • Headache
  • Sneezing
  • Fever
  • Body pain
  • Unusual weight gain or loss
  • Nausea and Vomiting
  • Pain at the injection site
  • Dizziness
  • Drowsiness
  • Confusion

Uses of Insugen-50/50 Refil Injection

What is it prescribed for?

  • Type I Diabetes mellitus
  • Type II Diabetes Mellitus
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Concerns

Commonly asked questions

  • How long does it take for this medicine to take effect?
    The effect of Insugen-50/50 Refil Injection can be observed within 30 minutes of administration.
  • How long do the effects of this medicine last?
    The effect of Insugen-50/50 Refil Injection lasts for an average duration of 14 to 24 hours.
  • Is it safe to consume alcohol while taking this medicine?
    Consumption of alcohol is not recommended during treatment with Insugen-50/50 Refil Injection as it may increase the risk of lactic acidosis (increased blood lactic acid levels). It may also affect the ability of this medicine to control your blood sugar levels.
  • Is this a habit forming medicine?
    No habit-forming tendency has been reported for Insugen-50/50 Refil Injection.
  • Can this medicine be taken during pregnancy?
    Insugen-50/50 Refil Injection is generally safe during pregnancy. However, if you are pregnant, consult your doctor before using this medicine.
  • Can this medicine be taken while breast-feeding?
    Insugen-50/50 Refil Injection is considered safe during breastfeeding. However, if you are breastfeeding, consult your doctor before using this medicine.

Allergy

Avoid using Insugen-50/50 Refil Injection if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Hypoglycemia

Hypoglycemia is a condition of decreased blood sugar levels in the body. Insugen-50/50 Refil Injection is not recommended for use if you have decreased blood sugar levels, as this may worsen your health condition leading to serious side effects.
Warnings for special population

Pregnancy

Insugen-50/50 Refil Injection is generally safe during pregnancy. However, if you are pregnant, consult your doctor before using this medicine.

Breast-feeding

Insugen-50/50 Refil Injection is considered safe during breastfeeding. However, if you are breastfeeding, consult your doctor before using this medicine.
General warnings

Liver/Kidney diseases

Insugen-50/50 Refil Injection should be used with caution if you have any history of liver/kidney problems as it may lead to worsening of your health condition. Your doctor may suggest tests to monitor your kidney/liver functioning while on treatment with this medicine.

Hypokalaemia

Insugen-50/50 Refil Injection should be used with caution if you have an increased risk of developing hypokalemia (decreased blood potassium levels) as it may worsen your health condition.

Driving and Operating machines

Insugen-50/50 Refil Injection may cause low blood sugar levels and dizziness which may affect your concentration. Avoid driving vehicles or operating machines if you experience these symptoms after taking this medicine.

Changing the type and brand of insulin

Do not use other brands or types of insulin without consulting your doctor, once you started using Insugen-50/50 Refil Injection.

Single Person Use

Insugen-50/50 Refil Injection (pen) should not be shared with others even if the needle is changed. Sharing insulin pens, syringes and needles with another person, who are using vials is strictly not advised.

Subcutaneous use only

Insugen-50/50 Refil Injection is meant for subcutaneous administration only. The long duration of action of this medicine is based on its subcutaneous administration. It should not be administered intravenously or intramuscularly.

Missed Dose

Administer the missed dose of Insugen-50/50 Refil Injection as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not double your dose to make up for the missed one.

Overdose

Seek immediate medical attention if an overdose of Insugen-50/50 Refil Injection is suspected.
All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.
Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended during treatment with Insugen-50/50 Refil Injection as it may increase the risk of lactic acidosis (increased blood lactic acid levels). It may also affect the ability of this medicine to control your blood sugar levels.
Interaction with Medicine

Corticosteroids

Beta blockers

ACE inhibitors

Gatifloxacin

Fluoroquinolones

Disease interactions

Hypoglycemia

Hypoglycemia is a condition characterized by a decrease in your blood glucose levels. Insugen-50/50 Refil Injection is not recommended for use if you have low blood sugar levels. Monitor your blood glucose level regularly. Always carry a fast-acting sugar source (like sugar candy or fruit juice) to overcome the symptoms of hypoglycemia.

Heart diseases

Insugen-50/50 Refil Injection should be used with caution if you have pre-existing heart problems due to the increased risk of worsening your condition.
Food interactions
Information not available.
Lab interactions
Information not available.
This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.
Carefully follow all the instructions given by your doctor while administering Insugen-50/50 Refil Injection. Never administer more or less than the prescribed dose. Do not stop the use of this medicine without consulting your doctor. Consult your doctor if you experience any undesirable side effects while using this medicine. Frequent follow-up visits with your doctor and monthly blood tests may be required based on your health condition. Never share an injection pen, cartridge, or syringe with another person, even if the needle has been changed. Maintain a proper diet and do regular exercise to get maximum benefits. You should always carry a sugar candy to counteract unexpected lowering of blood sugar levels. Store in a refrigerator. Do not freeze. Keep away from the reach of children and pets.
Miscelleneous

To be taken before food

To be taken as instructed by doctor

May cause sleepiness

How it works
Insugen-50/50 Refil Injection is a replacement insulin that works by enhancing the glucose uptake for energy production. This helps in controlling blood sugar levels. Regular insulin is a short-acting insulin that starts its action within 30 minutes of administration. Insulin - Neutral Protaminated Hagedorn is an intermediate-acting insulin that has a prolonged duration of action. This combination provides consistent sugar control by improving the utilization of glucose by muscles and fat cells and by decreasing the protection of sugar in the liver.
Legal Status

Approved

Approved

Approved

Approved

Classification

Category

Insulin, Insulin analog combination

Schedule

Schedule H

Biocon.com. 2021. [online] Available at: < [Accessed 29 November 2021].

https://www.biocon.com/products/branded-formulations/metabolics-branded-formulations-2/#1596651982962-1ae6f05b-1fcd>

Ebs.tga.gov.au. 2021. TGA eBS - Product and Consumer Medicine Information Licence. [online] Available at: < [Accessed 29 November 2021].

https://www.ebs.tga.gov.au/ebs/picmi/picmirepository.nsf/pdf?OpenAgent&id=CP-2011-PI-02733-3&d=201905171016933>

Nps.org.au. 2021. [online] Available at: < [Accessed 29 November 2021].

https://www.nps.org.au/assets/medicines/5fa2a30c-48cf-4e3d-a801-a53300ff95ad.pdf>
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Information on this page was last updated on 3 Dec 2021

Disclaimer

We’ve made all possible efforts to ensure that the information provided here is accurate, up-to-date and complete, however, it should not be treated as a substitute for professional medical advice, diagnosis or treatment. Practo only provides reference source for common information on medicines and does not guarantee its accuracy or exhaustiveness. The absence of a warning for any drug or combination thereof, should not be assumed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Practo does not assume any responsibility for any aspect of healthcare administered with the aid of information provided above. If you have any doubts about your medication then we strongly recommend that you consult with your doctor, nurse or healthcare provider. See detailed T&C here.